2024
IDENTIFICATION OF CRITICAL ELEMENTS FOR POINT OF CARE ULTRASOUND EDUCATOR EFFICACY: A SURVEY OF POCUS EDUCATORS
RENZETTI M, DONROE J, LIU R, CHICHRA A. IDENTIFICATION OF CRITICAL ELEMENTS FOR POINT OF CARE ULTRASOUND EDUCATOR EFFICACY: A SURVEY OF POCUS EDUCATORS. CHEST Journal 2024, 166: a3875-a3876. DOI: 10.1016/j.chest.2024.06.2338.Peer-Reviewed Original ResearchCARDIOGENIC SHOCK AND MYOCARDIAL INFARCTION IN A YOUNG PATIENT WITH THROMBOTIC THROMBOCYTOPENIC PURPURA
Mora R, Iyer D, Bozdemir E, Um H, Chichra A, Homer R, Kwan J. CARDIOGENIC SHOCK AND MYOCARDIAL INFARCTION IN A YOUNG PATIENT WITH THROMBOTIC THROMBOCYTOPENIC PURPURA. Journal Of The American College Of Cardiology 2024, 83: 4362. DOI: 10.1016/s0735-1097(24)06352-6.Peer-Reviewed Original Research
2023
Managing the Chronically Ventilated Critically Ill Population
Chichra A, Tickoo M, Honiden S. Managing the Chronically Ventilated Critically Ill Population. Journal Of Intensive Care Medicine 2023, 39: 703-714. PMID: 37787184, DOI: 10.1177/08850666231203601.Peer-Reviewed Original ResearchCritical illnessMechanical ventilationAcute critical illnessCritically Ill PopulationIntensive care therapyPopulation of patientsCare therapyAcute periodHigh morbidityIntensive carePalliative careDisease burdenIll populationNeuroendocrine disordersPsychiatric effectsHealthcare costsPsychiatric issuesNutritional deficienciesChances of survivalPatientsWeaning strategiesSignificant increaseIllnessCareVentilationA Tool to Assess Competence in Critical Care Ultrasound Based on Entrustable Professional Activities
Israel H, Slade M, Gielissen K, Liu R, Pisani M, Chichra A. A Tool to Assess Competence in Critical Care Ultrasound Based on Entrustable Professional Activities. ATS Scholar 2023, 4: 61-75. PMID: 37089679, PMCID: PMC10117444, DOI: 10.34197/ats-scholar.2022-0063oc.Peer-Reviewed Original ResearchCritical care ultrasoundCritical care fellowsCare ultrasoundStudy periodAssessment toolEntrustable professional activitiesCritical Care SocietyResponse process validityAssessment of validitySingle institutionExpert consensusNominal group techniqueEntrustment scoresSufficient validity evidenceRegression analysisScoresContent validityClinical workflowProcess validityRegression modelsValidity evidenceUltrasoundHigh agreementCore Entrustable Professional ActivitiesICUA Tool to Assess Competence in Critical Care Ultrasound Based on Entrustable Professional Activities.
Israel HP, Slade M, Gielissen K, Liu RB, Pisani MA, Chichra A. A Tool to Assess Competence in Critical Care Ultrasound Based on Entrustable Professional Activities. ATS Scholar. 2023 Jan:ats-scholar.Peer-Reviewed Original Research
2022
The Use of Diaphragm Ultrasonography to Predict Outcomes in Patients With Acute COPD Exacerbation
Ahmad R, Chichra A. The Use of Diaphragm Ultrasonography to Predict Outcomes in Patients With Acute COPD Exacerbation. 2022, a1081-a1081. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1081.Peer-Reviewed Original ResearchCombined Use of ECMO, Prone Positioning, and APRV in the Management of Severe COVID-19 Patients
Ong S, Tantawy H, Assi R, Chichra A, Treggiari M. Combined Use of ECMO, Prone Positioning, and APRV in the Management of Severe COVID-19 Patients. Clinical Medicine Insights Circulatory Respiratory And Pulmonary Medicine 2022, 16: 11795484221134451. PMID: 36419562, PMCID: PMC9677293, DOI: 10.1177/11795484221134451.Peer-Reviewed Original ResearchAcute respiratory distress syndromeExtracorporeal membrane oxygenationCOVID-19-associated acute respiratory distress syndromeProne positioningVV-ECMODeep tissue injuryTissue injurySevere COVID-19-associated acute respiratory distress syndromeVeno-venous (VV) ECMOCOVID-19 acute respiratory distress syndromeSevere COVID-19 patientsTreatment-related complicationsConsecutive adult patientsRespiratory distress syndromeCOVID-19 populationCOVID-19 patientsHospital mortalityVasopressor requirementECMO supportAdult patientsCohort studyHemodynamic profilePhysiologic improvementDistress syndromeMembrane oxygenationA commentary on: Extended Lung Ultrasound to Differentiate Between Pneumonia and Atelectasis in Critically Ill Patients: A Diagnostic Accuracy Study.
