2023
Botulinum Toxin Treatment for Cancer-Related Disorders: A Systematic Review
Safarpour D, Jabbari B. Botulinum Toxin Treatment for Cancer-Related Disorders: A Systematic Review. Toxins 2023, 15: 689. PMID: 38133193, PMCID: PMC10748363, DOI: 10.3390/toxins15120689.Peer-Reviewed Original ResearchConceptsBoNT injectionsFacial sweatingCancer-related disordersParotid regionSystematic reviewComplication of parotidectomySevere jaw painBotulinum toxin treatmentParotid gland surgeryBotulinum neurotoxin therapyCessation of painSerious side effectsSite of surgeryBoNT effectsGustatory hyperhidrosisJaw painNeurotoxin therapySteroid injectionLocal resectionEsophageal strictureSurgical approachEsophageal cancerLocal injectionSaline injectionToxin treatment
2018
Botulinum Toxin in Restless Legs Syndrome—A Randomized Double-Blind Placebo-Controlled Crossover Study
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum Toxin in Restless Legs Syndrome—A Randomized Double-Blind Placebo-Controlled Crossover Study. Toxins 2018, 10: 401. PMID: 30274305, PMCID: PMC6215171, DOI: 10.3390/toxins10100401.Peer-Reviewed Original ResearchConceptsRestless legs syndromePain scoresCrossover studyLegs syndromePlacebo-controlled crossover studyDouble-blind placeboPatient Global ImpressionVisual analog scalePrevious smaller studiesCommon movement disorderQuality of lifeIncobotulinumtoxin APlacebo groupRLS symptomsAnalog scaleGlobal ImpressionOnabotulinumtoxin ALife QuestionnaireTibialis anteriorBotulinum toxinNormal salineMovement disordersRLS scoresSmall studyFemoris muscleBotulinum toxin in essential hand tremor - A randomized double-blind placebo-controlled study with customized injection approach
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum toxin in essential hand tremor - A randomized double-blind placebo-controlled study with customized injection approach. Parkinsonism & Related Disorders 2018, 56: 65-69. PMID: 29929813, DOI: 10.1016/j.parkreldis.2018.06.019.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBotulinum Toxins, Type ACross-Over StudiesDouble-Blind MethodEssential TremorFemaleHandHumansMaleMiddle AgedNeuromuscular AgentsTreatment OutcomeConceptsHand weaknessEssential hand tremorDouble-blind placebo-controlled studyEssential tremorAdministration of onabotulinumtoxinASevere hand weaknessPlacebo-controlled studyClinical rating scoresHand tremorRating scoresParkinson's disease tremorIncobotulinumtoxinA injectionsCrossover trialPatients' perceptionsBotulinum toxinTreatment efficacyClinical practiceHand strengthForearm musclesTremor severityClinical scalesTremorWeeksTreatmentInjection
2017
Botulinum Toxin in Parkinson Disease Tremor A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach
Mittal SO, Machado D, Richardson D, Dubey D, Jabbari B. Botulinum Toxin in Parkinson Disease Tremor A Randomized, Double-Blind, Placebo-Controlled Study With a Customized Injection Approach. Mayo Clinic Proceedings 2017, 92: 1359-1367. PMID: 28789780, DOI: 10.1016/j.mayocp.2017.06.010.Peer-Reviewed Original ResearchConceptsDisease Rating ScaleHand weaknessPatients' perceptionsUnified Parkinson's Disease Rating ScaleParkinson's Disease Rating ScaleAdministration of onabotulinumtoxinASevere hand weaknessUse of onabotulinumtoxinAPatient Global ImpressionClinical rating scoresTreatment of tremorParkinson's disease tremorIncobotulinumtoxinA injectionsCrossover trialGlobal ImpressionGrip strengthRest tremorBotulinum toxinPD tremorPostural tremorTreatment efficacyClinical practiceSignificant improvementEssential tremorHand strength
2016
Abobotulinum Toxin A in the Treatment of Chronic Low Back Pain
