1975
Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics.
Bunney B, Roth R, Aghajanian G. Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics. Psychopharmacology Communications 1975, 1: 349-58. PMID: 1224004.Peer-Reviewed Original ResearchConceptsEffects of molindoneCentral dopaminergic neuronal activityExtracellular single-unit recordingsLow intravenous dosesDopaminergic neuronal activityDA neuron activityMost antipsychotic drugsBaseline firing rateSingle-unit recordingsDA metabolismDA neuronsIntravenous dosesClassical neurolepticsDopaminergic neuronsOlfactory tubercleDA cellsAntipsychotic drugsD-amphetamineInduced depressionRat midbrainDopamine synthesisNeuronal activityUnit recordingsNeuron activityMolindone
1973
ELECTROPHYSIOLOGICAL EFFECTS OF AMPHETAMINE ON DOPAMINERGIC NEURONS
BUNNEY B, AGHAJANIAN G. ELECTROPHYSIOLOGICAL EFFECTS OF AMPHETAMINE ON DOPAMINERGIC NEURONS. 1973, 957-962. DOI: 10.1016/b978-0-08-017922-3.50182-9.Peer-Reviewed Original ResearchDA synthesisDopaminergic neuronsDA cellsElectrophysiological effectsD-AMPLow ejection currentsTyrosine hydroxylase inhibitorIntra-peritoneal administrationCell firing rateDA neuronsDA receptorsDepressant effectOlfactory tubercleEjection currentsIntravenous administrationCaudate nucleusHydroxylase inhibitorPostsynaptic cellFiring rateMinimal responseNeuronsBlockadeAntipsychotic phenothiazinesAdministrationAmphetamine