Prenatal Opioid and Alcohol Exposures: Association with Altered Placental Serotonin Transporter Structure and/or Expression
Darbinian N, Merabova N, Tatevosian G, Adele S, Darbinyan A, Morrison M, DeVane C, Ramamoorthy S, Goetzl L, Selzer M. Prenatal Opioid and Alcohol Exposures: Association with Altered Placental Serotonin Transporter Structure and/or Expression. International Journal Of Molecular Sciences 2024, 25: 11570. PMID: 39519122, PMCID: PMC11546934, DOI: 10.3390/ijms252111570.Peer-Reviewed Original ResearchSERT expressionGestational age-matched controlsBrain serotonergic neurotransmissionElective pregnancy terminationTrimester human placentaPlacental membrane vesiclesDrugs of abuseAge-matched controlsOpioid-exposedPrenatal opioidsOpioid groupSERT levelsSerotonergic neurotransmissionFetal exposureMaternal placentaPregnancy terminationPregnant womenAlcohol exposureNeurodevelopmental implicationsQuantitative Western blottingHuman placentaOpioidNeurodevelopmental problemsPrenatal substance exposurePlacenta