2024
The association between prolonged SARS-CoV-2 symptoms and work outcomes
Venkatesh A, Yu H, Malicki C, Gottlieb M, Elmore J, Hill M, Idris A, Montoy J, O’Laughlin K, Rising K, Stephens K, Spatz E, Weinstein R, Group F. The association between prolonged SARS-CoV-2 symptoms and work outcomes. PLOS ONE 2024, 19: e0300947. PMID: 39074096, PMCID: PMC11285965, DOI: 10.1371/journal.pone.0300947.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 symptomsReturn to workAssociated with increased oddsAnalyzed self-reported dataNational cohort studySelf-reported dataLong COVIDCOVID-19 pandemicLost work timePublic health emergencyWork absenteeismMissed workdaysElectronic surveyEmployment statusSARS-CoV-2 infectionWell-being impactsOdds ratioWork lossCohort studyNumerous healthImpact of long COVIDCOVID-19Risk factorsThree-monthsHealth emergency
2023
Race and Ethnicity and Emergency Department Discharge Against Medical Advice
Tsai J, Janke A, Krumholz H, Khidir H, Venkatesh A. Race and Ethnicity and Emergency Department Discharge Against Medical Advice. JAMA Network Open 2023, 6: e2345437. PMID: 38015503, PMCID: PMC10685883, DOI: 10.1001/jamanetworkopen.2023.45437.Peer-Reviewed Original ResearchConceptsWhite patientsHispanic patientsEmergency departmentCross-sectional studyED visitsBlack patientsDAMA rateMedical adviceMAIN OUTCOMEEthnic disparitiesNationwide Emergency Department SampleNational cross-sectional studyHospital ED visitsEmergency department dischargeHospital-level variationEmergency Department SampleMetropolitan teaching hospitalHealth care resourcesMedian ageGreater morbidityHospital variationUnadjusted analysesTeaching hospitalAdditional adjustmentLower oddsPrevalence of Symptoms ≤12 Months After Acute Illness, by COVID-19 Testing Status Among Adults — United States, December 2020–March 2023
Montoy J, Ford J, Yu H, Gottlieb M, Morse D, Santangelo M, O’Laughlin K, Schaeffer K, Logan P, Rising K, Hill M, Wisk L, Salah W, Idris A, Huebinger R, Spatz E, Rodriguez R, Klabbers R, Gatling K, Wang R, Elmore J, McDonald S, Stephens K, Weinstein R, Venkatesh A, Saydah S, Group I, Group I, Ahmed Z, Choi M, Derden A, Gottlieb M, Guzman D, Hassaballa M, Jerger R, Kaadan M, Koo K, Yang G, Dorney J, Kinsman J, Li S, Lin Z, Mannan I, Pierce S, Puente X, Ulrich A, Yang Z, Yu H, Adams K, Anderson J, Chang G, Gentile N, Geyer R, Maat Z, Malone K, Nichol G, Park J, Ruiz L, Schiffgens M, Stober T, Willis M, Zhang Z, Amadio G, Charlton A, Cheng D, Grau D, Hannikainen P, Kean E, Kelly M, Miao J, Renzi N, Shughart H, Shughart L, Shutty C, Watts P, Kane A, Nikonowicz P, Sapp S, Gallegos D, Martin R, Chandler C, Eguchi M, L’Hommedieu M, Moreno R, Roldan K, Arreguin M, Chan V, Chavez C, Kemball R, Wong A, Briggs-Hagen M, Hall A, Plumb I. Prevalence of Symptoms ≤12 Months After Acute Illness, by COVID-19 Testing Status Among Adults — United States, December 2020–March 2023. MMWR Morbidity And Mortality Weekly Report 2023, 72: 859-865. PMID: 37561663, PMCID: PMC10415002, DOI: 10.15585/mmwr.mm7232a2.Peer-Reviewed Original ResearchConceptsCOVID-like illnessSARS-CoV-2 test resultsPost-COVID conditionsNegative SARS-CoV-2 test resultsPositive SARS-CoV-2 test resultProspective multicenter cohort studySARS-CoV-2 infectionMulticenter cohort studyPrevalence of symptomsTime of enrollmentCOVID-19 testing statusHealth care providersSARS-CoV-2Self-reported symptomsCohort studyPersistent symptomsAcute illnessAntigen testPolymerase chain reactionClinical signsSymptom progressionCare providersDrug AdministrationTesting statusSymptomsEmergency medicine physician workforce attrition differences by age and gender
