2022
Visually sensitive seizures: An updated review by the Epilepsy Foundation
Fisher RS, Acharya JN, Baumer FM, French JA, Parisi P, Solodar JH, Szaflarski JP, Thio LL, Tolchin B, Wilkins AJ, Trenité D. Visually sensitive seizures: An updated review by the Epilepsy Foundation. Epilepsia 2022, 63: 739-768. PMID: 35132632, DOI: 10.1111/epi.17175.Peer-Reviewed Original ResearchConceptsPhotosensitive seizuresAntiseizure drugsPhotoparoxysmal responseEpilepsy FoundationPrevention of seizuresLight-induced seizuresWhite matter tractsSignificant public health hazardSpontaneous seizuresNonsystematic literature reviewGeneralized epilepsyPublic health hazardPhotosensitivity modelAbnormal connectivityOccipital cortexProvocative stimuliSeizuresVisual fieldVisual stimulationBrain imagingColor flashesUpdated reviewEpilepsySelection biasDrugs
2021
Antiseizure Medication Withdrawal in Seizure-Free Patients: Practice Advisory Update Summary
Gloss D, Pargeon K, Pack A, Varma J, French JA, Tolchin B, Dlugos DJ, Mikati MA, Harden C. Antiseizure Medication Withdrawal in Seizure-Free Patients: Practice Advisory Update Summary. Neurology 2021, 97: 1072-1081. PMID: 34873018, DOI: 10.1212/wnl.0000000000012944.Peer-Reviewed Original ResearchConceptsAntiseizure medicationsSeizure recurrenceSeizure freedomASM withdrawalPediatric patientsInsufficient evidenceAntiseizure medication withdrawalSeizure-free adultsSeizure-free patientsNeurology practice parameterSignificant differencesLong-term riskQuality of lifeMedication withdrawalStatus epilepticusEpilepsy surgeryPractice parametersRecurrencePatientsAmerican AcademyEpileptiform EEGMonthsWithdrawalAdultsRiskHow to do things with words Two seminars on the naming of functional (psychogenic, non-epileptic, dissociative, conversion, …) seizures
Wardrope A, Dworetzky BA, Barkley GL, Baslet G, Buchhalter J, Doss J, Goldstein LH, Hallett M, Kozlowska K, LaFrance WC, McGonigal A, Mildon B, Oto M, Perez DL, Riker E, Roberts NA, Stone J, Tolchin B, Reuber M. How to do things with words Two seminars on the naming of functional (psychogenic, non-epileptic, dissociative, conversion, …) seizures. Seizure 2021, 93: 102-110. PMID: 34740139, PMCID: PMC9308960, DOI: 10.1016/j.seizure.2021.10.016.Peer-Reviewed Original ResearchConceptsPsychogenic non-epileptic seizuresNon-epileptic attack disorderFunctional seizuresDissociative seizuresNon-epileptic seizuresAmerican Epilepsy SocietyHealth care systemNew diagnostic labelSynchronous electrical activityPatient responseDifferential diagnosisEpilepsy SocietyAttack disorderConversion disorderEpileptic seizuresSeizuresCare systemElectrical activityDiagnostic labelsDiagnosisDisordersEpilepsyPseudoseizuresBrainParoxysmsFunctional Seizures
Marcolini E, Tolchin B. Functional Seizures. Emergency Medicine Clinics Of North America 2021, 39: 123-132. PMID: 33218653, DOI: 10.1016/j.emc.2020.09.007.Peer-Reviewed Original ResearchConceptsFunctional seizuresEpileptic seizuresFunctional neurologic disordersElectroencephalography findingsPsychogenic seizuresTherapeutic challengeClinical historyEpileptic dischargesNeurologic disordersConversion disorderSeizuresMental illnessBiopsychosocial modelDisordersSocial factorsSymptomsIllness
2019
Motivational Interviewing Techniques to Improve Psychotherapy Adherence and Outcomes for Patients With Psychogenic Nonepileptic Seizures
Tolchin B, Baslet G, Martino S, Suzuki J, Blumenfeld H, Hirsch LJ, Altalib H, Dworetzky BA. Motivational Interviewing Techniques to Improve Psychotherapy Adherence and Outcomes for Patients With Psychogenic Nonepileptic Seizures. Journal Of Neuropsychiatry 2019, 32: 125-131. PMID: 31466516, DOI: 10.1176/appi.neuropsych.19020045.Peer-Reviewed Original ResearchMeSH KeywordsHumansMotivational InterviewingPatient CompliancePsychotherapySeizuresSomatoform DisordersConceptsPsychogenic nonepileptic seizuresClinician-patient communicationNonepileptic seizuresTreatment of PNESPoor clinician-patient communicationPatient-based barriersMajority of patientsFunctional neurological disorderEmergency medicine physiciansHealth care providersMotivational interviewing techniquesPsychiatric comorbidityTreatment nonadherenceTreatment existsCare providersMedicine physiciansPatient engagementPatientsNeurological disordersSomatic symptomsPatient ambivalenceTime-limited goalsPsychological therapiesHealth careTreatment planningTreatment of Patients With Psychogenic Nonepileptic Attacks
Tolchin B, Martino S, Hirsch LJ. Treatment of Patients With Psychogenic Nonepileptic Attacks. JAMA 2019, 321: 1967-1968. PMID: 31026015, DOI: 10.1001/jama.2019.3520.Peer-Reviewed Original ResearchRandomized controlled trial of motivational interviewing for psychogenic nonepileptic seizures
Tolchin B, Baslet G, Suzuki J, Martino S, Blumenfeld H, Hirsch LJ, Altalib H, Dworetzky BA. Randomized controlled trial of motivational interviewing for psychogenic nonepileptic seizures. Epilepsia 2019, 60: 986-995. PMID: 30980679, DOI: 10.1111/epi.14728.Peer-Reviewed Original ResearchConceptsPsychogenic nonepileptic seizuresQuality of lifeMI participantsPNES frequencyMotivational interviewingControl participantsNonepileptic seizuresQuaternary care medical centerEmergency department visitsEmergency department utilizationSingle neurologistDepartment visitsTreatment adherenceControl armMedical CenterMI armsSeizuresVisitsTrialsAdherenceParticipantsPsychotherapyAdherentArmReferralAdherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures.
