Real-Time Quantitative Reverse Transcription-PCR for Cyclin D1 mRNA in Blood, Marrow, and Tissue Specimens for Diagnosis of Mantle Cell Lymphoma
Howe JG, Crouch J, Cooper D, Smith BR. Real-Time Quantitative Reverse Transcription-PCR for Cyclin D1 mRNA in Blood, Marrow, and Tissue Specimens for Diagnosis of Mantle Cell Lymphoma. Clinical Chemistry 2004, 50: 80-87. PMID: 14633913, DOI: 10.1373/clinchem.2003.024695.Peer-Reviewed Original ResearchConceptsMantle cell lymphomaReal-time reverse transcription PCRCases of MCLCyclin D1 mRNAQuantitative RT-PCRLymphoproliferative diseaseReverse transcription-PCRCell lymphomaD1 mRNAMicroglobulin mRNADiagnosis of MCLTranscription-PCRCyclin D1 mRNA expressionB cell-specific markersCritical diagnostic markerReal-time quantitative RT-PCRD1 mRNA expressionTime quantitative reverse transcription PCRQuantitative reverse transcription PCROvert diseaseMarrow specimensAmbiguous immunophenotypeCD19 mRNAMalignant cellsTissue specimens