1998
Differences in Platelet α-granule Release between Normals and Immune Thrombocytopenic Patients and between Young and Old Platelets
Rinder HM, Tracey JB, Recht M, DeCastro L, Rinder CS, McHugh C, Smith BR. Differences in Platelet α-granule Release between Normals and Immune Thrombocytopenic Patients and between Young and Old Platelets. Thrombosis And Haemostasis 1998, 80: 457-462. PMID: 9759627, DOI: 10.1055/s-0037-1615229.Peer-Reviewed Original ResearchConceptsImmune thrombocytopenic purpuraThrombin receptor agonist peptideAlpha-granule releaseITP patientsOld plateletsThrombocytopenic patientsImmune thrombocytopenic patientsPlatelet α-granule releaseΑ-granule releaseNormal human controlsMaintenance of hemostasisControl RPSerious bleedingThrombocytopenic purpuraMegakaryocytic hypoplasiaPatient groupReticulated plateletsNormal controlsPatientsPlatelet responseAgonist peptideYoung plateletsPlateletsHemostatic activityCD62P
1993
Aspirin Does Not Inhibit Adenosine Diphosphate-Induced Platelet α-Granule Release
Rinder C, Student L, Bonan J, Rinder H, Smith B. Aspirin Does Not Inhibit Adenosine Diphosphate-Induced Platelet α-Granule Release. Blood 1993, 82: 505-512. PMID: 7687162, DOI: 10.1182/blood.v82.2.505.505.Peer-Reviewed Original ResearchConceptsP-selectin expressionAlpha-granule secretionPlatelet alpha-granule secretionAspirin treatmentP-selectinGranule secretionPlatelet alpha-granule releaseArachidonic acidCyclooxygenase-dependent metabolitesPlatelet surface expressionPlatelet α-granule releasePlatelet dense granule secretionAlpha-granule releaseΑ-granule releaseDense granule secretionPolymorphonuclear lymphocytesAmiloride treatmentLipoxygenase inhibitorsAspirinSecretionWhole bloodPlatelet-platelet interactionsTreatmentInvolvement of metabolitesPlatelets