2016
Use of hyperspectral imaging to assess endothelial dysfunction in peripheral arterial disease
Sumpio BJ, Citoni G, Chin JA, Sumpio BE. Use of hyperspectral imaging to assess endothelial dysfunction in peripheral arterial disease. Journal Of Vascular Surgery 2016, 64: 1066-1073. PMID: 27266597, DOI: 10.1016/j.jvs.2016.03.463.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersBrachial ArteryCase-Control StudiesCoronary Artery DiseaseCross-Sectional StudiesEndothelium, VascularFemaleHemoglobinsHumansHyperemiaMaleMicrocirculationMiddle AgedMolecular ImagingOxyhemoglobinsPeripheral Arterial DiseasePilot ProjectsPredictive Value of TestsProspective StudiesReproducibility of ResultsSeverity of Illness IndexSkinSpectrum AnalysisUpper ExtremityVasodilationConceptsPeripheral artery diseaseCoronary artery diseaseCuff occlusionUpper armArtery diseaseVascular dysfunctionArterial diseasePresence of PADArterial disease patientsPeripheral arterial diseaseSystemic vascular dysfunctionAdvanced diseaseEndothelial dysfunctionVascular clinicProspective studySurgical historyControl cohortDisease patientsMedical recordsUpper extremityVascular bedHealthy volunteersPatientsHemoglobin concentrationDemographic data
1995
Endothelin-1 increases intracellular calcium in human monocytes and causes production of interleukin-6
McMillen M, Huribal M, Cunningham M, Kumar R, Sumpio B. Endothelin-1 increases intracellular calcium in human monocytes and causes production of interleukin-6. Critical Care Medicine 1995, 23: 34-40.. PMID: 8001384, DOI: 10.1097/00003246-199501000-00009.Peer-Reviewed Original ResearchConceptsEndothelin-1Intracellular calciumHuman monocytesIL-6Production of interleukinIL-6 productionIL-1 productionIntracellular calcium concentrationBasic science laboratoryM endothelinInterleukin-6Healthy donorsFura-2Control monocytesIschemic endotheliumMonocytesEndothelinCalcium concentrationMean valueCalciumTissue cultureInterleukinPhytohemagglutininEndotheliumEndotoxin
1994
Splenomegaly and variceal bleeding--hemodynamic basis and treatment implications.
Gusberg RJ, Peterec SM, Sumpio BE, Meier GH. Splenomegaly and variceal bleeding--hemodynamic basis and treatment implications. Hepatogastroenterology 1994, 41: 573-7. PMID: 7721248.Peer-Reviewed Original ResearchMeSH KeywordsBlood PressureEsophageal and Gastric VaricesFemaleGastrointestinal HemorrhageHepatic VeinsHumansHypertension, PortalLiver Cirrhosis, AlcoholicMaleMonitoring, IntraoperativePortal PressureProspective StudiesRadiographyRegional Blood FlowRetrospective StudiesSplenic VeinSplenomegalySplenorenal Shunt, SurgicalConceptsCirrhotic patientsPortal pressurePortal hypertensionSplenic embolizationVariceal bleedingHemodynamic basisSpleen sizeDistal splenorenal shuntPortal hypertensive patientsSplenic venous flowVariceal bleedersDefinitive therapyHypertensive patientsSplenorenal shuntSplenic enlargementSplenic veinVenous flowHemodynamic significancePatientsSplenomegalySplenic inflowTreatment implicationsHypertensionBleedingSplenectomy
1993
Captopril renal scintigraphy: A new standard for predicting outcome after renal revascularization
Meier G, Sumpio B, Setaro J, Black H, Gusberg R. Captopril renal scintigraphy: A new standard for predicting outcome after renal revascularization. Journal Of Vascular Surgery 1993, 17: 280-287. PMID: 8433423, DOI: 10.1016/0741-5214(93)90413-g.Peer-Reviewed Original ResearchConceptsCaptopril renal scintigraphyCaptopril-induced changesRenal revascularizationHypertension responseBlood pressureAmerican Heart Association criteriaDose of captoprilGlomerular filtration rateCessation of administrationNuclear medicine techniquesCaptopril administrationStandard renogramRenovascular diseaseBalloon angioplastyVascular toneRenal scintigraphyFiltration rateBaseline scanRevascularizationStudy groupAssociation criteriaPatientsEnzyme inhibitorsMedicine techniquesRenogram
1987
T-Lymphocyte Subsets in Renal Allograft Recipients Treated with Cyclosporine and Azathioprine
SUMPIO B, DWYER J, FLYE M. T-Lymphocyte Subsets in Renal Allograft Recipients Treated with Cyclosporine and Azathioprine. Annals Of Surgery 1987, 205: 49-53. PMID: 3541801, PMCID: PMC1492880, DOI: 10.1097/00000658-198701000-00009.Peer-Reviewed Original ResearchConceptsT4/T8 ratioRenal allograft recipientsT cell subsetsAntithymocyte globulinAllograft recipientsT8 ratioImmunosuppressive agentsPlasma levelsT lymphocytesNormal T4/T8 ratioDifferent immunosuppression protocolsT lymphocyte subsetsT4/T8Monoclonal antibody OKT3Cytomegalovirus titersImmunosuppression protocolsT4 subsetAntibody OKT3CyclosporinePatientsAzathioprineOnly azathioprineSelective ablationPrednisoneOKT3