Featured Publications
Influence of Menthol and Green Apple E-Liquids Containing Different Nicotine Concentrations Among Youth E-Cigarette Users
Jackson A, Green B, Erythropel HC, Kong G, Cavallo DA, Eid T, Gueorguieva R, Buta E, O’Malley S, Krishnan-Sarin S. Influence of Menthol and Green Apple E-Liquids Containing Different Nicotine Concentrations Among Youth E-Cigarette Users. Experimental And Clinical Psychopharmacology 2021, 29: 355-365. PMID: 32297782, PMCID: PMC7572568, DOI: 10.1037/pha0000368.Peer-Reviewed Original Research
2022
Cannabis use among youth who vape nicotine E-cigarettes: A qualitative analysis
Davis DR, Bold KW, Kong G, Cavallo DA, Jackson A, Krishnan-Sarin S. Cannabis use among youth who vape nicotine E-cigarettes: A qualitative analysis. Drug And Alcohol Dependence 2022, 234: 109413. PMID: 35339972, PMCID: PMC9018562, DOI: 10.1016/j.drugalcdep.2022.109413.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarettesCannabis useHealth concernPsychoactive effectsStrong psychoactive effectsNicotine e-cigarettesFocus groupsPast-month e-cigarette usePatterns of cannabisCessation programmingSecondary data analysisNicotine productsStudy aimCannabisNicotineNicotine vapingGroupReportDual use
2021
Psychometric Evaluation of the Short-Form Vaping Consequences Questionnaire for Use With High School Adolescents Who Use and Do Not Use E-cigarettes
Morean ME, Davis DR, Bold KW, Kong G, Jackson A, Lee J, Kumar L, Krishnan-Sarin S. Psychometric Evaluation of the Short-Form Vaping Consequences Questionnaire for Use With High School Adolescents Who Use and Do Not Use E-cigarettes. Nicotine & Tobacco Research 2021, 24: 699-709. PMID: 34791432, PMCID: PMC8962724, DOI: 10.1093/ntr/ntab237.Peer-Reviewed Original ResearchSchool-based E-cigarette cessation programs: What do youth want?
Bold K, Kong G, Cavallo D, Davis D, Jackson A, Krishnan-Sarin S. School-based E-cigarette cessation programs: What do youth want? Addictive Behaviors 2021, 125: 107167. PMID: 34753093, PMCID: PMC8629945, DOI: 10.1016/j.addbeh.2021.107167.Peer-Reviewed Original ResearchConceptsConcentration/attentionCessation programsQualitative themesHigh school youthSchool youthIntervention developmentYouthE-cigarette usePersonal anecdotesFocus groupsCurrent e-cigarette usersRewardPerceptionDeductive approachSkillsFall 2019AbstinenceApathyInaccurate reportingThemesProgramEmbarrassmentE-cigarette usersAttentionCooling e-cigarette flavors and the association with e-cigarette use among a sample of high school students
Davis DR, Morean ME, Bold KW, Camenga D, Kong G, Jackson A, Simon P, Krishnan-Sarin S. Cooling e-cigarette flavors and the association with e-cigarette use among a sample of high school students. PLOS ONE 2021, 16: e0256844. PMID: 34469460, PMCID: PMC8409641, DOI: 10.1371/journal.pone.0256844.Peer-Reviewed Original ResearchIndividual Differences in the Associations Between Risk Factors for Alcohol Use Disorder and Alcohol Use-Related Outcomes
Haeny AM, Gueorguieva R, Jackson A, Morean ME, Krishnan-Sarin S, DeMartini KS, Pearlson GD, Anticevic A, Krystal JH, O’Malley S. Individual Differences in the Associations Between Risk Factors for Alcohol Use Disorder and Alcohol Use-Related Outcomes. Psychology Of Addictive Behaviors 2021, 35: 501-513. PMID: 34110841, PMCID: PMC9211405, DOI: 10.1037/adb0000733.Peer-Reviewed Original ResearchTargeting Peroxisome Proliferator-Activated Receptor-α (PPAR- α) to reduce paclitaxel-induced peripheral neuropathy
Caillaud M, Patel NH, White A, Wood M, Contreras KM, Toma W, Alkhlaif Y, Roberts JL, Tran TH, Jackson AB, Poklis J, Gewirtz DA, Damaj MI. Targeting Peroxisome Proliferator-Activated Receptor-α (PPAR- α) to reduce paclitaxel-induced peripheral neuropathy. Brain Behavior And Immunity 2021, 93: 172-185. PMID: 33434562, PMCID: PMC8226373, DOI: 10.1016/j.bbi.2021.01.004.Peer-Reviewed Original ResearchConceptsSensory nerve action potentialsPeripheral neuropathyCold hypersensitivityDevelopment of PNPaclitaxel-induced peripheral neuropathyPeroxisome Proliferator-Activated ReceptorsPaclitaxel-induced hypersensitivityTargeting Peroxisome ProliferatorEfficacy of fenofibrateRegulation of PPARSevere peripheral neuropathyNerve action potentialsExpression of PPARIL-6 mRNAInteresting therapeutic approachDecrease neuroinflammationCancer cell linesMechanical hypersensitivitySNAP amplitudeFenofibrate treatmentIL-1βDyslipidemia treatmentInflammatory responseTherapeutic approachesEffective treatment