Machado D, Kumar A, Jabbari B. Abobotulinum Toxin A in the Treatment of Chronic Low Back Pain. Toxins 2016, 8: 374. PMID: 27983689, PMCID: PMC5198568, DOI: 10.3390/toxins8120374.Peer-Reviewed Original ResearchConceptsChronic low back painLow back painVisual analog scaleOswestry Low Back Pain Disability QuestionnaireAbobotulinum toxin ABack painQuality of lifeToxin APain Disability QuestionnairePatient Global ImpressionLevel of painPrimary outcome measureProportion of respondersStrong analgesic effectAbobotulinum toxinOswestry scorePlacebo groupAnalgesic effectDisability QuestionnaireMore patientsStudy cohortAnalog scaleGlobal ImpressionMultifactorial pathophysiologyPatients' perceptionsBotulinum Toxin Treatment of Neuropathic Pain
Mittal SO, Safarpour D, Jabbari B. Botulinum Toxin Treatment of Neuropathic Pain. Seminars In Neurology 2016, 36: 073-083. PMID: 26866499, DOI: 10.1055/s-0036-1571953.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholine Release InhibitorsAnalgesicsBotulinum ToxinsBotulinum Toxins, Type ADiabetic NeuropathiesFemaleHumansMiddle AgedNeuralgiaTreatment OutcomeConceptsNeuropathic painBoNT treatmentComplex regional pain syndromeBotulinum toxin treatmentPainful diabetic neuropathyRegional pain syndromeCarpal tunnel syndromePhantom limb painEvidence-based statementsForm of painTechnique of injectionPosttraumatic neuralgiaAnalgesic medicationPain syndromePostherpetic neuralgiaDiabetic neuropathyOccipital neuralgiaLevel of efficacyLimb painTrigeminal neuralgiaTunnel syndromeClinical trialsToxin treatmentPainNeuralgiaIncobotulinum Toxin-A Improves Post-Surgical and Post-Radiation Pain in Cancer Patients
Rostami R, Mittal SO, Radmand R, Jabbari B. Incobotulinum Toxin-A Improves Post-Surgical and Post-Radiation Pain in Cancer Patients. Toxins 2016, 8: 22. PMID: 26771640, PMCID: PMC4728544, DOI: 10.3390/toxins8010022.Peer-Reviewed Original ResearchConceptsVisual analog scaleCancer patientsGlobal ImpressionSite of radiationPoor general conditionPatient Global ImpressionLocation of painIncobotulinum toxin AFocal painAnalgesic medicationPain controlAnalog scaleSkin reactionsToxin ALocal cancerPatientsSignificant improvementPainSurgeryChange ScaleResearch protocolSignificant satisfactionGeneral conditionMedicationsFollow
2013
Hyperhidrosis: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins
Lakraj AA, Moghimi N, Jabbari B. Hyperhidrosis: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins. Toxins 2013, 5: 821-840. PMID: 23612753, PMCID: PMC3705293, DOI: 10.3390/toxins5040821.Peer-Reviewed Original ResearchMeSH KeywordsBotulinum ToxinsBotulinum Toxins, Type ADermatologic AgentsEvidence-Based MedicineHumansHyperhidrosisInjections, IntradermalIontophoresisSweat GlandsConceptsClass II studiesII studyAxillary hyperhidrosisPalmar hyperhidrosisComparator studiesBotulinum toxinClass IEvidence level BLevel of evidenceClass III studiesOral agentsIII studyClinical featuresTopical agentsComparable efficacyLong lasting effectInjection sessionsBlinded studyAmerican AcademyDrug efficacyClass IIHyperhidrosisEfficacyWorld literatureToxin
2012
OnabotulinumtoxinA for Treatment of Focal Cancer Pain After Surgery and/or Radiation
Mittal S, Machado DG, Jabbari B. OnabotulinumtoxinA for Treatment of Focal Cancer Pain After Surgery and/or Radiation. Pain Medicine 2012, 13: 1029-1033. PMID: 22776097, DOI: 10.1111/j.1526-4637.2012.01437.x.Peer-Reviewed Original ResearchConceptsQuality of lifeCancer patientsCancer painLocal treatmentEffect of onabotulinumtoxinAPatient global assessmentAreas of surgeryFocal painMasseter injectionLocal surgeryPain reliefPain areaRepeat injectionsRepeat treatmentPainPatientsSecond injectionSignificant improvementOnabotulinumtoxinAGlobal assessmentSurgeryJaw musclesTreatmentInjectionRelief
2011
Treatment of Refractory Pain with Botulinum Toxins—An Evidence-Based Review
