2023
Surgical management of breast fat necrosis: Multi-institutional data analysis of early outcomes and risk factors for complications
Knoedler S, Knoedler L, Patel H, Diatta F, Camacho J, Sofo G, Perozzo F, Evans B, Mookerjee V, Ayyala H, Pomahac B, Kauke-Navarro M. Surgical management of breast fat necrosis: Multi-institutional data analysis of early outcomes and risk factors for complications. Journal Of Plastic Reconstructive & Aesthetic Surgery 2023, 88: 292-295. PMID: 38029475, DOI: 10.1016/j.bjps.2023.11.015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBreastFat NecrosisFemaleHeart FailureHumansMiddle AgedPatient ReadmissionPostoperative ComplicationsQuality ImprovementRetrospective StudiesRisk FactorsConceptsBreast fat necrosisChronic heart failureRisk factorsAdverse eventsHeart failureFemale patientsSurgical managementFat necrosisNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramHigher wound classPostoperative adverse eventsNon-cancerous conditionsOutcomes of interestQuality Improvement ProgramMajority of casesPerioperative algorithmWound classComplication occurrenceComplication ratePostoperative outcomesSurgical complicationsMedical complicationsSurgical treatmentMultivariable analysisThe surgical patient of yesterday, today, and tomorrow—a time-trend analysis based on a cohort of 8.7 million surgical patients
Knoedler S, Matar D, Friedrich S, Knoedler L, Haug V, Hundeshagen G, Kauke-Navarro M, Kneser U, Pomahac B, Orgill D, Panayi A. The surgical patient of yesterday, today, and tomorrow—a time-trend analysis based on a cohort of 8.7 million surgical patients. International Journal Of Surgery 2023, 109: 2631-2640. PMID: 37788019, PMCID: PMC10498871, DOI: 10.1097/js9.0000000000000511.Peer-Reviewed Original ResearchMeSH KeywordsAgedChild, PreschoolCluster AnalysisDatabases, FactualDiabetes Mellitus, Type 2HumansMiddle AgedObesityPostoperative ComplicationsConceptsSurgical patientsMedian ageMedian BMISurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseACS-NSQIP databaseImprovement Program databaseObesity class IProportion of patientsCohort of patientsPrevalence of diabetesType 2 diabetesGlobal healthcare deliveryFuture surgical careField of surgeryTime trend analysisPatient ageSurgical cohortDiabetes prevalenceProgram databaseSurgical careAmerican CollegeGeneral populationPatients
2022
Perioperative Outcomes and Risk Profile of 4730 Cosmetic Breast Surgery Cases in Academic Institutions: An ACS-NSQIP Analysis
Knoedler S, Kauke-Navarro M, Haug V, Broer P, Pomahac B, Knoedler L, Panayi A. Perioperative Outcomes and Risk Profile of 4730 Cosmetic Breast Surgery Cases in Academic Institutions: An ACS-NSQIP Analysis. Aesthetic Surgery Journal 2022, 43: 433-451. PMID: 36472232, DOI: 10.1093/asj/sjac320.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCosmetic breast surgeryObstructive pulmonary diseaseRisk factorsSurgical complicationsPulmonary diseaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMulti-institutional national databaseMultiple proceduresQuality Improvement Program databaseImprovement Program databaseIndependent risk factorCongestive heart failurePositive safety profileObesity class 1ACS-NSQIP AnalysisAnesthesiology scoreBreast surgery casesPerioperative outcomesPerioperative protocolPostoperative outcomesClinical patternHeart failureFemale patientsThe modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: An analysis of 40,415 cases
Panayi AC, Foroutanjazi S, Parikh N, Haug V, Kauke-Navarro M, Diehm YF, Pomahac B. The modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: An analysis of 40,415 cases. Journal Of Plastic Reconstructive & Aesthetic Surgery 2022, 75: 2941-2954. PMID: 35599223, DOI: 10.1016/j.bjps.2022.04.035.Peer-Reviewed Original ResearchMeSH KeywordsAgedFrailtyHumansMammaplastyPatient ReadmissionPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsConceptsImplant-based reconstructionBreast reconstructionMFI-5Unplanned readmissionPostoperative outcomesSurgical complicationsMedical complicationsMFI scoreRisk predictorsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseBreast reconstruction patientsFrailty index-5Powerful risk predictorImprovement Program databasePreoperative risk stratificationStrong risk predictorAutologous breast reconstructionAdverse surgical outcomesType of reconstructionHigh rateFrail patientsHospital stayPerioperative risk
