The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure
Maller Schulman BR, Liang X, Stahlhut C, DelConte C, Stefani G, Slack FJ. The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure. Cell Cycle 2008, 7: 3935-3942. PMID: 19098426, PMCID: PMC2895810, DOI: 10.4161/cc.7.24.7397.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGenes, LethalHeLa CellsHumansMiceMice, KnockoutMicroRNAsMutationNeural TubeTranscription FactorsConceptsLin-41Neural tube closureTube closureTerminal differentiationPrecocious cell cycle exitNematode Caenorhabditis elegansMore complex organismsCell cycle exitKey developmental eventsMicroRNA target genesNeural tube closure defectsLet-7 microRNACaenorhabditis elegansEpidermal skin cellsEmbryonic lethalityCycle exitComplex organismsTarget genesLet-7Developmental eventsDisease genesMouse mutantsClosure defectsMutantsFunctional role