Jabbari B, Machado D. Treatment of Refractory Pain with Botulinum Toxins—An Evidence-Based Review. Pain Medicine 2011, 12: 1594-1606. PMID: 21958302, DOI: 10.1111/j.1526-4637.2011.01245.x.Peer-Reviewed Original ResearchConceptsPost-operative painRefractory painBotulinum toxinChronic low back painChronic lateral epicondylitisClass II articlesLevel B evidenceLevel C evidencePost-traumatic neuralgiaVastus lateralis imbalanceMyofascial pain syndromePlacebo-controlled studyPost-herpetic neuralgiaAnterior knee painPainful knee osteoarthritisChronic daily headacheLow back painTotal knee arthroplastyEvidence-based reviewEvidence-based dataSphincter spasmKnee painPain syndromePelvic painPiriformis syndrome
2010
Botulinum Toxin A for Treatment of Allodynia of Complex Regional Pain Syndrome: A Pilot Study
Safarpour D, Salardini A, Richardson D, Jabbari B. Botulinum Toxin A for Treatment of Allodynia of Complex Regional Pain Syndrome: A Pilot Study. Pain Medicine 2010, 11: 1411-1414. PMID: 20609130, DOI: 10.1111/j.1526-4637.2010.00897.x.Peer-Reviewed Original ResearchConceptsComplex regional pain syndromeRegional pain syndromeBotulinum toxin APain syndromeToxin AOpen-label protocolPain Impact QuestionnairePlacebo-controlled protocolTreatment of allodyniaBrief Pain InventoryMcGill Pain QuestionnaireGlobal satisfaction scaleAllodynic areaAllodynic skinPain InventoryPain QuestionnaireImpact QuestionnaireSubcutaneous administrationPatientsSatisfaction ScaleAllodyniaPilot studySyndromeBoNTTreatmentBotulinum Toxin A (Botox) for Treatment of Proximal Myofascial Pain in Complex Regional Pain Syndrome: Two Cases
Safarpour D, Jabbari B. Botulinum Toxin A (Botox) for Treatment of Proximal Myofascial Pain in Complex Regional Pain Syndrome: Two Cases. Pain Medicine 2010, 11: 1415-1418. PMID: 20735753, DOI: 10.1111/j.1526-4637.2010.00929.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBotulinum Toxins, Type AComplex Regional Pain SyndromesFemaleHumansMiddle AgedMyofascial Pain SyndromesNeurotoxinsTreatment OutcomeConceptsMyofascial pain syndromeComplex regional pain syndromeAdministration of BoNTRegional pain syndromeBotulinum toxin APain syndromeTrigger pointsProximal musclesDistal symptomsToxin AMuscle trigger pointsPainful trigger pointsUpper back musclesCarpal tunnel syndromeProximal painSevere allodyniaCRPS-1Myofascial painForearm injuriesSuch patientsRight trapeziusTunnel syndromePainful limbSplenius capitisSuccessful treatment
2009
Botulinum Neurotoxin-A for Treatment of Refractory Neck Pain: A Randomized, Double-Blind Study
Miller D, Richardson D, Eisa M, Bajwa RJ, Jabbari B. Botulinum Neurotoxin-A for Treatment of Refractory Neck Pain: A Randomized, Double-Blind Study. Pain Medicine 2009, 10: 1012-1017. PMID: 19594841, DOI: 10.1111/j.1526-4637.2009.00658.x.Peer-Reviewed Original ResearchConceptsVisual analog scaleRefractory neck painNeck painExcellent respondersPrimary outcomeMean visual analog scaleAdministration of BoNTEfficacy of BoNTUnits of BoNTChronic neck painPlacebo-controlled studyDouble-blind studyImprovement of ADLBotulinum neurotoxinPlacebo groupAnalgesic effectBotox groupFrequency questionnaireSecondary outcomesPain intensityPain localizationPain QuestionnaireAnalog scaleBlinded studyAnimal studies
2008
Relief of Intractable Pruritus After Administration of Botulinum Toxin A (Botox)
Salardini A, Richardson D, Jabbari B. Relief of Intractable Pruritus After Administration of Botulinum Toxin A (Botox). Clinical Neuropharmacology 2008, 31: 303-306. PMID: 18836352, DOI: 10.1097/wnf.0b013e3181672225.Peer-Reviewed Original ResearchTreatment of Painful Limbs/Moving Extremities with Botulinum Toxin Type A Injections
Eisa M, Singer C, Sengun C, Russel A, Jabbari B, Papapetropoulos S. Treatment of Painful Limbs/Moving Extremities with Botulinum Toxin Type A Injections. European Neurology 2008, 60: 104-106. PMID: 18552499, DOI: 10.1159/000138962.Peer-Reviewed Original Research