Tolchin B, Dworetzky BA, Martino S, Blumenfeld H, Hirsch LJ, Baslet G. Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures. Neurology 2019, 92: e675-e679. PMID: 30610097, PMCID: PMC6382361, DOI: 10.1212/wnl.0000000000006848.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAdult Survivors of Child AbuseAgedAged, 80 and overCohort StudiesConversion DisorderEmergency Service, HospitalEthnicityFemaleFollow-Up StudiesHumansMaleMiddle AgedMinority GroupsOdds RatioProspective StudiesPsychotherapyQuality of LifeSeizuresTreatment Adherence and ComplianceTreatment OutcomeYoung AdultConceptsPsychogenic nonepileptic seizuresQuality of lifePNES frequencyNonepileptic seizuresProspective cohort studyEmergency department utilizationTime of referralBaseline characteristicsCohort studyED visitsSeizure frequencyED utilizationPotential confoundersWomen's HospitalTreatment outcomesMedium effect sizeLocal therapistsMultivariate modelAdherenceChildhood abuseSeizuresHospitalSignificant reductionOutcomesEffect size
2018
Naming things: Its importance in youth with epilepsy.
Hermann BP, Tolchin B. Naming things: Its importance in youth with epilepsy. Neurology 2018, 92: 13-14. PMID: 30518555, DOI: 10.1212/wnl.0000000000006680.Peer-Reviewed Original Research
2017
Long‐term adherence with psychiatric treatment among patients with psychogenic nonepileptic seizures
Tolchin B, Dworetzky BA, Baslet G. Long‐term adherence with psychiatric treatment among patients with psychogenic nonepileptic seizures. Epilepsia 2017, 59: e18-e22. PMID: 29218816, DOI: 10.1111/epi.13969.Peer-Reviewed Original ResearchConceptsBrief Illness Perception QuestionnairePsychogenic nonepileptic seizuresLong-term adherencePsychiatric treatmentPrior diagnosisNonepileptic seizuresCox proportional hazards regression analysisProportional hazards regression analysisProspective cohort studyHazards regression analysisFirst outpatient visitIllness Perception QuestionnairePercent of subjectsLower scoresCohort studyPsychiatric visitsOutpatient visitsVisit 2Risk factorsFourth visitOne's illnessSurvival analysisNonadherencePerception QuestionnairePatientsAssociation of Periodic and Rhythmic Electroencephalographic Patterns With Seizures in Critically Ill Patients
Ruiz A, Vlachy J, Lee JW, Gilmore EJ, Ayer T, Haider HA, Gaspard N, Ehrenberg JA, Tolchin B, Fantaneanu TA, Fernandez A, Hirsch LJ, LaRoche S. Association of Periodic and Rhythmic Electroencephalographic Patterns With Seizures in Critically Ill Patients. JAMA Neurology 2017, 74: 181-188. PMID: 27992625, DOI: 10.1001/jamaneurol.2016.4990.Peer-Reviewed Original ResearchConceptsRhythmic delta activityDelta activityPeriodic dischargesIll patientsSeizure riskElectroencephalographic patternsStimulation-induced patternsCritically Ill PatientsRisk of seizuresHigher seizure riskAcademic medical centerFrequency-dependent mannerSeizure incidenceIll adultsRisk stratificationHigh prevalenceMedical CenterMAIN OUTCOMEContinuous electroencephalographySeizuresPattern prevalenceMultivariate analysisPatientsClinical decisionRhythmic patterns