2016
The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia
Ozturk S, Sozen B, Uysal F, Bassorgun I, Usta M, Akkoyunlu G, Demir N. The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia. Journal Of Assisted Reproduction And Genetics 2016, 33: 335-348. PMID: 26843391, PMCID: PMC4785164, DOI: 10.1007/s10815-016-0654-z.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAzoospermiaBiopsyGene Expression RegulationHumansMaleMiddle AgedOligospermiaPoly(A)-Binding Protein IPoly(A)-Binding ProteinsSertoli Cell-Only SyndromeTestisConceptsPoly(A)-binding proteinNon-obstructive azoospermiaPoly(A)-binding protein geneSertoli cell-only syndromeTesticular biopsy samplesRound spermatidsPABP expressionExpression levelsIsolated spermatocytesTranslational controlProtein geneInfertile menPABPC1Male infertilitySpermatocytesPABPC3MRNA expressionArrest groupEPABSco groupBiopsy samplesMolecular backgroundProteinAzoospermiaEvaluate expression levels
2014
Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries
Ozturk S, Sozen B, Demir N. Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries. Journal Of Assisted Reproduction And Genetics 2014, 32: 137-146. PMID: 25370180, PMCID: PMC4294878, DOI: 10.1007/s10815-014-0362-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEmbryonic DevelopmentFemaleGene Expression Regulation, DevelopmentalHumansMiceOocytesOogenesisOvarian FolliclePoly(A)-Binding Protein IPoly(A)-Binding ProteinsConceptsPostnatal mouse ovariesCumulus-oocyte complexesMouse ovariesPABPC1 genePrepubertal ovariesGranulosa cellsGerm cellsPrepubertal mouse ovariesEarly preimplantation embryosOvarian follicle countsCytoplasm of oocytesRNA in situ hybridizationReal-time polymerase chain reactionVertebrate germ cellsExpression levelsMII oocytesOocyte complexesPostnatal ovaryCumulus cellsPreimplantation embryosFollicle countPABPC1 expressionQuantitative real-time polymerase chain reactionPolymerase chain reactionFollicular stageSuperovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos
Ozturk S, Yaba-Ucar A, Sozen B, Mutlu D, Demir N. Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos. Reproduction Fertility And Development 2014, 28: 375-383. PMID: 25034140, DOI: 10.1071/rd14106.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlastocystCells, CulturedChorionic GonadotropinDose-Response Relationship, DrugEmbryo Culture TechniquesFemaleFertility Agents, FemaleGene Expression Regulation, DevelopmentalGonadotropins, EquineMice, Inbred BALB COocytesOvulation InductionPoly(A)-Binding Protein IPoly(A)-Binding ProteinsSuperovulationTime FactorsConceptsEmbryonic poly(A)-binding proteinPregnant mare serum gonadotropinHuman chorionic gonadotrophinEarly embryo developmentAssisted reproductive technologyMII oocytesFemale miceAdministered to female miceGerminal vesicleOocyte maturationEmbryo developmentIncreased postimplantation lossDose of gonadotropinsCycling female miceDecreased implantation rateQuality of oocytesImpaired oocyte maturationGene expressionExperimental animal studiesEffects of superovulationReverse transcription-polymerase chain reactionPoly(A)-binding proteinPotential risk factorsTranscription-polymerase chain reactionImplantation rate
2012
Epab and Pabpc1 Are Differentially Expressed During Male Germ Cell Development
Ozturk S, Guzeloglu-Kayisli O, Demir N, Sozen B, Ilbay O, Lalioti MD, Seli E. Epab and Pabpc1 Are Differentially Expressed During Male Germ Cell Development. Reproductive Sciences 2012, 19: 911-922. PMID: 22814100, PMCID: PMC4046314, DOI: 10.1177/1933719112446086.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornGene Expression Regulation, DevelopmentalMaleMiceMice, Inbred C57BLPoly(A)-Binding Protein IPoly(A)-Binding ProteinsSpermatogenesisSpermatozoaTestisConceptsRound spermatidsGene expressionMale germ cell developmentGerm cell developmentPABPC1 expressionTranslational regulationCytoplasmic polyadenylationPosttranscriptional mechanismsPABPC1Key proteinsCell developmentEPABSpatial expressionMature testesMouse testisMessenger RNASpermatogenic cellsTail lengthProteinSpermatocytesExpressionSpermatogoniaTestisEarly postnatal lifePolyadenylation