2009
Polyphenols are medicine: Is it time to prescribe red wine for our patients?
Cordova A, Sumpio B. Polyphenols are medicine: Is it time to prescribe red wine for our patients? International Journal Of Angiology 2009, 18: 111-117. PMID: 22477510, PMCID: PMC2903024, DOI: 10.1055/s-0031-1278336.Peer-Reviewed Original ResearchLow physical activityNumerous epidemiological studiesVascular diseaseRisk factorsCardiovascular diseaseChronic pathologiesPhysical activityEpidemiological studiesModerate consumptionElevated smokingFrench paradoxRed wineHigh consumptionDiseaseHigh levelsPolyphenolsSmokingPatientsCancerMortalityPathologyPrevention
2005
Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis
Poussier B, Cordova AC, Becquemin JP, Sumpio BE. Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis. Journal Of Vascular Surgery 2005, 42: 1190-1190.e14. PMID: 16376213, DOI: 10.1016/j.jvs.2005.08.014.Peer-Reviewed Original ResearchMeSH KeywordsAngiogenesis InhibitorsAnimalsAnimals, NewbornAntioxidantsAorta, ThoracicApoptosisBlotting, WesternCattleCell ProliferationCells, CulturedDNADose-Response Relationship, DrugFlow CytometryIn Situ Nick-End LabelingIn Vitro TechniquesMuscle, Smooth, VascularProliferating Cell Nuclear AntigenResveratrolStilbenesConceptsSmooth muscle cell proliferationMuscle cell proliferationVascular smooth muscle cell proliferationDose-dependent mannerSMC proliferationCell proliferationG1-S phaseBeneficial effectsFrench paradoxDose-dependent apoptotic effectTerminal deoxynucleotidyl transferase-mediated dUTP-biotin nickTransferase-mediated dUTP-biotin nickCardiovascular death ratesRed wine intakeRed wine consumptionEffects of resveratrolAortic SMC proliferationEnd labeling stainingVascular SMC proliferationDUTP-biotin nickMajor polyphenol componentHealthy life styleCell cycle analysisCardiovascular mortalityFlow-activated cell sorting