2022
Heterogeneity in the guidelines for the management of diabetic foot disease in the Caribbean
Sumpio B, McConnie S, Maharaj D. Heterogeneity in the guidelines for the management of diabetic foot disease in the Caribbean. PLOS Global Public Health 2022, 2: e0000446. PMID: 36962244, PMCID: PMC10021831, DOI: 10.1371/journal.pgph.0000446.Peer-Reviewed Original ResearchDiabetic foot diseaseDF diseaseFoot diseaseMultidisciplinary teamLower extremity amputation ratesAmputation ratePodiatric careDiabetes mellitusSubsequent amputationInternational Working GroupVascular surgeryDiseaseHealth careMultidisciplinary approachDF problemMinority of countriesCareGuidelinesImplementation of strategiesCaribbean countriesStructured programWorking GroupRespondent countriesMellitusSurgery
2018
Radiotracer Imaging Allows for Noninvasive Detection and Quantification of Abnormalities in Angiosome Foot Perfusion in Diabetic Patients With Critical Limb Ischemia and Nonhealing Wounds
Alvelo JL, Papademetris X, Mena-Hurtado C, Jeon S, Sumpio BE, Sinusas AJ, Stacy MR. Radiotracer Imaging Allows for Noninvasive Detection and Quantification of Abnormalities in Angiosome Foot Perfusion in Diabetic Patients With Critical Limb Ischemia and Nonhealing Wounds. Circulation Cardiovascular Imaging 2018, 11: e006932. PMID: 29748311, PMCID: PMC5951395, DOI: 10.1161/circimaging.117.006932.Peer-Reviewed Original ResearchMeSH KeywordsAnkle Brachial IndexCase-Control StudiesCritical IllnessDiabetic FootHumansIschemiaMicrocirculationOrganophosphorus CompoundsOrganotechnetium CompoundsPerfusion ImagingPredictive Value of TestsRadiopharmaceuticalsRegional Blood FlowSingle Photon Emission Computed Tomography Computed TomographyWound HealingConceptsCritical limb ischemiaAnkle-brachial indexStandardized uptake valueSPECT/CT imagingDiabetic patientsHealthy subjectsSPECT/CTFoot perfusionUptake valueLimb ischemiaMicrovascular perfusionSkeletal muscle microvascular perfusionCT imagingDiabetic CLI patientsMuscle microvascular perfusionPeripheral artery diseaseSingle photon emissionIntraclass correlation coefficientAngiosome perfusionCLI subjectsCLI patientsArtery diseaseDiabetes mellitusCT perfusionVascular territories
2016
Wine, Polyphenols, and Cardioprotection
Sumpio B, Cordova A, Sumpio B. Wine, Polyphenols, and Cardioprotection. Nutrition And Health 2016, 97-108. DOI: 10.1007/978-3-319-27969-5_8.Peer-Reviewed Original Research
2015
Pulse volume recording for peripheral vascular disease diagnosis in diabetes patients
Sumpio B, Benitez E. Pulse volume recording for peripheral vascular disease diagnosis in diabetes patients. Journal Of Vascular Diagnostics And Interventions 2015, Volume 3: 33-39. DOI: 10.2147/jvd.s68048.Peer-Reviewed Original ResearchPulse volume recordingsPeripheral arterial diseaseArterial diseaseDisease processVolume recordingsDiabetes mellitusAnkle-brachial indexCritical limb ischemiaHigh-grade lesionsPatient's disease processNoninvasive vascular imagingPulse wave contourArterial duplexArterial etiologyBrachial indexLimb ischemiaDiabetic patientsClinical examinationDiabetes patientsPressure pulse waveformCompressible arteriesClinicians' knowledgePatientsVascular disease diagnosisVascular imaging
2013
Diabetes Mellitus and Peripheral Vascular Disease Diagnosis and Management
