2023
Video-telecare collaborative pain management during COVID-19: a single-arm feasibility study
Rogers D, Frank J, Wesolowicz D, Nolan C, Schroeder A, Falker C, Abelleira A, Moore B, Becker W, Edmond S. Video-telecare collaborative pain management during COVID-19: a single-arm feasibility study. BMC Primary Care 2023, 24: 134. PMID: 37386370, PMCID: PMC10308713, DOI: 10.1186/s12875-023-02052-2.Peer-Reviewed Original ResearchConceptsMorphine equivalent daily doseSingle-arm feasibility studyEquivalent daily dosePain managementDaily doseLong-term opioid therapyInitial intakeMultiple appointmentsNon-pharmacologic interventionsOpioid use disorderPrimary care providersPain management programGuideline-based careEvidence-based interventionsBackgroundChronic painOpioid therapyBehavioral painChronic painPrimary careCommon conditionCare providersPatientsU.S. veteransPainPreliminary data
2022
Opioid tapering support using a web-based app: Development and protocol for a pilot randomized controlled trial
Edmond SN, Wesolowicz DM, Moore BA, Ibarra J, Chhabra M, Fraenkel L, Becker WC. Opioid tapering support using a web-based app: Development and protocol for a pilot randomized controlled trial. Contemporary Clinical Trials 2022, 119: 106857. PMID: 35863697, DOI: 10.1016/j.cct.2022.106857.Peer-Reviewed Original ResearchConceptsPilot trialLong-term opioid therapyPatient-reported outcomesRandomized-controlled trialQuality of lifeSelf-management skillsOpioid taperOpioid therapyOpioid usePrimary outcomePrimary careTwo-armLimited efficacyInteractive web-based programControl groupIntervention MappingWeb-based programPatientsPeer specialistsTrialsPotential harmSummit programWeb-based appCareOutcomesSubstance Use–Related Continuing Education Course Objectives: Alignment with Professional Competencies
Finnell DS, Soltis-Jarrett V, Bratberg J, Muzyk A, Liu Y, Edens E, Seale JP, Mattingly J, Schnurman K, Osborne-Leute V, Zweben A, Cary A, Moore BA. Substance Use–Related Continuing Education Course Objectives: Alignment with Professional Competencies. Substance Use & Addiction Journal 2022, 43: 1363-1369. PMID: 36094441, DOI: 10.1080/08897077.2022.2112365.Peer-Reviewed Original Research
2021
Twelve-Month Retention in Opioid Agonist Treatment for Opioid Use Disorder Among Patients With and Without HIV
Wyse JJ, McGinnis KA, Edelman EJ, Gordon AJ, Manhapra A, Fiellin DA, Moore BA, Korthuis PT, Kennedy AJ, Oldfield BJ, Gaither JR, Gordon KS, Skanderson M, Barry DT, Bryant K, Crystal S, Justice AC, Kraemer KL. Twelve-Month Retention in Opioid Agonist Treatment for Opioid Use Disorder Among Patients With and Without HIV. AIDS And Behavior 2021, 26: 975-985. PMID: 34495424, PMCID: PMC8840957, DOI: 10.1007/s10461-021-03452-0.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyOpioid use disorderVeterans Aging Cohort StudyHIV statusUse disordersOpioid agonist treatmentAging Cohort StudyDiagnosis of HCVTwelve-month retentionPositive health outcomesOAT retentionAgonist therapyCohort studyHIV managementAgonist treatmentPredictors of retentionPatientsHealth outcomesHistory of homelessnessHIVLower likelihoodImproved likelihoodLikelihood of initiationBuprenorphineDisordersMicrobial burden on environmental surfaces in patient rooms before daily cleaning—Analysis of multiple confounding variables
