2024
Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Varthi A, Rubio D, Grauer J. Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024 PMID: 39491749, DOI: 10.1016/j.spinee.2024.10.011.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsAdverse eventsPostoperative complicationsT2DM patientsCurrent Procedural TerminologyElixhauser Comorbidity IndexED visitsLumbar fusionHospital readmissionEmergency departmentOdds of postoperative complicationsNinety-day postoperative complicationsImpact of semaglutideOdds of hospital readmissionMonths of surgeryRetrospective cohort studyPostoperative adverse eventsMinor adverse eventsType II diabetes mellitusRisk of type I errorDiagnosis of T2DMII diabetes mellitusYears of age
2022
Underweight patients are the highest risk body mass index group for perioperative adverse events following stand-alone anterior lumbar interbody fusion
Ottesen TD, Galivanche AR, Greene JD, Malpani R, Varthi AG, Grauer JN. Underweight patients are the highest risk body mass index group for perioperative adverse events following stand-alone anterior lumbar interbody fusion. The Spine Journal 2022, 22: 1139-1148. PMID: 35231643, DOI: 10.1016/j.spinee.2022.02.012.Peer-Reviewed Original ResearchConceptsBody mass indexNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseAnterior lumbar interbody fusionObese class 1Improvement Program databaseClass 2 patientsAdverse eventsUnderweight patientsBMI categoriesAdverse outcomesBMI spectrumInterbody fusionProgram databaseTwo-level anterior lumbar interbody fusionSurgeons National Surgical Quality Improvement Program databaseMultivariate analysisThirty-day adverse eventsWorld Health Organization categoriesBody mass index groupsPostoperative adverse eventsRetrospective cohort studyPerioperative adverse eventsNormal-weight subjectsPost-operative infection
2016
Perioperative Outcomes After Cervical Laminoplasty Versus Posterior Decompression and Fusion
Varthi AG, Basques BA, Bohl DD, Golinvaux NS, Grauer JN. Perioperative Outcomes After Cervical Laminoplasty Versus Posterior Decompression and Fusion. Clinical Spine Surgery A Spine Publication 2016, 29: e226-e232. PMID: 25310393, DOI: 10.1097/bsd.0000000000000183.Peer-Reviewed Original ResearchConceptsMultilevel cervical pathologyBaseline patient characteristicsCervical laminoplastyShort-term outcomesPosterior decompressionLaminoplasty patientsFusion patientsCervical decompressionAdverse eventsPatient characteristicsCervical pathologySurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databasePropensity-adjusted multivariate analysisQuality Improvement Program databaseWorse short-term outcomesCharlson Comorbidity IndexPosterior cervical decompressionRetrospective cohort studyImprovement Program databaseLength of stayBivariate logistic regressionAnesthesiologists (ASA) scoreComorbidity indexPerioperative outcomes
2015
Overall Similar Infection Rates Reported in the Physician-reported Scoliosis Research Society Database and the Chart-abstracted American College of Surgeons National Surgical Quality Improvement Program Database
Webb ML, Lukasiewicz AM, Samuel AM, Bohl DD, Basques BA, Varthi AG, Grauer JN. Overall Similar Infection Rates Reported in the Physician-reported Scoliosis Research Society Database and the Chart-abstracted American College of Surgeons National Surgical Quality Improvement Program Database. Spine 2015, 40: 1431-1435. PMID: 26110664, DOI: 10.1097/brs.0000000000001033.Peer-Reviewed Original ResearchConceptsACS-NSQIP databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseImprovement Program databaseInfection rateSRS databasePostoperative infectionProgram databaseAmerican CollegeScoliosis Research Society MorbidityAcute postoperative infectionSurgeon-reported dataPostoperative infection rateRetrospective cohort studyNinth Revision codesSimilar infection ratesDegenerative spondylolithesisCohort studyScheuermann's kyphosisSurgical databaseRevision codesSurgical correctionBACKGROUND DATASurgical cases
2014
Complication Rates Following Elective Lumbar Fusion in Patients With Diabetes
Golinvaux NS, Varthi AG, Bohl DD, Basques BA, Grauer JN. Complication Rates Following Elective Lumbar Fusion in Patients With Diabetes. Spine 2014, 39: 1809-1816. PMID: 25010098, DOI: 10.1097/brs.0000000000000506.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChi-Square DistributionDatabases, FactualDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Elective Surgical ProceduresFemaleHumansHypoglycemic AgentsInsulinLength of StayLogistic ModelsLumbar VertebraeMaleMiddle AgedMultivariate AnalysisOdds RatioPatient ReadmissionPostoperative ComplicationsRetrospective StudiesRisk FactorsSpinal FusionTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsInsulin-dependent diabetes mellitusLumbar fusion surgeryDiabetes mellitusPostoperative complicationsFusion surgeryLumbar fusionSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseElective lumbar fusion surgeryQuality Improvement Program databaseEffects of NIDDMVentilator-assisted respirationWound-related infectionsAdverse postoperative outcomesRetrospective cohort studyImprovement Program databaseUrinary tract infectionDependent diabetes mellitusElective lumbar fusionPreoperative risk stratificationRisk of deathCommon chronic diseasesLength of stayCounseling of patientsUnplanned intubationFactors Predictive of Increased Surgical Drain Output After Anterior Cervical Discectomy and Fusion
Basques BA, Bohl DD, Golinvaux NS, Yacob A, Varthi AG, Grauer JN. Factors Predictive of Increased Surgical Drain Output After Anterior Cervical Discectomy and Fusion. Spine 2014, 39: 728-735. PMID: 24480948, PMCID: PMC3991728, DOI: 10.1097/brs.0000000000000237.Peer-Reviewed Original ResearchConceptsTotal drain outputDrain outputSurgical drain placementSurgical drain outputNeck hematomaDrain placementSurgical drainsRetrospective cohort studyAnterior cervical discectomyHistory of smokingRisk of complicationsPostoperative neck hematomaAge 50 yearsMultivariate logistic regressionSingle academic institutionAverage drain outputElective ACDFCervical discectomyCohort studyConsecutive patientsDrain useIndependent predictorsFactors PredictiveMedical recordsACDF