2001
Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus
Sozen I, Senturk L, Arici A. Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus. Fertility And Sterility 2001, 76: 792-796. PMID: 11591415, DOI: 10.1016/s0015-0282(01)02378-0.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1Leiomyomatous uterusMacrophage countGonadotropin-releasing hormone agonistDirect paracrine effectChemotactic protein-1 productionMCP-1 levelsChemotactic protein-1MCP-1 stainingCross-sectional studyMyometrium of womenMCP-1 expressionMonocyte chemotactic protein-1 productionMCP-1 protein expressionUniversity Medical CenterProtein-1 productionGnRH agonistHormone agonistMacrophage infiltrationMedical CenterMAIN OUTCOMEImmunohistochemical analysisLeiomyoma cellsParacrine effectsGnRHExpression of aminopeptidase N in human endometrium and regulation of its activity by estrogen
Seli E, Senturk L, Bahtiyar O, Kayisli U, Arici A. Expression of aminopeptidase N in human endometrium and regulation of its activity by estrogen. Fertility And Sterility 2001, 75: 1172-1176. PMID: 11384645, DOI: 10.1016/s0015-0282(01)01779-4.Peer-Reviewed Original ResearchConceptsExpression of APNEarly proliferative phaseMenstrual cycleInterleukin-8Human endometriumProliferative phaseCultured endometrial stromal cellsEndometrial stromal cell culturesEndometrial stromal cellsUniversity Medical CenterPolymorphonuclear leukocyte chemotaxisAPN activityAminopeptidase NConcentration-dependent mannerEndometrial pathologyEndometrial stromaProspective studyStromal cell culturesEndometrial sectionsAPN antibodyMedical CenterMAIN OUTCOMESex steroidsSecretory phaseEndometrium
2000
Transforming growth factor-β3 is expressed at high levels in leiomyoma where it stimulates fibronectin expression and cell proliferation
Arici A, Sozen I. Transforming growth factor-β3 is expressed at high levels in leiomyoma where it stimulates fibronectin expression and cell proliferation. Fertility And Sterility 2000, 73: 1006-1011. PMID: 10785229, DOI: 10.1016/s0015-0282(00)00418-0.Peer-Reviewed Original ResearchConceptsTGF-beta3 mRNA levelsLeiomyoma cell proliferationCell proliferationLeiomyoma cellsFibronectin expressionMRNA levelsLeiomyoma samplesProliferative phase samplesTGF-beta3 mRNAUniversity Medical CenterFibronectin mRNA expressionExpression of fibronectinMedical CenterFibrogenic processMAIN OUTCOMESex steroidsMidsecretory phaseMyometrial cellsMyometrial samplesLeiomyomaTGF-beta3MRNA expressionGrowth-promoting effectMyometriumGrowth factor β3
1999
Interleukin-8 stimulates the adhesion of endometrial stromal cells to fibronectin
Garcia-Velasco J, Arici A. Interleukin-8 stimulates the adhesion of endometrial stromal cells to fibronectin. Fertility And Sterility 1999, 72: 336-340. PMID: 10439007, DOI: 10.1016/s0015-0282(99)00223-x.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsInterleukin-8IL-8 monoclonal antibodyStromal cellsMonoclonal antibodiesBenign gynecologic surgeryPathogenesis of endometriosisConcentration-dependent increaseConcentration-dependent mannerEndometrial implantsEndometrial diseaseGynecologic surgeryMAIN OUTCOMEAntibodiesStromal cell adhesionAdhesion assaysAcademic research laboratoriesCellsCell adhesionEndometriosisSurgeryPathogenesisDiseaseWomenProspective, randomized, crossover study to evaluate the benefit of human chorionic gonadotropin–timed versus urinary luteinizing hormone–timed intrauterine inseminations in clomiphene citrate–stimulated treatment cycles