Boyce JM, Havill NL, Guercia KA, Moore BA. Microbial burden on environmental surfaces in patient rooms before daily cleaning—Analysis of multiple confounding variables. Infection Control And Hospital Epidemiology 2021, 43: 1142-1146. PMID: 34396941, DOI: 10.1017/ice.2021.349.Peer-Reviewed Original ResearchConceptsMicrobial burdenPatient roomsStudy periodIntensive care unitType of wardMultivariable regression analysisMultiple confounding variablesMedical wardsCare unitCrossover trialHospital environmental surfacesWard typeBedside railsEnvironmental surfacesCompliance rateConfounding variablesHigh-touch surfacesWardsLarge hospitalsAdditional studiesConvenience sampleRegression analysisDaily cleaningBurdenQuaternary ammonium disinfectantA multi-center outbreak of Candida tropicalis bloodstream infections associated with contaminated hemodialysis machine prime buckets
Boyce JM, Dumigan DG, Havill NL, Hollis RJ, Pfaller MA, Moore BA. A multi-center outbreak of Candida tropicalis bloodstream infections associated with contaminated hemodialysis machine prime buckets. American Journal Of Infection Control 2021, 49: 1008-1013. PMID: 33631306, DOI: 10.1016/j.ajic.2021.02.014.Peer-Reviewed Original ResearchConceptsBloodstream infectionsIndistinguishable pulsed-field gel electrophoresis (PFGE) patternsC tropicalisCase-control studyWarrants further evaluationPulsed-field gel electrophoresis patternsFungal bloodstream infectionsHands of personnelReview of recordsHemodialysis patientsHemodialysis unitPatientsPotential infection riskInfection riskFurther evaluationDialysis equipmentGel electrophoresis patternsInfectionRoutine disinfectionInadequate disinfectionCurrent useHigher proportionOutbreakHollow handleElectrophoresis patterns
2020
Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study.
Edelman EJ, Li Y, Barry D, Brennan Braden J, Crystal S, Kerns RD, Gaither JR, Gordon KS, Manhapra A, Merlin JS, Moore BA, Oldfield BJ, Park LS, Rentsch CT, Skanderson M, Williams EC, Justice AC, Tate JP, Becker WC, Marshall BDL. Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 84: 26-36. PMID: 32267658, PMCID: PMC7147724, DOI: 10.1097/qai.0000000000002310.Peer-Reviewed Original ResearchConceptsOpioid useOpioid use trajectoriesCohort studyPain interferenceSelf-reported opioid useVeterans Aging Cohort StudyVeterans Health Administration sitesInfrequent useOpioid use frequencyMarijuana useAging Cohort StudyNational cohort studyEvidence-based treatmentsGroup-based trajectory modelsProspective cohortBaseline factorsIllness severityMultivariable analysisBenzodiazepine medicationVA carePsychoactive medicationsPrescription painkillersPsychiatric symptomsHeroin useMultinomial logistic regression
2019
High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans.
