Phase I/II Study of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor in Aplastic Anemia and Myelodysplastic Syndrome
Antin J, Smith B, Holmes W, Rosenthal D. Phase I/II Study of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor in Aplastic Anemia and Myelodysplastic Syndrome. Blood 1988, 72: 705-713. DOI: 10.1182/blood.v72.2.705.705.Peer-Reviewed Original ResearchPhase I/II studyAplastic anemiaMyelodysplastic syndromeII studyReticulocyte countErythrocyte transfusion requirementsLow-grade feverMyalgia/arthralgiaMicrograms/m2Four-hour intravenous infusionRecombinant human granulocyte-macrophage colony-stimulating factorNumber of eosinophilsGM-CSF therapyImmature myeloid cellsGranulocyte-macrophage colony-stimulating factorRecombinant human granulocyte-macrophage colonyLow back discomfortColony-stimulating factorHuman granulocyte-macrophage colony-stimulating factorGranulocyte-macrophage colonyTransfusion requirementsIntravenous infusionPlatelet countBlood countGranulocyte count