2023
Insights from immunoproteomic profiling of a rejected full-face transplant
Lee C, Wang D, Kauke-Navarro M, Russell-Goldman E, Xu S, Mucciarone K, Sohrabi S, Lian C, Pomahac B, Murphy G. Insights from immunoproteomic profiling of a rejected full-face transplant. American Journal Of Transplantation 2023, 23: 1058-1061. PMID: 37037378, DOI: 10.1016/j.ajt.2023.04.008.Peer-Reviewed Original ResearchConceptsVascularized Composite AllograftsT cellsChronic rejectionCD8-positive T cellsEffector T cellsFull face transplantArteriosclerotic alterationsIntragraft arteriesVCA rejectionGraft arteryAccelerated arteriosclerosisRecipient originPunch biopsyAtherogenic responseComposite allograftsImmunoproteomic profilingDioxygenase 1Target endotheliumArteryEndotheliumProteomic profilingPathway componentsCellsRejectionAllografts
2019
Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation
Shubin A, Kollar B, Dillon S, Pomahac B, Libermann T, Riella L. Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation. Scientific Data 2019, 6: 314. PMID: 31819064, PMCID: PMC6901551, DOI: 10.1038/s41597-019-0324-y.Peer-Reviewed Original ResearchMeSH KeywordsAptamers, NucleotideBiomarkersBlood ProteinsGraft RejectionHumansProteomeProteomicsTransplantationConceptsDevastating facial injuriesSevere rejection episodesAcute transplant rejectionType of transplantationPeripheral blood serumSOMAscan proteomics platformSatisfactory treatment optionAcute rejectionRejection episodesTransplant statusTransplantation centersTransplant rejectionTreatment optionsBiomarker discoverySkin biopsiesClinical dataHigh riskFacial injuriesInvasive biomarkersTransplantationAptamer-based technologiesFace transplantationPatientsBlood serumSerum proteins