Zreik T, Garcı́a-Velasco J, Habboosh M, Olive D, Arici A. Prospective, randomized, crossover study to evaluate the benefit of human chorionic gonadotropin–timed versus urinary luteinizing hormone–timed intrauterine inseminations in clomiphene citrate–stimulated treatment cycles. Fertility And Sterility 1999, 71: 1070-1074. PMID: 10360912, DOI: 10.1016/s0015-0282(99)00116-8.Peer-Reviewed Original ResearchConceptsPregnancy rateClomiphene citrateCrossover studyUltrasound monitoringUrinary LH levelsReproductive Medicine CenterMale factor infertilityOverall pregnancy rateHCG timingLeading follicleUnexplained infertilityLH levelsUrinary LHFactor infertilityIntrauterine inseminationMenstrual cycleInfertile couplesMAIN OUTCOMEMedicine CenterProtocol BProtocol ADay 3IUITreatment cyclesDay 10
1998
Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization–embryo transfer
Zeyneloglu H, Arici A, Olive D. Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization–embryo transfer. Fertility And Sterility 1998, 70: 492-499. PMID: 9757878, DOI: 10.1016/s0015-0282(98)00200-3.Peer-Reviewed Original ResearchConceptsIVF-ETOdds ratioPregnancy rateClinical pregnancy rateFertilization-embryo transferEffect of hydrosalpinxUniversity Medical CenterEstablishment of pregnancyClinical pregnancyImplantation rateET cyclesPregnancy lossHydrosalpinxMedical CenterMAIN OUTCOMEAbortion rateAdverse effectsReduced chanceConfidence intervalsMetaanalysisPregnancyPatientsTotalGroupTrialsBasic Fibroblast Growth Factor: Peritoneal and Follicular Fluid Levels and its Effect on Early Embryonic Development
Seli E, Zeyneloglu H, Senturk L, Bahtiyar O, Olive D, Arici A. Basic Fibroblast Growth Factor: Peritoneal and Follicular Fluid Levels and its Effect on Early Embryonic Development. Fertility And Sterility 1998, 69: 1145-1148. PMID: 9627307, DOI: 10.1016/s0015-0282(98)00074-0.Peer-Reviewed Original ResearchConceptsBasic fibroblast growth factorFibroblast growth factorPeritoneal fluidFollicular fluidBasic FGF levelsFollicular fluid levelsPresence of endometriosisFGF levelsBlastocyst formationException of ageOvulation inductionProspective studyMenstrual cycleMAIN OUTCOMEFluid levelsEndometriosisMurine preimplantation embryonic developmentGrowth factorFGF concentrationsPreimplantation embryonic developmentWomenTwo-cell murine embryosPreimplantation embryosEmbryonic developmentReproductive parametersComparison of Intrauterine Insemination with Timed Intercourse in Superovulated Cycles with Gonadotropins: A Meta-analysis
Zeyneloglu H, Arici A, Olive D, Duleba A. Comparison of Intrauterine Insemination with Timed Intercourse in Superovulated Cycles with Gonadotropins: A Meta-analysis. Fertility And Sterility 1998, 69: 486-491. PMID: 9531883, DOI: 10.1016/s0015-0282(97)00552-9.Peer-Reviewed Original ResearchConceptsPregnancy rateUnexplained infertilityProspective studyOdds ratioHusband's spermCycles of IUIEnglish-language abstractsSuperovulated cyclesTimed intercourseSuperovulation cyclesIntrauterine inseminationCommon odds ratioMAIN OUTCOMEPatient's chanceAcademic centersIUIMeta-AnalysisGonadotropinConfidence intervalsIntercoursePatientsPregnancyInfertilitySpermMEDLINE
1996
Peritoneal fluid from women with moderate or severe endometriosis inhibits sperm motility: the role of seminal fluid components**Supported by grants HD-19505 and HD-32902 (to G.H.) from the National Institutes of Health, Bethesda, Maryland.
Oral E, Arici A, Olive D, Huszar G. Peritoneal fluid from women with moderate or severe endometriosis inhibits sperm motility: the role of seminal fluid components**Supported by grants HD-19505 and HD-32902 (to G.H.) from the National Institutes of Health, Bethesda, Maryland. Fertility And Sterility 1996, 66: 787-792. PMID: 8893686, DOI: 10.1016/s0015-0282(16)58637-3.Peer-Reviewed Original ResearchConceptsPeritoneal fluidSperm motilityCell-mediated inhibitionT-testStudent's t-testRandomized studyRelated infertilitySevere endometriosisMild endometriosisFertile womenSeminal fluidMAIN OUTCOMEEndometriosisSperm fractionSperm motility inhibitionLeukocyte componentsInhibitory actionSemen analysisPhysiological salineProgressive motile spermWomenNational InstituteAndrology laboratoryOvernight incubationMotility inhibition