2005
Renal cell carcinoma: Current status and future prospects
Drucker BJ. Renal cell carcinoma: Current status and future prospects. Cancer Treatment Reviews 2005, 31: 536-545. PMID: 16236454, DOI: 10.1016/j.ctrv.2005.07.009.Peer-Reviewed Original ResearchConceptsAdvanced renal cell carcinomaRenal cell carcinomaTotal nephrectomyLocalized Renal Cell CarcinomaStandard systemic treatmentSubset of patientsMost patientsSystemic treatmentCurative treatmentRadical nephrectomyPoor prognosisCell carcinomaUnderlying pathophysiologyStandard treatmentRenal tumorsInvasive treatmentNew agentsTumor growthNephrectomyPatientsEarly detectionMolecular pathwaysSurgeryTreatmentDiagnostic methods
2002
Prognostic factors for biologic therapy in kidney cancer
Drucker BJ. Prognostic factors for biologic therapy in kidney cancer. Current Urology Reports 2002, 3: 31-36. PMID: 12084217, DOI: 10.1007/s11934-002-0008-5.Peer-Reviewed Original ResearchConceptsPrior nephrectomyCytokine therapyPrognostic factorsGood performance statusNormal lactate dehydrogenaseMajority of patientsLevels of cytokinesPresence of eosinophilsRenal cell cancerSubpopulations of lymphocytesLack of anemiaBiologic therapyPerformance statusImproved survivalCell cancerDisease characteristicsTumor responseNormal calciumImmune parametersInterleukin-2Kidney cancerTherapeutic benefitResponse rateTherapyLactate dehydrogenase