Acute Phencyclidine Alters Neural Oscillations Evoked by Tones in the Auditory Cortex of Rats
Martin A, OʼDonnell BF, Millward JB, Vohs JL, Leishman E, Bolbecker AR, Rass O, Morzorati SL. Acute Phencyclidine Alters Neural Oscillations Evoked by Tones in the Auditory Cortex of Rats. Neuropsychobiology 2017, 75: 53-62. PMID: 29065422, PMCID: PMC5752597, DOI: 10.1159/000480511.Peer-Reviewed Original ResearchConceptsAcute PCPSubchronic administrationAuditory cortexN-methyl-D-aspartate (NMDA) receptor systemGamma range frequenciesPathophysiology of schizophreniaGamma range activityEffects of PCPN70 componentsAcute administrationDrug cessationEvent-related potentialsNMDAR hypofunctionNMDAR antagonistsTranslational biomarkersNMDAR functionBACKGROUND/EEG spectral powerOnset responsePCP doseMean powerNeuropsychiatric disordersReceptor systemNeural powerSimilar deficits