2019
Effects of Hypercholesterolemia and Statin Exposure on Survival in a Large National Cohort of Patients With Cirrhosis
Kaplan DE, Serper M, Mehta R, Fox R, John B, Aytaman A, Baytarian M, Hunt K, Albrecht J, Njei B, Taddei TH, Group V. Effects of Hypercholesterolemia and Statin Exposure on Survival in a Large National Cohort of Patients With Cirrhosis. Gastroenterology 2019, 156: 1693-1706.e12. PMID: 30660733, DOI: 10.1053/j.gastro.2019.01.026.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, HepatocellularCholesterolFemaleHeart FailureHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaLiver CirrhosisLiver NeoplasmsMaleMiddle AgedMyocardial InfarctionPropensity ScoreProportional Hazards ModelsRandomized Controlled Trials as TopicRetrospective StudiesStrokeSurvival RateUnited StatesConceptsRetrospective cohort studyStatin exposureLarge national cohortHepatic decompensationStatin useCohort studyHazard ratioNational cohortMultivariable Cox proportional hazards modelsCox proportional hazards modelBaseline total cholesterolPrior statin exposureStatin-naïve subjectsEffect of hypercholesterolemiaVeterans Health AdministrationProportional hazards modelHepatocellular carcinoma developmentDecrease of mortalityRisk-set matchingChild-TurcottePugh classStatin therapyDL increaseTotal cholesterolHepatic function
2018
Bariatric Surgery and Hepatocellular Carcinoma: a Propensity Score-Matched Analysis
Njei B, McCarty TR, Sharma P, Lange A, Najafian N, Ngu JN, Ngomba VE, Echouffo-Tcheugui JB. Bariatric Surgery and Hepatocellular Carcinoma: a Propensity Score-Matched Analysis. Obesity Surgery 2018, 28: 3880-3889. PMID: 30069863, PMCID: PMC6219901, DOI: 10.1007/s11695-018-3431-5.Peer-Reviewed Original ResearchMeSH KeywordsBariatric SurgeryCarcinoma, HepatocellularCross-Sectional StudiesHumansLiver NeoplasmsObesity, MorbidPropensity ScoreConceptsBariatric surgeryHepatocellular carcinomaPrevalence ratiosOdds ratioLow prevalenceUnited States Nationwide Inpatient Sample databaseNationwide Inpatient Sample databaseOccurrence of HCCPropensity scorePrior bariatric surgeryHospital mortality rateMorbidly obese patientsAge-adjusted prevalenceMortality odds ratioRisk of deathLength of stayCross-sectional associationsHospital mortalityMorbid obesityBaseline characteristicsObese patientsSecondary outcomesBackgroundThe associationPrimary outcomePatient mortality