2019
Five-Year Follow-up after Face Transplantation
Tasigiorgos S, Kollar B, Turk M, Perry B, Alhefzi M, Kiwanuka H, Nizzi M, Marty F, Chandraker A, Tullius S, Riella L, Pomahac B. Five-Year Follow-up after Face Transplantation. New England Journal Of Medicine 2019, 380: 2579-2581. PMID: 31141626, DOI: 10.1056/nejmc1810468.Peer-Reviewed Original ResearchMeSH KeywordsAdultFaceFacial TransplantationFollow-Up StudiesGraft RejectionHumansImmunosuppression TherapyInfectionsMiddle AgedPostoperative Complications
2018
Trismus in Face Transplantation Following Ballistic Trauma
Krezdorn N, Alhefzi M, Perry B, Aycart M, Tasigiorgos S, Bueno E, Green J, Pribaz J, Pomahac B, Caterson E. Trismus in Face Transplantation Following Ballistic Trauma. Journal Of Craniofacial Surgery 2018, 29: 843-847. PMID: 29381613, DOI: 10.1097/scs.0000000000004271.Peer-Reviewed Original ResearchMeSH KeywordsAdultFaceFacial TransplantationHumansMalePlastic Surgery ProceduresPostoperative ComplicationsRange of Motion, ArticularTrismusWounds, GunshotConceptsFace transplant recipientsTemporomandibular jointFace transplantationTransplant recipientsFunctional outcomeBallistic traumaMouth openingImpaired mouth openingOral food intakeImmediate postoperative periodBallistic injuriesRange of motionPartial face transplantationCovert injuriesIntraoperative releasePersistent trismusTotal condylectomyYear posttransplantPostoperative periodPostoperative planningPostoperative treatmentPrimary injuryIntraoperative evaluationSevere scarringMedical records
2017
Outcomes of Solid Organ Transplants After Simultaneous Solid Organ and Vascularized Composite Allograft Procurements
Aycart M, Alhefzi M, Sharma G, Krezdorn N, Bueno E, Talbot S, Carty M, Tullius S, Pomahac B. Outcomes of Solid Organ Transplants After Simultaneous Solid Organ and Vascularized Composite Allograft Procurements. Transplantation 2017, 101: 1381-1386. PMID: 27140518, PMCID: PMC6347371, DOI: 10.1097/tp.0000000000001262.Peer-Reviewed Original ResearchMeSH KeywordsAdultComposite Tissue AllograftsFacial TransplantationFemaleGraft SurvivalHumansMaleMiddle AgedOperative TimeOrgan TransplantationPostoperative ComplicationsRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTissue and Organ HarvestingTissue DonorsTreatment OutcomeUnited StatesYoung AdultConceptsGraft survival ratesSolid organsSurvival rateLiver recipientsTransplant recipientsAllograft procurementSolid organ allograftsSolid organ transplantsBrain-dead donorsLong-term outcomesShort-term resultsHeart recipientsIntraoperative parametersDonor surgeryOperative durationOrgan allograftsPostoperative outcomesScientific RegistryTransplantation outcomesPopulation of subjectsCase reportOperative characteristicsUnknown causeNationwide analysisOrgan transplants
2016
Rapid-Growing Mycobacteria Infections in Medical Tourists: Our Experience and Literature Review
Singh M, Dugdale C, Solomon I, Huang A, Montgomery M, Pomahac B, Yawetz S, Maguire J, Talbot S. Rapid-Growing Mycobacteria Infections in Medical Tourists: Our Experience and Literature Review. Aesthetic Surgery Journal 2016, 36: np246-np253. PMID: 27095310, DOI: 10.1093/asj/sjw047.Peer-Reviewed Original ResearchConceptsMycobacterial infectionRapid-growing mycobacteriaInfectious complicationsCosmetic surgeryUnusual infectious complicationAtypical mycobacterial infectionPatients' medical recordsElective cosmetic surgeryCosmetic surgical patientSurgical drainageSurgical patientsInitial presentationAtypical etiologyMean ageCombination antibioticsComplete resolutionMedical recordsMycobacteria infectionCorrect diagnosisInadequate sterilizationPatientsSurgeryMycobacterium abscessusSterile techniqueInfectionSurgical Optimization of Motor Recovery in Face Transplantation