Banerjee G, Edelman EJ, Barry DT, Crystal S, Gordon KS, Gordon AJ, Gaither JR, Green TC, Kerns RD, Manhapra A, Moore BA, Fiellin DA, Marshall BDL. High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans. Pain 2019, 160: 2126-2135. PMID: 31145217, PMCID: PMC6699915, DOI: 10.1097/j.pain.0000000000001606.Peer-Reviewed Original ResearchConceptsHigh-dose opioid prescriptionsOpioid prescriptionsHeroin useCohort studyPrior receiptHepatitis C virus (HCV) infection statusLong-term opioid prescriptionsPast-year heroin useVeterans Aging Cohort StudyHigh-dose opioidsOpioid-prescribing patternsProspective cohort studyAging Cohort StudyOpioid use disorderCurrent national guidelinesUnhealthy alcohol useUnited States veteransUnited States military veteransVirus infection statusPosttraumatic stress disorderOpioid receiptPrescribed opioidsPain interferenceCox regressionStates veteransPredictors of timely opioid agonist treatment initiation among veterans with and without HIV
Wyse JJ, Robbins JL, McGinnis KA, Edelman EJ, Gordon AJ, Manhapra A, Fiellin DA, Moore BA, Korthuis PT, Gaither JR, Gordon K, Skanderson M, Barry DT, Crystal S, Justice A, Kraemer KL. Predictors of timely opioid agonist treatment initiation among veterans with and without HIV. Drug And Alcohol Dependence 2019, 198: 70-75. PMID: 30878769, PMCID: PMC6836871, DOI: 10.1016/j.drugalcdep.2019.01.038.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyOpioid use disorderVeterans Aging Cohort StudyOAT initiationUninfected patientsClinical encountersNational observational cohortAging Cohort StudyAfrican American patientsImproved health outcomesAgonist therapyCohort studyObservational cohortTreatment initiationPredictive factorsEffective treatmentAdjusted modelUninfected controlsUse disordersPsychiatric diagnosisPWHClinical practicePatientsHealth outcomesRural residence
2018
A randomized clinical trial of the Recovery Line among methadone treatment patients with ongoing illicit drug use
Moore BA, Buono FD, Lloyd DP, Printz DMB, Fiellin DA, Barry DT. A randomized clinical trial of the Recovery Line among methadone treatment patients with ongoing illicit drug use. Journal Of Substance Use And Addiction Treatment 2018, 97: 68-74. PMID: 30577901, PMCID: PMC6310054, DOI: 10.1016/j.jsat.2018.11.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive Behavioral TherapyCombined Modality TherapyFemaleHumansIllicit DrugsMaleMethadoneMiddle AgedNarcoticsOpiate Substitution TreatmentOutcome and Process Assessment, Health CareSelf ReportSelf-Help GroupsSelf-ManagementSubstance Abuse DetectionSubstance-Related DisordersTelephoneConceptsMethadone treatment patientsIllicit drug useDrug useTreatment patientsUrine screensOngoing illicit drug useDrug abstinencePrevious small trialsClinical efficacy trialsSelf-reported abstinenceRandomized clinical trialsIllicit drugsSubstance use disordersSelf-management systemCognitive behavioral therapyAdjunctive treatmentPrimary outcomeMethadone treatmentSmall trialsClinical trialsEfficacy trialsAbstinence outcomesUse disordersPatient engagementPatientsProject STEP: Implementing the Veterans Health Administration’s Stepped Care Model of Pain Management
Edmond SN, Moore BA, Dorflinger LM, Goulet JL, Becker WC, Heapy AA, Sellinger JJ, Lee AW, Levin FL, Ruser CB, Kerns RD. Project STEP: Implementing the Veterans Health Administration’s Stepped Care Model of Pain Management. Pain Medicine 2018, 19: s30-s37. PMID: 30203015, DOI: 10.1093/pm/pny094.Peer-Reviewed Original ResearchConceptsVA Connecticut Healthcare SystemPrimary care providersVeterans Health AdministrationPain careStepped care modelCare providersPain managementCare modelHealth care utilization dataMultimodal pain careNonopioid analgesic prescribingLong-term opioidsElectronic health record dataPain intensity ratingsHealth record dataClinical health psychologyNonpharmacological servicesAnalgesic prescribingOpioid prescribingPharmacological managementNonpharmacological approachesNonpharmacological treatmentsReferral practicesPhysical therapyCare practicesEfficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial
