Cardiomyopathy in Congenital and Acquired Generalized Lipodystrophy
Lupsa BC, Sachdev V, Lungu AO, Rosing DR, Gorden P. Cardiomyopathy in Congenital and Acquired Generalized Lipodystrophy. Medicine 2010, 89: 245-250. PMID: 20616664, PMCID: PMC3090142, DOI: 10.1097/md.0b013e3181e9442f.Peer-Reviewed Original ResearchConceptsCohort of patientsGeneralized lipodystrophyCardiac findingsInsulin resistanceHypertrophic cardiomyopathyAcquired Generalized LipodystrophyLower leptin levelsExtreme insulin resistanceDiabetes mellitusLeptin therapyLeptin levelsSevere dyslipidemiaCardiac statusFrequent findingClinical trialsRare disorderPatientsAdipose tissueCardiomyopathyLipodystrophyCongenitalSeipin mutationsUnderlying mechanismPhenotypic featuresCohort