2018
False-Positive Light Chain Clonal Restriction by Flow Cytometry in Patients Treated With Alemtuzumab
Chen PP, Tormey CA, Eisenbarth SC, Torres R, Richardson SS, Rinder HM, Smith BR, Siddon AJ. False-Positive Light Chain Clonal Restriction by Flow Cytometry in Patients Treated With Alemtuzumab. American Journal Of Clinical Pathology 2018, 151: 154-163. PMID: 30307483, DOI: 10.1093/ajcp/aqy129.Peer-Reviewed Original ResearchConceptsHealthy donor bloodAlemtuzumab treatmentDonor bloodBone marrowFlow cytometryLight chain restrictionT-cell prolymphocytic leukemiaB-cell neoplasmsLight chain clonalityFlow cytometry analysisAutoimmune diseasesHematologic malignanciesImmunophenotypic analysisChain restrictionAlemtuzumabT cellsB cellsProlymphocytic leukemiaImmunoglobulin G1PatientsMonoclonal antibodiesCytometry analysisSimilar findingsBloodClonal restriction
2008
DNA ploidy analysis as an adjunct for the detection of relapse in B-lineage acute lymphoblastic leukemia
Kenney B, Zieske A, Rinder H, Smith B. DNA ploidy analysis as an adjunct for the detection of relapse in B-lineage acute lymphoblastic leukemia. Leukemia & Lymphoma 2008, 49: 42-48. PMID: 18203010, DOI: 10.1080/10428190701760052.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaDetection of relapseDNA ploidy analysisLymphoblastic leukemiaPloidy analysisB-lineageB-lineage acute lymphoblastic leukemiaCytometric DNA ploidy analysisDiagnosis of relapseNormal precursor B cellsPrecursor B cellsOriginal immunophenotypeRelapsed diseaseUnique immunophenotypeLeukemic immunophenotypesImmunophenotypic detectionRelapseB cellsPatientsImmunophenotypeFlow immunophenotypingFlow cytometryAneuploid populationsDiagnosisLeukemia
2003
Systemic Tropheryma whippleii infection associated with monoclonal B-cell proliferation: a Helicobacter pylori-type pathogenesis?
Wang S, Ernst LM, Smith BR, Tallini G, Howe JG, Crouch J, Cooper DL. Systemic Tropheryma whippleii infection associated with monoclonal B-cell proliferation: a Helicobacter pylori-type pathogenesis? Archives Of Pathology & Laboratory Medicine 2003, 127: 1619-22. PMID: 14632565, DOI: 10.5858/2003-127-1619-stwiaw.Peer-Reviewed Original ResearchConceptsMonoclonal B-cell proliferationLymph nodesB cell proliferationWhipple's diseasePeripheral bloodPolymerase chain reactionB cellsRight axillary lymph nodeAxillary lymph nodesMesenteric lymph nodesMonoclonal B-cell populationTime of presentationPatients' peripheral bloodPrevious biopsy specimensChain reactionB-cell lymphomaMonoclonal B cellsB cell populationsPeriodic acid-Schiff stainFlow cytometry studiesRoutine cytogenetic studiesEntire followMesenteric lymphBiopsy specimensImmunohistochemical stains
1994
B-Cell Precursor Bone Marrow Reconstitution After Bone Marrow Transplantation
Leitenberg D, Rappeport J, Smith B. B-Cell Precursor Bone Marrow Reconstitution After Bone Marrow Transplantation. American Journal Of Clinical Pathology 1994, 102: 231-236. PMID: 8042594, DOI: 10.1093/ajcp/102.2.231.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntigens, CDBlotting, SouthernB-LymphocytesBone MarrowBone Marrow CellsBone Marrow TransplantationChildChild, PreschoolClone CellsFemaleFlow CytometryFluorescent Antibody TechniqueGene Rearrangement, B-Lymphocyte, Heavy ChainHematopoietic Stem CellsHumansImmunophenotypingInfantKineticsMaleMiddle AgedNeprilysinConceptsBone marrow transplantationMarrow transplantationB cell subsetsBone marrow reconstitutionB cell precursorsSurface antigenic phenotypeImmature B cellsImmunoglobulin gene rearrangementsHumoral immunodeficiencyMonoclonal gammapathyMarrow reconstitutionAntigenic phenotypeB cellsTransplantationGene rearrangementsMarked increaseLeukemia lymphoblastsCellsPatientsGammapathyImmunodeficiencyMarrowCD34ReconstitutionMonths
1989
A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation.