Chin JA, Sumpio BE. Diabetes Mellitus and Peripheral Vascular Disease Diagnosis and Management. Clinics In Podiatric Medicine And Surgery 2013, 31: 11-26. PMID: 24296015, DOI: 10.1016/j.cpm.2013.09.001.Peer-Reviewed Original ResearchConceptsPeripheral artery diseasePhysical examination findingsDifferent diagnostic modalitiesArtery diseaseDiabetes mellitusExamination findingsEndovascular interventionTreatment modalitiesDiagnostic modalitiesPathologic basisSame patientPrevalent diseaseVascular disease diagnosisNoninvasive studiesDiseaseMellitusDiagnosisModalitiesDisease diagnosisPatientsManagementA Comparison of Immediate Postoperative Rigid and Soft Dressings for Below-Knee Amputations
Sumpio B, Shine SR, Mahler D, Sumpio BE. A Comparison of Immediate Postoperative Rigid and Soft Dressings for Below-Knee Amputations. Annals Of Vascular Surgery 2013, 27: 774-780. PMID: 23880455, DOI: 10.1016/j.avsg.2013.03.007.Peer-Reviewed Original ResearchConceptsRigid dressingSoft dressingsDressing groupHealing timeYale-New Haven HospitalSoft dressing groupKaplan-Meier analysisBelow knee amputationEvidence-based guidelinesQuicker healing timeNew Haven HospitalInitial castingPlastic dressingEarly ambulationPatient demographicsDiabetes mellitusKnee amputationPostoperative dressingKnee immobilizerRetrospective analysisAverage agePatientsPostsurgical dressingsRigid plasterKnee amputees
2010
The Semmes Weinstein monofilament examination is a significant predictor of the risk of foot ulceration and amputation in patients with diabetes mellitus
Feng Y, Schlösser FJ, Sumpio BE. The Semmes Weinstein monofilament examination is a significant predictor of the risk of foot ulceration and amputation in patients with diabetes mellitus. Journal Of Vascular Surgery 2010, 53: 220-226.e5. PMID: 20692793, DOI: 10.1016/j.jvs.2010.06.100.Peer-Reviewed Original ResearchConceptsSemmes-Weinstein monofilament examinationLower extremity amputationDiabetes mellitusFoot ulcerationRelative riskMonofilament examinationDiabetic footPrognostic valueRisk of LEADiabetic peripheral neuropathyMEDLINE/PubMed databasePrognosis of patientsDiabetic foot ulcerationPublication date restrictionsEvidence-based toolsIndependent predictorsMajor complicationsPeripheral neuropathyPatient selectionExtremity amputationAbsolute riskDate restrictionsPrognostic studiesCurrent evidenceUlceration
2009
The Semmes Weinstein monofilament examination as a screening tool for diabetic peripheral neuropathy
Feng Y, Schlösser FJ, Sumpio BE. The Semmes Weinstein monofilament examination as a screening tool for diabetic peripheral neuropathy. Journal Of Vascular Surgery 2009, 50: 675-682.e1. PMID: 19595541, DOI: 10.1016/j.jvs.2009.05.017.Peer-Reviewed Original ResearchConceptsSemmes-Weinstein monofilament examinationDiabetic peripheral neuropathyNerve conduction studiesNegative predictive valuePositive predictive valueDiagnostic valueMonofilament examinationPeripheral neuropathyDiabetes mellitusPredictive valueLower extremity amputationRisk of ulcerationPublication date restrictionsCurrent literatureReference testConduction studiesExtremity amputationPlantar aspectDate restrictionsCurrent evidenceFifth metatarsalGreat toePubMed databaseEarly interventionIndependent investigators
2005
Review of Prevalence and Outcome of Vascular Disease in Patients with Diabetes Mellitus
Weiss JS, Sumpio BE. Review of Prevalence and Outcome of Vascular Disease in Patients with Diabetes Mellitus. European Journal Of Vascular And Endovascular Surgery 2005, 31: 143-150. PMID: 16203161, DOI: 10.1016/j.ejvs.2005.08.015.Peer-Reviewed Original ResearchConceptsLower extremity arterial diseaseLimb salvage rateExtremity arterial diseaseCarotid artery stenosisAbdominal aortic aneurysmMortality riskSalvage rateArterial diseaseArtery stenosisEquivalent mortality riskRisk of complicationsReview of prevalenceAAA prevalencePerioperative morbidityDiabetes mellitusGraft patencyUndergo surgeryAortic aneurysmEquivalent patencyVascular diseaseIncrease prevalenceMorbidity riskEquivalent prevalenceIncrease riskPatients