2020
Trends in various e-cigarette devices used by high school adolescents from 2017-2019
Bold KW, Kong G, Morean M, Gueorguieva R, Camenga DR, Simon P, Davis DR, Jackson A, Krishnan-Sarin S. Trends in various e-cigarette devices used by high school adolescents from 2017-2019. Drug And Alcohol Dependence 2020, 219: 108497. PMID: 33421797, PMCID: PMC7861878, DOI: 10.1016/j.drugalcdep.2020.108497.Peer-Reviewed Original ResearchHigh school students’ use of JUUL pod flavors before and after JUUL implemented voluntary sales restrictions on certain flavors in 2018
Morean ME, Bold KW, Kong G, Camenga DR, Jackson A, Simon P, Davis DR, Krishnan-Sarin S. High school students’ use of JUUL pod flavors before and after JUUL implemented voluntary sales restrictions on certain flavors in 2018. PLOS ONE 2020, 15: e0243368. PMID: 33320885, PMCID: PMC7737969, DOI: 10.1371/journal.pone.0243368.Peer-Reviewed Original ResearchDifferences in JUUL Appeal Among Past and Current Youth JUUL Users
Davis DR, Krishnan-Sarin S, Bold KW, Morean ME, Jackson A, Camenga D, Kong G. Differences in JUUL Appeal Among Past and Current Youth JUUL Users. Nicotine & Tobacco Research 2020, 23: 807-814. PMID: 33247938, PMCID: PMC8095239, DOI: 10.1093/ntr/ntaa246.Peer-Reviewed Original ResearchConceptsPharmacological effectsPast usersPositive pharmacological effectsCurrent usersE-cigarettesAdverse pharmacological effectsCross-sectional surveyPeer useLogistic regressionJUUL usersPrevention effortsUse statusNicotine contentCurrent useCurrent studyConnecticut high schoolsJUUL useJUULProduct characteristicsDifferencesFirst tobacco product tried among adolescents based on race/ethnicity and socioeconomic status
Grobman B, Wu R, Jackson A, Bold KW, Morean ME, Camenga DR, Davis DR, Simon P, Krishnan-Sarin S, Kong G. First tobacco product tried among adolescents based on race/ethnicity and socioeconomic status. Addictive Behaviors 2020, 113: 106666. PMID: 33130462, PMCID: PMC8194003, DOI: 10.1016/j.addbeh.2020.106666.Peer-Reviewed Original ResearchConceptsFirst tobacco productRace/ethnicityTobacco productsSocioeconomic statusE-cigarettesLow socioeconomic statusTobacco product useLogistic regression modelsDifferent tobacco productsTobacco product usersMiddle socioeconomic statusMultinomial logistic regression modelsTobacco useGreater oddsPrevention strategiesReference groupAnalytic sampleCross-sectional survey dataProduct useCigarettesRegression modelsBluntEthnicityNon-Hispanic white studentsConnecticut high schoolsImpact of menthol on nicotine intake and preference in mice: Concentration, sex, and age differences
Bagdas D, Jackson A, Carper M, Chen RY, Akinola LS, Damaj MI. Impact of menthol on nicotine intake and preference in mice: Concentration, sex, and age differences. Neuropharmacology 2020, 179: 108274. PMID: 32827516, PMCID: PMC7572603, DOI: 10.1016/j.neuropharm.2020.108274.Peer-Reviewed Original ResearchConceptsOral nicotine consumptionEffect of mentholImpact of mentholNicotine consumptionFemale miceNicotine intakeΑ7 nicotinic acetylcholine receptorMenthol concentrationNicotine solutionHigher nicotine intakeAdolescent female miceMale C57BL/6J miceTwo-bottle choice paradigmWild-type miceNicotinic acetylcholine receptorsConcentration-dependent mannerOral nicotineC57BL/6J miceKO miceMale miceType miceMouse modelAcetylcholine receptorsHigh menthol concentrationAdult counterpartsAssociation between preference for using alcohol beverage-named e-liquids and alcohol use among high school youth
Jackson A, Wu R, Kong G, Camenga D, Morean M, Simon P, Bold K, Haeny A, Krishnan-Sarin S. Association between preference for using alcohol beverage-named e-liquids and alcohol use among high school youth. Drug And Alcohol Dependence 2020, 209: 107903. PMID: 32078976, PMCID: PMC7265357, DOI: 10.1016/j.drugalcdep.2020.107903.Peer-Reviewed Original ResearchConceptsAlcohol useE-cigarette usersPast month alcohol useE-liquid flavorsE-liquidsE-cigarettesMonth alcohol usePast monthPast-month binge drinkingPreference of alcoholAlcohol drinking statusAlcohol beveragesPast-month bingeDrinking statusMultinomial logistic regressionBinge drinkingLogistic regressionBingeAssociationAdolescent alcohol useAdolescentsMonthsLiquid flavorsConnecticut high schools
