1996
Effects of Lesions in the Medial Prefrontal Cortex on the Activity of Midbrain Dopamine Neurons
Shim S, Bunney B, Shi W. Effects of Lesions in the Medial Prefrontal Cortex on the Activity of Midbrain Dopamine Neurons. Neuropsychopharmacology 1996, 15: 437-441. PMID: 8914116, DOI: 10.1016/s0893-133x(96)00052-8.Peer-Reviewed Original ResearchConceptsVentral tegmental areaDA neuronsPrefrontal cortexSubstantia nigraPFC lesionsBursting activityFiring rateActive DA cellsSN DA neuronsActive DA neuronsMidbrain dopamine neuronsSingle-unit recordingsMedial prefrontal cortexDA cellsDopamine neuronsTegmental areaLocal injectionIbotenic acidUnit recordingsLesionsSame lesionNeuronsRatsActivityCortexRole of the Amygdala in the Coordination of Behavioral, Neuroendocrine, and Prefrontal Cortical Monoamine Responses to Psychological Stress in the Rat
Goldstein L, Rasmusson A, Bunney B, Roth R. Role of the Amygdala in the Coordination of Behavioral, Neuroendocrine, and Prefrontal Cortical Monoamine Responses to Psychological Stress in the Rat. Journal Of Neuroscience 1996, 16: 4787-4798. PMID: 8764665, PMCID: PMC6579011, DOI: 10.1523/jneurosci.16-15-04787.1996.Peer-Reviewed Original ResearchConceptsAmygdala lesionsMonoaminergic systemsMetabolic activationAdrenocortical activationStress-induced freezing behaviorStress-induced exacerbationStress-induced freezingPosttraumatic stress disorderAnteromedial prefrontal cortexNorepinephrine metabolismMonoamine responseAfferent controlNeuroendocrine componentBilateral NMDAPFC dopamineSchizophrenic symptomsCentral nucleusMild stressPrefrontal cortexStress disorderPsychological stressLesionsDopamineStress activationUltrasonic vocalizations
1980
Effect of sensory stimuli on the activity of dopaminergic neurons: Involvement of non-dopaminergic nigral neurons and striato-nigral pathways
Hommer D, Bunney B. Effect of sensory stimuli on the activity of dopaminergic neurons: Involvement of non-dopaminergic nigral neurons and striato-nigral pathways. Life Sciences 1980, 27: 377-386. PMID: 7412480, DOI: 10.1016/0024-3205(80)90185-x.Peer-Reviewed Original ResearchConceptsStriato-nigral pathwayDopaminergic neuronsReticulata neuronsInhibitory periodSingle-unit recording techniquesNon-dopaminergic neuronsNigro-striatal pathwaySciatic nerve stimulationRat substantia nigraDopaminergic neuron activitySensory stimuliInitial inhibitionStimulation-induced changesActivity of dopaminergicNigral neuronsNerve stimulationSubstantia nigraNeuron activityNeuronsRecording techniquesHaloperidolLesionsInhibitionStimulationPathway
1976
d-Amphetamine-Induced Inhibition of Central Dopaminergic Neurons: Mediation by a Striato-Nigral Feedback Pathway
Bunney B, Achajanian G. d-Amphetamine-Induced Inhibition of Central Dopaminergic Neurons: Mediation by a Striato-Nigral Feedback Pathway. Science 1976, 192: 391-393. PMID: 1257777, DOI: 10.1126/science.1257777.Peer-Reviewed Original ResearchConceptsD-amphetamineDepressant effectDopaminergic cell activityIntravenous d-amphetamineCentral dopaminergic neuronsStriato-nigral pathwayNeuronal feedback loopMicroiontophoretic applicationDopaminergic neuronsDopaminergic cellsCell activitySignificant slowingFeedback pathwaysPrevious dataCellsLesionsPathwayNeurons