2004
Vascular Smooth Muscle Cell Migration: Current Research and Clinical Implications
Willis AI, Pierre-Paul D, Sumpio BE, Gahtan V. Vascular Smooth Muscle Cell Migration: Current Research and Clinical Implications. Vascular And Endovascular Surgery 2004, 38: 11-23. PMID: 14760473, DOI: 10.1177/153857440403800102.Peer-Reviewed Original ResearchConceptsVSMC migrationVascular smooth muscle cell migrationSmooth muscle cell migrationPotential therapeutic approachMuscle cell migrationDiabetes mellitusEndothelial injuryTherapeutic approachesIntimal hyperplasiaClinical implicationsMajor causeDevelopment of strategiesInjuryCell migrationMultiple stimuliHypertensionMellitusHyperlipidemiaMorbiditySmokingHyperplasiaMortality
2003
Charcot Joint Disease in Diabetes Mellitus
Lee L, Blume PA, Sumpio B. Charcot Joint Disease in Diabetes Mellitus. Annals Of Vascular Surgery 2003, 17: 571-580. PMID: 14508661, DOI: 10.1007/s10016-003-0039-5.Peer-Reviewed Original ResearchConceptsCharcot joint diseaseDiabetes mellitusJoint diseaseCharcot neuropathic arthropathyDiabetic foot ulcerationStructural foot deformitiesDevastating deformitiesNeuropathic arthropathyCharcot arthropathyDiabetic patientsFoot ulcerationClinical presentationDegenerative arthropathyPedal ulcerationFoot deformityFoot problemsTreatment modalitiesImmediate treatmentVascular surgeonsNeuropathic diseasePatientsMellitusArthropathyEarly signsStructural deformity
2000
Diabetic Vascular Disease: Biochemical and Molecular Perspectives
Kamal K, Chang R, Sumpio B. Diabetic Vascular Disease: Biochemical and Molecular Perspectives. 2000, 817-834. DOI: 10.1007/978-1-4612-1190-7_68.Peer-Reviewed Original ResearchDiabetes mellitusChronic complicationsMajor chronic complicationsEnd-organ damageCharacteristic pathological featuresDiscovery of insulinDiabetic patientsDiabetic angiopathyMetabolic abnormalitiesChronic hyperglycemiaPathological featuresVascular diseaseMellitusNatural historyComplicationsDiabetesPatientsAngiopathyMorbidityHyperglycemiaNerveKidneyMortalityAbnormalitiesInsulin
1993
Lipoprotein (a): A Risk Factor for Peripheral Vascular Disease
Widmann M, Sumpio B. Lipoprotein (a): A Risk Factor for Peripheral Vascular Disease. Annals Of Vascular Surgery 1993, 7: 446-451. PMID: 8268090, DOI: 10.1007/bf02002128.Peer-Reviewed Original ResearchConceptsPeripheral vascular diseaseCoronary artery diseaseDiabetes mellitusCigarette smokingRisk factorsCerebrovascular atherosclerotic diseaseWhite male patientArtery diseaseMale patientsAtherosclerotic diseasePlasma levelsVascular diseasePatientsDiseaseSerum proteinsMellitusComplicationsSmokingLipoprotein
1985
Results of Aortic Grafting in Occlusive vs Aneurysmal Disease
Sumpio B, Traquina D, Gusberg R. Results of Aortic Grafting in Occlusive vs Aneurysmal Disease. JAMA Surgery 1985, 120: 817-819. PMID: 4015373, DOI: 10.1001/archsurg.1985.01390310055012.Peer-Reviewed Original ResearchConceptsOcclusive diseaseAortic aneurysmAortic graftingOCC patientsSignificant intraoperative differenceSubsequent postoperative morbidityAtherosclerotic occlusive diseasePopulation of patientsDifferent patient groupsSignificant differencesRAA patientsAortic surgeryGraft surgeryPostoperative morbidityClamp timeSmoking historyDiabetes mellitusIntraoperative differencesPulmonary diseaseUrine outputFluid administrationAneurysmal diseaseAsymptomatic aneurysmsPatient groupRetrospective study