Insulin and Cancer
Boyd D. Insulin and Cancer. Integrative Cancer Therapies 2003, 2: 315-329. PMID: 14713323, DOI: 10.1177/1534735403259152.Peer-Reviewed Original ResearchConceptsRole of insulinMetabolic syndromeIGF-1Insulin-like growth factor (IGF) systemGrowth factorChronic inflammatory stateTyrosine kinase growth factorsTypical Western dietGrowth factor systemInsulin-resistant statesLevels of obesityMajority of cancersTumor cell proliferationInsulin/insulin-like growth factor (IGF) systemImportant growth factorCytokine abnormalitiesStress-related changesInflammatory stateCancer outcomesInsulin resistanceWestern dietBreast cancerNeuroendocrine functionTumor progressionWeight gain