Edelman EJ, Moore BA, Holt SR, Hansen N, Kyriakides TC, Virata M, Brown ST, Justice AC, Bryant KJ, Fiellin DA, Fiellin LE. Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial. AIDS And Behavior 2018, 23: 211-221. PMID: 30073637, PMCID: PMC6476298, DOI: 10.1007/s10461-018-2241-z.Peer-Reviewed Original ResearchConceptsHIV-positive patientsHeavy drinking daysVACS Index scoreXR-NTXART adherenceDrinking daysIndex scoreUndetectable HIV viral loadCD4 cell countExtended-release naltrexoneDouble-blind placeboHIV viral loadRandomized-controlled trialDrinking outcomesHIV biomarkersSecondary outcomesHIV outcomesPrimary outcomeViral loadAntiretroviral adherenceClinical trialsCell countAlcohol treatmentHIVPatients
2017
Customized Recommendations and Reminder Text Messages for Automated, Computer-Based Treatment During Methadone
Moore BA, Buono FD, Printz DMB, Lloyd DP, Fiellin DA, Cutter CJ, Schottenfeld RS, Barry DT. Customized Recommendations and Reminder Text Messages for Automated, Computer-Based Treatment During Methadone. Experimental And Clinical Psychopharmacology 2017, 25: 485-495. PMID: 29251978, PMCID: PMC5737744, DOI: 10.1037/pha0000149.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPatient engagementReminder messagesPreliminary efficacy findingsMethadone-maintained patientsSubstance use disordersIllicit drug useRandomized trialsEfficacy findingsMethadone maintenanceUse disordersPatient useDrug useSystem functionBehavioral therapyComputer-based interventionsPatientsShort latencyTotal call timeTrial 2Trial 1Line callsSelf-management systemCall timeTotal contact timeMultiple Sources of Prescription Payment and Risky Opioid Therapy Among Veterans
Becker WC, Fenton BT, Brandt CA, Doyle EL, Francis J, Goulet JL, Moore BA, Torrise V, Kerns RD, Kreiner PW. Multiple Sources of Prescription Payment and Risky Opioid Therapy Among Veterans. Medical Care 2017, 55: s33-s36. PMID: 28410338, DOI: 10.1097/mlr.0000000000000722.Peer-Reviewed Original ResearchConceptsOpioid therapySource of paymentHigher oddsHigh-dose opioid therapyHigh-risk opioid prescribingMorphine equivalent daily dosePayment sourceOpioid analgesic prescriptionsPrescription monitoring programsEquivalent daily doseCross-sectional studyAnalgesic prescriptionOpioid prescribingBenzodiazepine therapyDaily doseUS veteransFiscal year 2014TherapyPrivate insuranceLogistic regressionRelated harmsPrescription paymentAnalytic sampleOpioidsOddsEvaluation of an Integrated, Multidisciplinary Program to Address Unsafe Use of Opioids Prescribed for Pain
Becker WC, Edmond SN, Cervone DJ, Manhapra A, Sellinger JJ, Moore BA, Edens EL. Evaluation of an Integrated, Multidisciplinary Program to Address Unsafe Use of Opioids Prescribed for Pain. Pain Medicine 2017, 19: 1419-1424. PMID: 28371816, DOI: 10.1093/pm/pnx041.Peer-Reviewed Original ResearchConceptsPreliminary efficacyUnsafe useSubstance abuse/dependenceMultidisciplinary care teamSubstance use disorder diagnosisPrimary care physiciansAdvanced practice nursesUrine drug testingLength of treatmentStructured clinical assessmentNurse case managersAbuse/dependenceHealth system levelHigh-complexity patientsElectronic progress notesOpioid prescribedOpioid receiptCare physiciansPractice nursesPrimary careCare coordinationCare teamClinical assessmentCare modelClinic processes
2016
Interim Buprenorphine vs. Waiting List for Opioid Dependence