Chichra A. A commentary on: Extended Lung Ultrasound to Differentiate Between Pneumonia and Atelectasis in Critically Ill Patients: A Diagnostic Accuracy Study. PracticeUpdate website. Available at: https://www.practiceupdate.com/content/extended-lung-ultrasound-to-differentiate-between-pneumonia-and-atelectasis-in-critically-ill-patients/136106/65/20/1. Accessed June 09, 2022Commentaries, Editorials and Letters
2021
1143: HYPOXIC RESPIRATORY FAILURE CAUSED BY OSIMERTINIB-INDUCED ACUTE FIBRINOUS AND ORGANIZING PNEUMONIA
Hunter N, Matsumoto N, Carpio A, Chichra A. 1143: HYPOXIC RESPIRATORY FAILURE CAUSED BY OSIMERTINIB-INDUCED ACUTE FIBRINOUS AND ORGANIZING PNEUMONIA. Critical Care Medicine 2021, 50: 570-570. DOI: 10.1097/01.ccm.0000810896.08898.49.Peer-Reviewed Original Research284: METHYLPREDNISOLONE VERSUS USUAL CARE FOR COVID-19-ASSOCIATED ACUTE RESPIRATORY DISTRESS SYNDROME
Owusu K, Ammar M, Ammar A, Chess A, Siner J, Fajardo E, Chichra A. 284: METHYLPREDNISOLONE VERSUS USUAL CARE FOR COVID-19-ASSOCIATED ACUTE RESPIRATORY DISTRESS SYNDROME. Critical Care Medicine 2021, 50: 127-127. DOI: 10.1097/01.ccm.0000807460.83646.b2.Peer-Reviewed Original ResearchMalignant hyperthermia in severe COVID-19: 2 case reports
Ehteshami-Afshar S, Nikooie R, Reddy P, Chichra A, Siegel M. Malignant hyperthermia in severe COVID-19: 2 case reports. Emergency And Critical Care Medicine 2021, 1: 45-48. PMID: 38630110, PMCID: PMC8447731, DOI: 10.1097/ec9.0000000000000013.Peer-Reviewed Original ResearchCytokine profiles in severe SARS-CoV-2 infection requiring extracorporeal membrane oxygenation support
Kaman K, Azmy V, Chichra A, Britto-Leon C, Price C. Cytokine profiles in severe SARS-CoV-2 infection requiring extracorporeal membrane oxygenation support. Respiratory Medicine Case Reports 2021, 33: 101376. PMID: 33680800, PMCID: PMC7925237, DOI: 10.1016/j.rmcr.2021.101376.Peer-Reviewed Original ResearchExtracorporeal membrane oxygenation supportMembrane oxygenation supportVV-ECMOOxygenation supportCytokine stormVeno-venous extracorporeal membrane oxygenation supportSevere SARS-CoV-2 infectionSARS-CoV-2 infectionVV-ECMO supportRefractory respiratory failureProspective cohort studyCohort of patientsInterleukin-2 receptorCytokine elevationHyperinflammatory stateECMO supportRespiratory failureCohort studyCytokine profileClinical courseInterleukin-10COVID19 patientsUnderlying pathophysiologyInterleukin-6Inflammatory responseMalignant hyperthermia in severe COVID-19: 2 case reports
Ehteshami-Afshar S, Nikooie R, Reddy P, Chichra A, Siegel MD. Malignant hyperthermia in severe COVID-19: 2 case reports. Emergency and Critical Care Medicine. 2021 Sep 15;1(1):45–8. doi: 10.1097/EC9.0000000000000013. PMCID: PMC8447731.Peer-Reviewed Case Reports and Technical NotesA commentary on: Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry.
