1988
Effects of apamin on the discharge properties of putative dopamine-containing neurons in vitro
Shepard P, Bunney B. Effects of apamin on the discharge properties of putative dopamine-containing neurons in vitro. Brain Research 1988, 463: 380-384. PMID: 3196925, DOI: 10.1016/0006-8993(88)90414-3.Peer-Reviewed Original ResearchConceptsDopamine-containing neuronsPutative dopamine-containing neuronsEffects of apaminCalcium-activated potassium conductanceCalcium-activated potassium channelsBrain slice preparationApamin administrationSubstantia nigraSlice preparationNeuronal excitabilityBursting activityPotassium conductancePotassium channelsNeuronsSelective inhibitorApaminRegular activitiesExcitabilityAdministrationNigra
1984
The control of firing pattern in nigral dopamine neurons: single spike firing
Grace A, Bunney B. The control of firing pattern in nigral dopamine neurons: single spike firing. Journal Of Neuroscience 1984, 4: 2866-2876. PMID: 6150070, PMCID: PMC6564731, DOI: 10.1523/jneurosci.04-11-02866.1984.Peer-Reviewed Original ResearchConceptsSingle-spike firingDA cellsSlow depolarizationCalcium chelator EGTADopamine neuronsSpike firingCalcium-activated potassium conductanceActive DA cellsNigral dopamine neuronsChelator EGTAVivo intracellular recordingsDA neuronsDepolarization inactivationMembrane potentialIontophoretic applicationTrain of spikesIntracellular recordingsExcitatory substancesIntracellular injectionCalcium entryAction potentialsAfterhyperpolarizationPotassium conductanceRate of riseNeuronsThe control of firing pattern in nigral dopamine neurons: burst firing
Grace A, Bunney B. The control of firing pattern in nigral dopamine neurons: burst firing. Journal Of Neuroscience 1984, 4: 2877-2890. PMID: 6150071, PMCID: PMC6564720, DOI: 10.1523/jneurosci.04-11-02877.1984.Peer-Reviewed Original ResearchConceptsDA cellsIntracellular injectionBase-line firing rateFiring ratePotassium conductanceIntracellular calcium injectionNigral dopamine neuronsStriatal DA releaseVivo intracellular recordingsBurst-firing modeDegree of burstDA releaseDopamine neuronsExtracellular iontophoresisBurst firingIntracellular recordingsCalcium injectionDopamine cellsCalcium influxCalcium involvementBursting patternInjectionCellsConsecutive spikesBlockade