2003
Contribution of mitochondria to cardiac muscle water/macromolecule proton magnetization transfer
Ward K, Schussheim A, Balaban R. Contribution of mitochondria to cardiac muscle water/macromolecule proton magnetization transfer. Magnetic Resonance In Medicine 2003, 50: 1312-1316. PMID: 14648581, DOI: 10.1002/mrm.10625.Peer-Reviewed Original Research
1998
Regulation of Cardiac Myocyte Contractile Function by Inducible Nitric Oxide Synthase (iNOS): Mechanisms of Contractile Depression by Nitric Oxide
Joe E, Schussheim A, Longrois D, Mäki T, Kelly R, Smith T, Balligand J. Regulation of Cardiac Myocyte Contractile Function by Inducible Nitric Oxide Synthase (iNOS): Mechanisms of Contractile Depression by Nitric Oxide. Journal Of Molecular And Cellular Cardiology 1998, 30: 303-315. PMID: 9515007, DOI: 10.1006/jmcc.1997.0593.Peer-Reviewed Original ResearchMeSH Keywords1-Methyl-3-isobutylxanthineAcetylcysteineAdenylyl CyclasesAdrenergic beta-AgonistsAnimalsCulture Media, ConditionedCyclic AMPCyclic GMPEnzyme InductionGTP-Binding ProteinsIn Vitro TechniquesIsoproterenolLipopolysaccharidesMacrophages, AlveolarMyocardial ContractionNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type IIPhosphodiesterase InhibitorsRatsRats, Sprague-DawleyConceptsInducible nitric oxide synthaseInduction of iNOSBeta-adrenergic stimulationMacrophage-conditioned mediumNM IsoCardiac myocytesContractile responseContractile functionBeta-adrenergic receptor densityNitric oxideMyocyte contractile functionSystemic immune stimulationCardiac contractile functionNitric oxide synthaseCardiac myocyte contractile functionRat lung macrophagesAdenylyl cyclase activityCultured ventricular myocytesContractile depressionNOS inhibitionAdrenergic responsivenessInflammatory cytokinesElevation of cAMPCardiac functionNOS inhibitor
1995
Altered Na+-H+-exchange activity in the spontaneously hypertensive perfused rat heart
Schussheim A, Radda G. Altered Na+-H+-exchange activity in the spontaneously hypertensive perfused rat heart. Journal Of Molecular And Cellular Cardiology 1995, 27: 1475-1481. PMID: 8523411, DOI: 10.1016/s0022-2828(95)90128-0.Peer-Reviewed Original ResearchConceptsRat heartWistar-Kyoto controlsHypertensive rat heartsSHR groupSHR heartsFunctional recoveryDeveloped pressureHypercapnic acidosisControl groupPerfusion techniqueAcidosisSignificant differencesHeartExchange activitySpecific inhibitorMagnetic resonance spectroscopyGroupEarly periodHypertensionMajor role