2001
Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus
Sozen I, Senturk L, Arici A. Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus. Fertility And Sterility 2001, 76: 792-796. PMID: 11591415, DOI: 10.1016/s0015-0282(01)02378-0.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1Leiomyomatous uterusMacrophage countGonadotropin-releasing hormone agonistDirect paracrine effectChemotactic protein-1 productionMCP-1 levelsChemotactic protein-1MCP-1 stainingCross-sectional studyMyometrium of womenMCP-1 expressionMonocyte chemotactic protein-1 productionMCP-1 protein expressionUniversity Medical CenterProtein-1 productionGnRH agonistHormone agonistMacrophage infiltrationMedical CenterMAIN OUTCOMEImmunohistochemical analysisLeiomyoma cellsParacrine effectsGnRHExpression of aminopeptidase N in human endometrium and regulation of its activity by estrogen
Seli E, Senturk L, Bahtiyar O, Kayisli U, Arici A. Expression of aminopeptidase N in human endometrium and regulation of its activity by estrogen. Fertility And Sterility 2001, 75: 1172-1176. PMID: 11384645, DOI: 10.1016/s0015-0282(01)01779-4.Peer-Reviewed Original ResearchConceptsExpression of APNEarly proliferative phaseMenstrual cycleInterleukin-8Human endometriumProliferative phaseCultured endometrial stromal cellsEndometrial stromal cell culturesEndometrial stromal cellsUniversity Medical CenterPolymorphonuclear leukocyte chemotaxisAPN activityAminopeptidase NConcentration-dependent mannerEndometrial pathologyEndometrial stromaProspective studyStromal cell culturesEndometrial sectionsAPN antibodyMedical CenterMAIN OUTCOMESex steroidsSecretory phaseEndometrium
2000
Transforming growth factor-β3 is expressed at high levels in leiomyoma where it stimulates fibronectin expression and cell proliferation
Arici A, Sozen I. Transforming growth factor-β3 is expressed at high levels in leiomyoma where it stimulates fibronectin expression and cell proliferation. Fertility And Sterility 2000, 73: 1006-1011. PMID: 10785229, DOI: 10.1016/s0015-0282(00)00418-0.Peer-Reviewed Original ResearchConceptsTGF-beta3 mRNA levelsLeiomyoma cell proliferationCell proliferationLeiomyoma cellsFibronectin expressionMRNA levelsLeiomyoma samplesProliferative phase samplesTGF-beta3 mRNAUniversity Medical CenterFibronectin mRNA expressionExpression of fibronectinMedical CenterFibrogenic processMAIN OUTCOMESex steroidsMidsecretory phaseMyometrial cellsMyometrial samplesLeiomyomaTGF-beta3MRNA expressionGrowth-promoting effectMyometriumGrowth factor β3
1998
Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization–embryo transfer
Zeyneloglu H, Arici A, Olive D. Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization–embryo transfer. Fertility And Sterility 1998, 70: 492-499. PMID: 9757878, DOI: 10.1016/s0015-0282(98)00200-3.Peer-Reviewed Original ResearchConceptsIVF-ETOdds ratioPregnancy rateClinical pregnancy rateFertilization-embryo transferEffect of hydrosalpinxUniversity Medical CenterEstablishment of pregnancyClinical pregnancyImplantation rateET cyclesPregnancy lossHydrosalpinxMedical CenterMAIN OUTCOMEAbortion rateAdverse effectsReduced chanceConfidence intervalsMetaanalysisPregnancyPatientsTotalGroupTrialsExpression and Hormonal Regulation of Monocyte Chemotactic Protein-1 in Myometrium and Leiomyomata
Sozen I, Olive D, Arici A. Expression and Hormonal Regulation of Monocyte Chemotactic Protein-1 in Myometrium and Leiomyomata. Fertility And Sterility 1998, 69: 1095-1102. PMID: 9627299, DOI: 10.1016/s0015-0282(98)00072-7.Peer-Reviewed Original ResearchConceptsMCP-1 mRNA levelsChemotactic protein-1MCP-1Leiomyoma cellsSex steroidsHigher MCP-1 levelsSteroid hormonesMCP-1 protein productionMonocyte chemotactic protein-1MCP-1 levelsMRNA levelsProtein 1Proliferative phase samplesImmunoreactive MCP-1MCP-1 expressionUniversity Medical CenterLeiomyoma cell proliferationParacrine growth factorMCP-1 mRNAGrowth stimulatory effectMessenger RNA levelsPathogenesis of leiomyomaLocal immunityGnRH analoguesProspective study
1997
Monocyte chemotactic protein-1 concentration in peritoneal fluid of women with endometriosis and its modulation of expression in mesothelial cells
Arici A, Oral E, Attar E, Tazuke S, Olive D. Monocyte chemotactic protein-1 concentration in peritoneal fluid of women with endometriosis and its modulation of expression in mesothelial cells. Fertility And Sterility 1997, 67: 1065-1072. PMID: 9176445, DOI: 10.1016/s0015-0282(97)81440-9.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1Chemotactic protein-1 levelsChemotactic protein-1Protein-1 levelsChemotactic protein-1 concentrationsProtein-1 concentrationsPeritoneal fluidMesothelial cellsPg/Severe endometriosisProtein 1Control womenSecretory phaseProliferative phaseSevere endometriosis groupPathogenesis of endometriosisPeritoneal mesothelial cellsInterleukin-1 alphaUniversity Medical CenterMessenger RNA expressionUntreated endometriosisGnRH agonistEndometriosis groupModerate endometriosisProspective study
1993
Laparoscopic removal of gonads in women with abnormal karyotypes.
Arici A, Kutteh W, Chantilis S, Johns D, Carr B. Laparoscopic removal of gonads in women with abnormal karyotypes. The Journal Of Reproductive Medicine 1993, 38: 521-5. PMID: 8410845.Peer-Reviewed Original ResearchConceptsLaparoscopic gonadectomyAverage blood lossAverage operative timeTreatment of choiceDay surgery unitUniversity Medical CenterGonadal dysgenesisBlood lossOperative timeLaparoscopic removalSurgery unitMedical CenterAbnormal karyotypePelviscopic surgeryGonadectomyPatientsAcceptable alternativeSame dayLaparoscopyAbnormal gonadsWomenDysgenesisAverage costLaparotomyComplications