2019
Appeal of JUUL among adolescents
Kong G, Bold KW, Morean ME, Bhatti H, Camenga DR, Jackson A, Krishnan-Sarin S. Appeal of JUUL among adolescents. Drug And Alcohol Dependence 2019, 205: 107691. PMID: 31706249, PMCID: PMC7307218, DOI: 10.1016/j.drugalcdep.2019.107691.Peer-Reviewed Original ResearchHigh school students’ use of flavored e-cigarette e-liquids for appetite control and weight loss
Morean ME, Bold KW, Kong G, Camenga D, Simon P, Jackson A, Cavallo DA, Krishnan-Sarin S. High school students’ use of flavored e-cigarette e-liquids for appetite control and weight loss. Addictive Behaviors 2019, 102: 106139. PMID: 31704428, PMCID: PMC6948184, DOI: 10.1016/j.addbeh.2019.106139.Peer-Reviewed Original ResearchConceptsE-liquid useAppetite controlWeight-related reasonsWeight lossE-liquidsAdolescent e-cigarette usersE-cigarette initiationE-cigarette usersSubset of adolescentsSchool-based surveyNicotine exposureFlavored e-liquidsSmoking frequencyInclusion criteriaAnalytic sampleVapingNaïve individualsFrequent vapingCurrent usersAdolescentsSchool adolescentsHigh school adolescentsNon-missing dataSmokingControlAdolescents’ awareness of the nicotine strength and e-cigarette status of JUUL e-cigarettes
Morean ME, Bold KW, Kong G, Gueorguieva R, Camenga DR, Simon P, Jackson A, Cavallo DA, Krishnan-Sarin S. Adolescents’ awareness of the nicotine strength and e-cigarette status of JUUL e-cigarettes. Drug And Alcohol Dependence 2019, 204: 107512. PMID: 31487572, PMCID: PMC6878179, DOI: 10.1016/j.drugalcdep.2019.05.032.Peer-Reviewed Original ResearchThe β3 subunit of the nicotinic acetylcholine receptor is required for nicotine withdrawal-induced affective but not physical signs or nicotine reward in mice
Jackson AB, Toma W, Contreras KM, Alkhlaif Y, Damaj MI. The β3 subunit of the nicotinic acetylcholine receptor is required for nicotine withdrawal-induced affective but not physical signs or nicotine reward in mice. Pharmacology Biochemistry And Behavior 2019, 183: 1-5. PMID: 31145916, PMCID: PMC7197262, DOI: 10.1016/j.pbb.2019.05.003.Peer-Reviewed Original ResearchConceptsNicotine withdrawal signsWithdrawal signsNicotine rewardNicotinic acetylcholine receptorsWT miceNicotine dependenceAcetylcholine receptorsNicotine dependence behaviorsNicotine-dependent miceAffective nicotine withdrawal signsΒ3 subunitTobacco use disorderNicotine-induced CPPSimilar somatic symptomsPlace preference testNew molecular targetsAffective withdrawal signsAddictive componentSpontaneous withdrawalWithdrawal studyKO miceFemale miceHealth burdenPhysical signsUse disorders
2018
E-cigarette devices used by high-school youth
Krishnan-Sarin S, Jackson A, Morean M, Kong G, Bold KW, Camenga DR, Cavallo DA, Simon P, Wu R. E-cigarette devices used by high-school youth. Drug And Alcohol Dependence 2018, 194: 395-400. PMID: 30497057, PMCID: PMC6312472, DOI: 10.1016/j.drugalcdep.2018.10.022.Peer-Reviewed Original ResearchQuerying About the Use of Specific E-Cigarette Devices May Enhance Accurate Measurement of E-Cigarette Prevalence Rates Among High School Students
Morean ME, Camenga DR, Bold KW, Kong G, Jackson A, Simon P, Cavallo DA, Krishnan-Sarin S. Querying About the Use of Specific E-Cigarette Devices May Enhance Accurate Measurement of E-Cigarette Prevalence Rates Among High School Students. Nicotine & Tobacco Research 2018, 22: 833-837. PMID: 30395344, PMCID: PMC7171282, DOI: 10.1093/ntr/nty240.Peer-Reviewed Original ResearchNew insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice
Bagdas D, Alkhlaif Y, Jackson A, Carroll FI, Ditre JW, Damaj MI. New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice. Neuropharmacology 2018, 138: 72-79. PMID: 29860196, PMCID: PMC6054891, DOI: 10.1016/j.neuropharm.2018.05.025.Peer-Reviewed Original ResearchConceptsEffects of vareniclineNicotine withdrawal signsNicotine rewardΑ5 nAChRWithdrawal signsHigh doseKnockout miceΒ2-nAChRsNicotine withdrawal-induced hyperalgesiaAdministration of vareniclineWithdrawal-induced hyperalgesiaΑ7 knockout miceDose-related mannerNicotinic acetylcholine receptorsΑ5 knockout micePlace preference testVarenicline doseCessation treatmentNicotine withdrawalSomatic signsVareniclineΑ7 nAChRsMouse modelCPP testNicotinic subtypes