Sigmon SC, Ochalek TA, Meyer AC, Hruska B, Heil SH, Badger GJ, Rose G, Brooklyn JR, Schwartz RP, Moore BA, Higgins ST. Interim Buprenorphine vs. Waiting List for Opioid Dependence. New England Journal Of Medicine 2016, 375: 2504-2505. PMID: 28002704, PMCID: PMC5373028, DOI: 10.1056/nejmc1610047.Peer-Reviewed Original ResearchPrimary Care Physicians’ Willingness to Prescribe HIV Pre-exposure Prophylaxis for People who Inject Drugs
Edelman EJ, Moore BA, Calabrese SK, Berkenblit G, Cunningham C, Patel V, Phillips K, Tetrault JM, Shah M, Fiellin DA, Blackstock O. Primary Care Physicians’ Willingness to Prescribe HIV Pre-exposure Prophylaxis for People who Inject Drugs. AIDS And Behavior 2016, 21: 1025-1033. PMID: 27896552, PMCID: PMC5344709, DOI: 10.1007/s10461-016-1612-6.Peer-Reviewed Original ResearchConceptsPrimary care physiciansPre-exposure prophylaxisCare physiciansHIV pre-exposure prophylaxisHIV risk groupMore HIVClinic patientsRisk groupsGeneral internistsPWIDAcademic general internistsPractice characteristicsDisease preventionHIVPrEPProphylaxisPatientsPhysiciansCareDrugsOnline surveyInternistsHigher willingnessLower willingnessCentral roleA Cross-Sectional Online Survey of HIV Pre-Exposure Prophylaxis Adoption Among Primary Care Physicians
Blackstock OJ, Moore BA, Berkenblit GV, Calabrese SK, Cunningham CO, Fiellin DA, Patel VV, Phillips KA, Tetrault JM, Shah M, Edelman EJ. A Cross-Sectional Online Survey of HIV Pre-Exposure Prophylaxis Adoption Among Primary Care Physicians. Journal Of General Internal Medicine 2016, 32: 62-70. PMID: 27778215, PMCID: PMC5215171, DOI: 10.1007/s11606-016-3903-z.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHealth PersonnelHealth Risk BehaviorsHIV InfectionsHumansMaleMiddle AgedMultivariate AnalysisOdds RatioPractice Patterns, Physicians'Pre-Exposure ProphylaxisPrimary Health CareSurveys and QuestionnairesConceptsPrimary care physiciansHIV care experienceCare physiciansPrEP adoptionPrEP awarenessPractice characteristicsHIV pre-exposure prophylaxisCare experiencesAcademic primary care physiciansHIV-positive patientsPre-exposure prophylaxisHealth care providersResultsThe survey response rateSectional Online SurveyPCP adoptionHIV careKey ResultsThe survey response ratePercent of respondentsRisk compensationSurvey response ratePrEP knowledgePrEP useSelf-rated knowledgeMultivariable analysisClinical championsCognitive Behavioral Therapy Improves Treatment Outcomes for Prescription Opioid Users in Primary Care Buprenorphine Treatment
Moore BA, Fiellin DA, Cutter CJ, Buono FD, Barry DT, Fiellin LE, O'Connor PG, Schottenfeld RS. Cognitive Behavioral Therapy Improves Treatment Outcomes for Prescription Opioid Users in Primary Care Buprenorphine Treatment. Journal Of Substance Use And Addiction Treatment 2016, 71: 54-57. PMID: 27776678, PMCID: PMC5119533, DOI: 10.1016/j.jsat.2016.08.016.Peer-Reviewed Original ResearchConceptsOpioid-using patientsCognitive behavioral therapyUse patientsPhysician managementOpioid useTreatment outcomesBuprenorphine/naloxone treatmentHeroin use disorder patientsSelf-reported opioid useBehavioral therapyOpioid use groupPrevious drug treatmentUrine toxicology analysisEffects of CBTInjection drug useBaseline demographic differencesPrescription opioid usersBuprenorphine treatmentNaloxone treatmentOpioid abstinencePrescription opioidsOpioid usersOpioid categoryTreatment responseDrug treatmentStepped care model of pain management and quality of pain care in long-term opioid therapy
Moore BA, Anderson D, Dorflinger L, Zlateva I, Lee A, Gilliam W, Tian T, Khatri K, Ruser CB, Kerns RD. Stepped care model of pain management and quality of pain care in long-term opioid therapy. The Journal Of Rehabilitation Research And Development 2016, 53: 137-146. PMID: 27006068, DOI: 10.1682/jrrd.2014.10.0254.Peer-Reviewed Original Research