2019
Dehydroepiandrosterone supplementation attenuates ovarian ageing in a galactose-induced primary ovarian insufficiency rat model
Sozen B, Ozekinci M, Erman M, Gunduz T, Demir N, Akouri R. Dehydroepiandrosterone supplementation attenuates ovarian ageing in a galactose-induced primary ovarian insufficiency rat model. Journal Of Assisted Reproduction And Genetics 2019, 36: 2181-2189. PMID: 31422495, PMCID: PMC6823469, DOI: 10.1007/s10815-019-01560-4.Peer-Reviewed Original ResearchConceptsPrimary ovarian insufficiencyDehydroepiandrosterone treatmentOvarian agingDecreased follicle numberReduced follicle poolPrimordial follicle recruitmentGalactose-containing dietOvarian follicle countsEffect of dehydroepiandrosteroneExpression of Ki67 proteinBody weightApoptosis marker expressionExpression of cleaved-caspase-3MethodsPregnant ratsOffspring ovariesFollicle poolOvarian insufficiencyFollicle countCell death assessmentFollicle recruitmentOvarian tissueIncreased atresiaKi67 proteinRat modelGroup 2
2014
Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries
Ozturk S, Sozen B, Demir N. Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries. Journal Of Assisted Reproduction And Genetics 2014, 32: 137-146. PMID: 25370180, PMCID: PMC4294878, DOI: 10.1007/s10815-014-0362-5.Peer-Reviewed Original ResearchConceptsPostnatal mouse ovariesCumulus-oocyte complexesMouse ovariesPABPC1 genePrepubertal ovariesGranulosa cellsGerm cellsPrepubertal mouse ovariesEarly preimplantation embryosOvarian follicle countsCytoplasm of oocytesRNA in situ hybridizationReal-time polymerase chain reactionVertebrate germ cellsExpression levelsMII oocytesOocyte complexesPostnatal ovaryCumulus cellsPreimplantation embryosFollicle countPABPC1 expressionQuantitative real-time polymerase chain reactionPolymerase chain reactionFollicular stage