1980
Effects of baclofen on nigral dopaminergic cell activity following acute and chronic haloperidol treatment
Grace A, Bunney B. Effects of baclofen on nigral dopaminergic cell activity following acute and chronic haloperidol treatment. Brain Research Bulletin 1980, 5: 537-543. DOI: 10.1016/0361-9230(80)90087-8.Peer-Reviewed Original ResearchChronic haloperidol treatmentDopaminergic cell activityEffects of baclofenHaloperidol treatmentLow dosesExtracellular single-unit recording techniquesNeuroleptic-induced side effectsRat nigral dopaminergic neuronsCell activitySingle-unit recording techniquesInhibitory effectNigral DA cellsSingle low dosesNigral dopaminergic neuronsTreatment of spasticityAction of baclofenDose-response curveMechanism of actionDepolarization inactivationDopaminergic neuronsHaloperidol pretreatmentDA cellsPossible efficacyNigral inputsBaclofen
1979
EFFECTS OF CHRONIC HALOPERIDOL TREATMENT ON NIGRAL DOPAMINERGIC CELL ACTIVITY
Bunney B, Grace A. EFFECTS OF CHRONIC HALOPERIDOL TREATMENT ON NIGRAL DOPAMINERGIC CELL ACTIVITY. 1979, 666-668. DOI: 10.1016/b978-1-4832-8363-0.50202-0.Peer-Reviewed Original ResearchActive DA cellsChronic haloperidol treatmentDA cellsExtracellular single-unit recording techniquesRat nigral dopaminergic neuronsSingle-unit recording techniquesNigral dopaminergic neuronsNeurological side effectsEffects of chronicDepolarization inactivationHaloperidol treatmentDopaminergic neuronsExcitatory inputsSide effectsCell activityRecording techniquesPossible new mechanismSubsequent studiesTreatmentCellsAnimalsNigralChronicNeurons