Aycart M, Perry B, Alhefzi M, Bueno E, Kueckelhaus M, Fischer S, Pomahac B. Surgical Optimization of Motor Recovery in Face Transplantation. Journal Of Craniofacial Surgery 2016, 27: 286-292. PMID: 26967066, DOI: 10.1097/scs.0000000000002305.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolCleft LipCleft PalateCohort StudiesComorbidityCross InfectionFacial MusclesFacial NerveFacial TransplantationFemaleHospitals, PediatricHumansInfantInfant, NewbornMaleMotor NeuronsNerve TransferPlastic Surgery ProceduresPostoperative ComplicationsQuality ImprovementReoperationRetrospective StudiesRisk AdjustmentSmilingSurgical Wound InfectionConceptsMotor recoveryPatient 2Nerve transferNerve graftingPatient 1Devastating facial injuriesFacial nerve stumpFacial nerve reconstructionManual muscle testingFull face transplantIntraoperative soft tissueFacial nerve managementPrinciples of managementGradual improvementMuscle testingNerve reconstructionNerve stumpChallenging patientsMotor functionRetrospective analysisSensory restorationPatient's abilitySatisfactory motorFacial injuriesNerve managementA Mobile Extracorporeal Extremity Salvage System for Replantation and Transplantation
Kueckelhaus M, Fischer S, Sisk G, Kiwanuka H, Bueno E, Dermietzel A, Alhefzi M, Aycart M, Diehm Y, Pomahac B. A Mobile Extracorporeal Extremity Salvage System for Replantation and Transplantation. Annals Of Plastic Surgery 2016, 76: 355-360. PMID: 26808757, DOI: 10.1097/sap.0000000000000681.Peer-Reviewed Original ResearchConceptsMuscle damageLimb lossPerfusion deviceDeceased organ donorsIschemic muscle damageBilateral hind limbsPreferred treatmentBilateral limbsMuscle biopsyOrgan donorsTraumatic amputationHealthy limbPerfusion solutionReplantationArterial systemTransplantationHypoxic cellsPerfusate compositionHind limbPorcine limbsLimbSignificant differencesYorkshire pigsSalvage systemSimilar changes
2015
Transformation of Face Transplants: Volumetric and Morphologic Graft Changes Resemble Aging After Facial Allotransplantation
Kueckelhaus M, Turk M, Kumamaru K, Wo L, Bueno E, Lian C, Alhefzi M, Aycart M, Fischer S, De Girolami U, Murphy G, Rybicki F, Pomahac B. Transformation of Face Transplants: Volumetric and Morphologic Graft Changes Resemble Aging After Facial Allotransplantation. American Journal Of Transplantation 2015, 16: 968-978. PMID: 26639618, DOI: 10.1111/ajt.13544.Peer-Reviewed Original ResearchConceptsLong-term outcomesFacial allograftFacial allotransplantationSuperior long-term outcomesShort-term resultsRisk-benefit assessmentSoft tissue volumeSignificant volume lossTransplant recipientsVolume lossDiagnostic evaluationDonor selectionMuscle biopsyHistological evaluationComputed tomographyBone atrophyAllograftsFuture clinical routineNormal anatomyRecipient tissuesAllotransplantationClinical routineMorphometric changesSoft tissueMuscle fibers
2014
Functional Outcomes of Face Transplantation
Fischer S, Kueckelhaus M, Pauzenberger R, Bueno E, Pomahac B. Functional Outcomes of Face Transplantation. American Journal Of Transplantation 2014, 15: 220-233. PMID: 25359281, DOI: 10.1111/ajt.12956.Peer-Reviewed Original ResearchEarly Postoperative Imaging and Image-Guided Procedures on Patients with Face Transplants
Lee T, Chansakul T, Huang R, Wrubel G, Mukundan S, Annino D, Pribaz J, Pomahac B. Early Postoperative Imaging and Image-Guided Procedures on Patients with Face Transplants. American Journal Of Neuroradiology 2014, 36: 568-574. PMID: 25339651, PMCID: PMC8013040, DOI: 10.3174/ajnr.a4141.Peer-Reviewed Original ResearchMeSH KeywordsAdultEdemaFacial InjuriesFacial TransplantationFemaleHumansMiddle AgedPostoperative ComplicationsPostoperative PeriodRetrospective StudiesTomography, X-Ray ComputedConceptsPostoperative imagingImage-guided proceduresFace transplantationFluid collectionCommon postoperative findingEarly postoperative imagingLymph node biopsyManagement of complicationsPostoperative fluid collectionsNode biopsyPostoperative findingsFacial edemaConsecutive casesWomen's HospitalInvasive proceduresRetrospective evaluationTransplantationFace transplantComplicationsHospitalImagingLymphadenopathyEdemaPatientsBiopsyWound healing in acutely injured fascia
Lau F, Pomahac B. Wound healing in acutely injured fascia. Wound Repair And Regeneration 2014, 22: 14-17. PMID: 24813359, DOI: 10.1111/wrr.12165.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal MusclesFasciaFasciotomyHumansImmunohistochemistryPostoperative ComplicationsSkinSurgical Wound DehiscenceTensile StrengthWound HealingConceptsFascial healingIncisional herniaApparent functional deficitsSpecific surgical methodsFascial wound healingPaucity of dataHealing failureAcute injuryFunctional deficitsSurgical methodsSurgical proceduresSuch herniasMedical costsClinical settingHerniaClinical methodsFasciaWound healingHealingUnexpected findingRecent studiesSuch healingFailureCeliotomyPatients