Bierer B, Burakoff S, Smith B. A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation. Blood 1989, 73: 1359-66. PMID: 2467708, DOI: 10.1182/blood.v73.5.1359.bloodjournal7351359.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAntigens, DifferentiationAntigens, Differentiation, T-LymphocyteBone Marrow TransplantationCalciumCD3 ComplexCD5 AntigensCytoplasmCytotoxicity, ImmunologicGraft vs Host DiseaseHumansImmunologic Deficiency SyndromesInterleukin-2Leukocyte CountMicePhenotypeReceptors, Antigen, T-CellT-Lymphocytes, CytotoxicConceptsBone marrow transplantationCD5 expressionMarrow transplantationT cellsAllogeneic bone marrow transplantationFrequency of CD3Major histocompatibility complex compatibilityT-cell depletionPercent of CD8Expression of CD5Presence of graftBMT patientsTotal CD3Host diseaseInterstitial pneumonitisPreparative regimenPeripheral bloodT lymphocytesB cellsCD3Lectin stimulationPatientsNormal populationTransplantationCD5A Large Proportion of T Lymphocytes Lack CD5 Expression After Bone Marrow Transplantation
Bierer B, Burakoff S, Smith B. A Large Proportion of T Lymphocytes Lack CD5 Expression After Bone Marrow Transplantation. Blood 1989, 73: 1359-1366. DOI: 10.1182/blood.v73.5.1359.1359.Peer-Reviewed Original ResearchBone marrow transplantationCD5 expressionMarrow transplantationT cellsAllogeneic bone marrow transplantationFrequency of CD3Major histocompatibility complex compatibilityT-cell depletionPercent of CD8Expression of CD5Presence of graftBMT patientsTotal CD3Host diseaseInterstitial pneumonitisPreparative regimenPeripheral bloodT lymphocytesB cellsCD3Lectin stimulationPatientsNormal populationTransplantationCD5
1987
B lymphocyte reconstitution after human bone marrow transplantation. Leu-1 antigen defines a distinct population of B lymphocytes.
Antin JH, Ault KA, Rappeport JM, Smith BR. B lymphocyte reconstitution after human bone marrow transplantation. Leu-1 antigen defines a distinct population of B lymphocytes. Journal Of Clinical Investigation 1987, 80: 325-332. PMID: 3112184, PMCID: PMC442241, DOI: 10.1172/jci113076.Peer-Reviewed Original ResearchConceptsLeu-1B cellsMarrow transplantationHuman bone marrow transplantationEffect of GVHDHuman marrow transplantationBone marrow transplantationEx vivo treatmentInterleukin-2 receptorB lymphocyte reconstitutionSeparate B cell lineageNormal B cellsB-cell lineageAcute GVHDChronic graftHost diseaseLymphocyte reconstitutionDonor originVivo treatmentB lymphocytesMultivariate analysisStages of differentiationGVHDTransplantationMarrow
1985
Phenotype of recovering lymphoid cell populations after marrow transplantation.
Ault KA, Antin JH, Ginsburg D, Orkin SH, Rappeport JM, Keohan ML, Martin P, Smith BR. Phenotype of recovering lymphoid cell populations after marrow transplantation. Journal Of Experimental Medicine 1985, 161: 1483-1502. PMID: 3159819, PMCID: PMC2187630, DOI: 10.1084/jem.161.6.1483.Peer-Reviewed Original Research