1996
Effects of Rapamycin on Ryanodine Receptor/Ca2+-Release Channels From Cardiac Muscle
Kaftan E, Marks A, Ehrlich B. Effects of Rapamycin on Ryanodine Receptor/Ca2+-Release Channels From Cardiac Muscle. Circulation Research 1996, 78: 990-997. PMID: 8635249, DOI: 10.1161/01.res.78.6.990.Peer-Reviewed Original ResearchConceptsRelease channelFK506-binding proteinCardiac muscleLong-term depressionEffect of rapamycinChannel functionProlyl isomerase activityRelease of Ca2Ryanodine receptor/Ca2Immunosuppressant drugsSkeletal muscle isoformCardiac RyRIsomerase activityRyanodine receptorRapamycinRyRsChannel familyImportant regulatory roleCis-trans peptidylOpen probabilitySubmicromolar concentrationsCell typesDrugsMuscleMuscle isoform
1991
Comparison of calcium release from sarcoplasmic reticulum of slow and fast twitch muscles
Lee Y, Ondrias K, Duhl A, Ehrlich B, Kim D. Comparison of calcium release from sarcoplasmic reticulum of slow and fast twitch muscles. The Journal Of Membrane Biology 1991, 122: 155-163. PMID: 1716686, DOI: 10.1007/bf01872638.Peer-Reviewed Original ResearchConceptsFast sarcoplasmic reticulumFast-twitch muscleSarcoplasmic reticulumRelease channelSlow sarcoplasmic reticulumTwitch muscleFast musclesSR vesiclesTypes of muscleCalcium releaseMechanism of Ca2MuscleScatchard analysisRyanodine receptorFunctional assaysRuthenium redSingle Ca2Single-channel conductanceOpen probabilityMolecular weight proteinsCa2Closed timeHigh molecular weight proteinsFunctional differences
1990
Comparison of calcium release channels in reticular membranes from smooth muscle, skeletal muscle and cerebellum
Watras J, Adler P, Ondrias K, Ehrlich B. Comparison of calcium release channels in reticular membranes from smooth muscle, skeletal muscle and cerebellum. Journal Of Molecular And Cellular Cardiology 1990, 22: s9. DOI: 10.1016/0022-2828(90)91336-6.Peer-Reviewed Original Research
1984
Lithium concentration in the muscle compartment of manic-depressive patients during lithium therapy
Ehrlich B, Clausen C, Gosenfeld L, Diamond J. Lithium concentration in the muscle compartment of manic-depressive patients during lithium therapy. Journal Of Psychiatric Research 1984, 18: 139-148. PMID: 6747912, DOI: 10.1016/0022-3956(84)90005-0.Peer-Reviewed Original ResearchConceptsSide effectsComparison of patientsManic-depressive patientsEffects of lithiumLithium therapyTherapeutic responseRenal excretionPlasma ratioIntestinal absorptionNormal controlsWarrants evaluationMuscle compartmentsTherapyPharmacokinetic techniquesRBC ratioPatientsObserved musclesMuscleBody compartmentsHuman muscleExcitable cellsRBCsExcretionConcentration ratioLithium concentration