2012
Infections Following Facial Composite Tissue Allotransplantation—Single Center Experience and Review of the Literature
Knoll B, Hammond S, Koo S, Issa N, Tullius S, Baden L, Pomahac B, Marty F. Infections Following Facial Composite Tissue Allotransplantation—Single Center Experience and Review of the Literature. American Journal Of Transplantation 2012, 13: 770-779. PMID: 23279299, DOI: 10.1111/ajt.12013.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Infective AgentsCatheter-Related InfectionsCytomegalovirusCytomegalovirus InfectionsFaceFemaleGraft RejectionGraft SurvivalHumansMaleMiddle AgedPneumoniaPostoperative ComplicationsPrognosisSurgical Wound InfectionTissue TransplantationTransplantation, HomologousTrimethoprim, Sulfamethoxazole Drug CombinationConceptsFacial composite tissue allotransplantationCMV diseaseInfectious complicationsPosttransplant infectionsClostridium difficile-associated diarrheaDiscontinuation of prophylaxisEarly posttransplant infectionsSurgical site infectionDifficile-associated diarrheaCatheter-associated infectionsComposite tissue allotransplantationInvasive dermatophyte infectionAdditional prophylaxisBacterial parotitisPerioperative prophylaxisValganciclovir treatmentCenter experienceProphylaxis strategiesSite infectionPolymicrobial bacteremiaRecipient factorsTrimethoprim-sulfamethoxazoleMedical recordsDermatophyte infectionsProphylaxisPredictors for Major Wound Complications Following Preoperative Radiotherapy and Surgery for Soft-Tissue Sarcoma of the Extremities and Trunk: Importance of Tumor Proximity to Skin Surface
Baldini E, Lapidus M, Wang Q, Manola J, Orgill D, Pomahac B, Marcus K, Bertagnolli M, Devlin P, George S, Abraham J, Ferrone M, Ready J, Raut C. Predictors for Major Wound Complications Following Preoperative Radiotherapy and Surgery for Soft-Tissue Sarcoma of the Extremities and Trunk: Importance of Tumor Proximity to Skin Surface. Annals Of Surgical Oncology 2012, 20: 1494-1499. PMID: 23242820, DOI: 10.1245/s10434-012-2797-1.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overDiabetes ComplicationsDisease-Free SurvivalFemaleHumansLower ExtremityMaleMiddle AgedNeoadjuvant TherapyNeoplasm Recurrence, LocalPostoperative ComplicationsRadiotherapy, AdjuvantSarcomaSkinSkin TransplantationSoft Tissue NeoplasmsSurgical FlapsTorsoUpper ExtremityWound HealingYoung AdultConceptsMajor wound complicationsSoft tissue sarcomasSplit-thickness skin graftPreoperative radiotherapyWound complicationsPostoperative radiotherapyMultivariable analysisTumor proximityExact testResultsMedian tumor sizeSimilar local controlOverall survival rateLong-term fibrosisSignificant predictorsFisher's exact testHigh rateNonoperative managementIndependent predictorsRadical resectionTumor sizeSkin surfaceUnivariate analysisSkin graftsComplicationsLocal control
2011
Face Transplantation
Pomahac B, Nowinski D, Diaz-Siso J, Bueno E, Talbot S, Sinha I, Westvik T, Vyas R, Singhal D. Face Transplantation. Current Problems In Surgery 2011, 48: 293-357. PMID: 21463717, DOI: 10.1067/j.cpsurg.2011.01.003.Peer-Reviewed Original ResearchDonor SelectionFacial TransplantationHumansPatient SelectionPlastic Surgery ProceduresPostoperative Complications
2007
The Role of Free-Tissue Transfer for Head and Neck Burn Reconstruction
Parrett B, Pomahac B, Orgill D, Pribaz J. The Role of Free-Tissue Transfer for Head and Neck Burn Reconstruction. Plastic & Reconstructive Surgery 2007, 120: 1871-1878. PMID: 18090749, DOI: 10.1097/01.prs.0000287272.28417.14.Peer-Reviewed Original ResearchConceptsFree flapBurn reconstructionTissue transferMean patient ageMedian hospital stayPercent of flapsMajority of flapsDonor site complicationsFree flap transferFree tissue transferReconstruction of headHospital stayPatient ageMain indicationsMinimal morbidityNeck burnsNecrosis rateAnterolateral thighHypertrophic scarringSecondary reconstructionRadial forearmFlap transferInfection rateLocal flapsCervicofacial burns