Chichra A. A commentary on: Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry. PracticeUpdate website. Available at: https://www.practiceupdate.com/content/evolving-outcomes-observed-in-patients-with-covid-19-on-extracorporeal-membrane-oxygenation/124733/65/20/1. Accessed October 26, 2021Commentaries, Editorials and Letters
2020
CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH COVID-19 WITH RESPIRATORY FAILURE REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATION
Fouad J, Singh I, Khosla A, Szabo C, Tantawy H, Razo-Vazquez A, Geirsson A, Bonde P, Fajardo E, Joseph P, Siner J, Chichra A. CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH COVID-19 WITH RESPIRATORY FAILURE REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATION. CHEST Journal 2020, 158: a703-a704. PMCID: PMC7548617, DOI: 10.1016/j.chest.2020.08.660.Peer-Reviewed Original ResearchChichra A. High-Flow Oxygen With Capping or Suctioning for Tracheostomy Decannulation.
Chichra A. High-Flow Oxygen With Capping or Suctioning for Tracheostomy Decannulation. PracticeUpdate website. Available at: https://www.practiceupdate.com/content/high-flow-oxygen-with-capping-or-suctioning-for-tracheostomy-decannulation/107373/65/20/1. Accessed October 22, 2020Commentaries, Editorials and LettersChichra A. Emergence of Alveolar Consolidations in Serial Lung Ultrasound and Diagnosis of Ventilator-Associated Pneumonia.
Chichra A. Emergence of Alveolar Consolidations in Serial Lung Ultrasound and Diagnosis of Ventilator-Associated Pneumonia. PracticeUpdate website. Available at: https://www.practiceupdate.com/content/emergence-of-alveolar-consolidations-in-serial-lung-ultrasound-and-diagnosis-of-ventilator-associated-pneumonia/94564/65/20/1. Accessed January 15, 2020Commentaries, Editorials and LettersHijaking the SARS-CoV-2 Cytokinopathy: Janus Kinase Inhibitors for Moderate to Severe COVID-19
Won, C., Damsky, W., Singh, I., Joseph, P., Chichra, A., Oakland, H., Lu, J., Vallabhajosyula, P., Bardia, A., Szabo, C. and Wang, A., 2020. Hijaking the SARS-CoV-2 Cytokinopathy: Janus Kinase Inhibitors for Moderate to Severe COVID-19.Peer-Reviewed Original Research
2019
Impact of Obesity on Ventricular Assist Device Outcomes
Jaiswal A, Truby LK, Chichra A, Jain R, Myers L, Patel N, Topkara VK. Impact of Obesity on Ventricular Assist Device Outcomes. Journal Of Cardiac Failure 2019, 26: 287-297. PMID: 31618696, PMCID: PMC7141964, DOI: 10.1016/j.cardfail.2019.10.001.Peer-Reviewed Original ResearchConceptsBody mass indexImpact of obesityObese patientsVAD implantationSignificant weight lossVentricular assist deviceClinical outcomesWeight lossHeart transplantationBMI groupsCardiac arrhythmiasMechanically Assisted Circulatory Support registryPatients warrants further investigationVentricular assist device outcomesWorld Health Organization classificationAdvanced heart failureWarrants further investigationBleeding riskCardiac transplantationInteragency RegistryRelative contraindicationHeart failureHospital readmissionVAD therapyMass index
2018
Neurohormonal modulation as therapeutic avenue for right ventricular dysfunction in pulmonary artery hypertension: till the dawn, waiting.
Emanuel R, Chichra A, Patel N, Le Jemtel TH, Jaiswal A. Neurohormonal modulation as therapeutic avenue for right ventricular dysfunction in pulmonary artery hypertension: till the dawn, waiting. Annals Of Translational Medicine 2018, 6: 301. PMID: 30211189, PMCID: PMC6123204, DOI: 10.21037/atm.2018.06.04.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPulmonary arterial hypertensionRight ventricular dysfunctionRV dysfunctionVentricular dysfunctionManagement of PAHAldosterone system modulationNeuro-hormonal activationPulmonary artery hypertensionBeta-adrenergic blockadeNon-pharmacological modalitiesCurrent clinical experienceArtery hypertensionArterial hypertensionNeurohormonal activationPAH patientsSystemic hypotensionAdrenergic blockadePathophysiological backgroundSignificant morbidityNeurohormonal modulationClinical studiesClinical experienceSystem modulationDysfunctionTherapeutic avenues