2019
Dehydroepiandrosterone supplementation attenuates ovarian ageing in a galactose-induced primary ovarian insufficiency rat model
Sozen B, Ozekinci M, Erman M, Gunduz T, Demir N, Akouri R. Dehydroepiandrosterone supplementation attenuates ovarian ageing in a galactose-induced primary ovarian insufficiency rat model. Journal Of Assisted Reproduction And Genetics 2019, 36: 2181-2189. PMID: 31422495, PMCID: PMC6823469, DOI: 10.1007/s10815-019-01560-4.Peer-Reviewed Original ResearchConceptsPrimary ovarian insufficiencyDehydroepiandrosterone treatmentOvarian agingDecreased follicle numberReduced follicle poolPrimordial follicle recruitmentGalactose-containing dietOvarian follicle countsEffect of dehydroepiandrosteroneExpression of Ki67 proteinBody weightApoptosis marker expressionExpression of cleaved-caspase-3MethodsPregnant ratsOffspring ovariesFollicle poolOvarian insufficiencyFollicle countCell death assessmentFollicle recruitmentOvarian tissueIncreased atresiaKi67 proteinRat modelGroup 2
2012
Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain
Kencebay C, Derin N, Ozsoy O, Kipmen-Korgun D, Tanriover G, Ozturk N, Basaranlar G, Yargicoglu-Akkiraz P, Sozen B, Agar A. Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain. Food And Chemical Toxicology 2012, 52: 129-136. PMID: 23168241, DOI: 10.1016/j.fct.2012.11.015.Peer-Reviewed Original ResearchConceptsSomatosensory evoked potentialsSecretory phospholipase A2Quinacrine administrationS groupPlasma-S-sulfonate levelLatencies of SEP componentsMale albino Wistar ratsBrain TBARS levelsControl levelsTUNEL-positive cellsSQ groupTBARS levelsAlbino Wistar ratsSPLA2 levelsApoptotic cell deathGastric gavageSEP alterationsPositive cellsWistar ratsSEP componentsIntraperitoneal injectionRat brainCaspase-3RatsQuinacrine treatment