1992
Roles of intracellular cAMP and protein kinase A in the actions of dopamine and neurotensin on midbrain dopamine neurons
Shi W, Bunney B. Roles of intracellular cAMP and protein kinase A in the actions of dopamine and neurotensin on midbrain dopamine neurons. Journal Of Neuroscience 1992, 12: 2433-2438. PMID: 1318960, PMCID: PMC6575923, DOI: 10.1523/jneurosci.12-06-02433.1992.Peer-Reviewed Original ResearchConceptsDopamine-induced inhibitionEffects of neurotensinDopamine neuronsIntracellular cAMPAdenylate cyclaseAction of neurotensinRat midbrain slicesAction of dopamineVentral tegmental areaMidbrain dopamine neuronsIntracellular cAMP levelsMidbrain slicesSubstantia nigraTegmental areaDopamine cellsDopamine effectsSpontaneous activityModulatory effectsNeurotensinIsobutyl methylxanthineInhibitory effectNeuronsCAMP levelsProtein kinase CInhibition
1991
Effects of neurotensin on midbrain dopamine neurons: Are they mediated by formation of a neurotensin—dopamine complex?
Shi W, Bunney B. Effects of neurotensin on midbrain dopamine neurons: Are they mediated by formation of a neurotensin—dopamine complex? Synapse 1991, 9: 157-164. PMID: 1776128, DOI: 10.1002/syn.890090302.Peer-Reviewed Original ResearchConceptsEffects of neurotensinNeurotensin receptorsDopamine neuronsDopamine cellsCell activitySingle-unit recording techniquesFiring rateMidbrain dopamine neuron activityAction of neurotensinBasal firing rateDopamine receptor blockadeDopamine-induced inhibitionDopamine neuron activityMidbrain dopamine neuronsReceptor blockadeDepolarization inactivationExcitatory effectsNative neurotensinBrain slicesNeuron activityNeurotensinNeurotensin analoguesSame receptorRecording techniquesReceptors