Structural Insights into RNA Recognition by RIG-I
Luo D, Ding SC, Vela A, Kohlway A, Lindenbach BD, Pyle AM. Structural Insights into RNA Recognition by RIG-I. Cell 2011, 147: 409-422. PMID: 22000018, PMCID: PMC3222294, DOI: 10.1016/j.cell.2011.09.023.Peer-Reviewed Original ResearchConceptsPathogen-associated molecular patternsTerminal regulatory domainProtein familyRegulatory domainProtein domainsInsertion domainRNA recognitionMolecular basisATP hydrolysisStructural insightsIntracellular RIGRNAMolecular patternsMotor domainLike receptorsAntiviral immune responseViral RNANanomechanical FunctionDomainHelicasesComplex interplayHelicaseCladeHel2DsRNA