Gettel C, Courtney D, Agrawal P, Madsen T, Rothenberg C, Mills A, Lall M, Keim S, Kraus C, Ranney M, Venkatesh A. Emergency medicine physician workforce attrition differences by age and gender. Academic Emergency Medicine 2023, 30: 1092-1100. PMID: 37313983, PMCID: PMC10973949, DOI: 10.1111/acem.14764.Peer-Reviewed Original ResearchConceptsFemale emergency physiciansEmergency physiciansMedian ageMultivariate logistic regression modelMale emergency physiciansResidency graduationRepeated cross-sectional analysisCharacteristics of physiciansWorkforce attritionCross-sectional analysisLogistic regression modelsStudy time frameDate of birthPrimary outcomeFemale genderMale physiciansClinical practiceFemale physiciansClinical servicesPhysiciansEmergency medicineAgeNumber of yearsRecent dataWorkforce concernsClinical Performance Measures for Emergency Department Care for Adults With Intracranial Hemorrhage
Zachrison K, Goldstein J, Jauch E, Radecki R, Madsen T, Adeoye O, Oostema J, Feeser V, Ganti L, Lo B, Meurer W, Corral M, Rothenberg C, Chaturvedi A, Goyal P, Venkatesh A. Clinical Performance Measures for Emergency Department Care for Adults With Intracranial Hemorrhage. Annals Of Emergency Medicine 2023, 82: 258-269. PMID: 37074253, DOI: 10.1016/j.annemergmed.2023.03.015.Peer-Reviewed Original ResearchConceptsIntracranial hemorrhageAcute neurologic emergenciesEmergency department careNontraumatic intracranial hemorrhageCare of patientsClinical performance measuresCommunity EDNeurologic emergencySyndromic approachEmergency departmentEvidence-based targetsHyperacute phaseWarrants further developmentWorkgroup of expertsQuality improvement resourcesCare processesReview of dataQuality improvementHemorrhageInternal quality improvementCareNational sampleBroad implementationEDImprovement resourcesClinical criteria to exclude acute vascular pathology on CT angiogram in patients with dizziness
Tu L, Malhotra A, Venkatesh A, Taylor R, Sheth K, Yaesoubi R, Forman H, Sureshanand S, Navaratnam D. Clinical criteria to exclude acute vascular pathology on CT angiogram in patients with dizziness. PLOS ONE 2023, 18: e0280752. PMID: 36893103, PMCID: PMC9997874, DOI: 10.1371/journal.pone.0280752.Peer-Reviewed Original ResearchConceptsAcute vascular pathologyEmergency departmentVascular pathologyNegative predictive valueDizzy patientsStroke codeCTA headPredictive valueAdult ED encountersTransient ischemic attackHalf of patientsLong-term smokersLarge vessel occlusionCoronary artery diseasePast medical historySeparate validation cohortCross-sectional analysisIschemic attackAnalysis cohortArterial dissectionArtery diseaseClinical factorsED encountersMedication useChief complaint
2022
Three-Month Symptom Profiles Among Symptomatic Adults With Positive and Negative Severe Acute Respiratory Syndrome Coronavirus 2 Tests: A Prospective Cohort Study From the INSPIRE Group
Spatz E, Gottlieb M, Wisk L, Anderson J, Chang A, Gentile N, Hill M, Huebinger R, Idris A, Kinsman J, Koo K, Li S, McDonald S, Plumb I, Rodriguez R, Saydah S, Slovis B, Stephens K, Unger E, Wang R, Yu H, Hota B, Elmore J, Weinstein R, Venkatesh A. Three-Month Symptom Profiles Among Symptomatic Adults With Positive and Negative Severe Acute Respiratory Syndrome Coronavirus 2 Tests: A Prospective Cohort Study From the INSPIRE Group. Clinical Infectious Diseases 2022, 76: 1559-1566. PMID: 36573005, DOI: 10.1093/cid/ciac966.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 symptomsSARS-CoV-2 infectionPost-infectious syndromesProspective cohort studyCohort studyCOVID groupAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSARS-CoV-2 test resultsSyndrome coronavirus 2 infectionEar/nose/throatSevere acute respiratory syndrome coronavirus 2 testsCoronavirus 2 infectionLong-term symptomsNose/throatLong COVIDSymptomatic adultsMean ageActive symptomsSymptom profilesDrug AdministrationSociodemographic characteristicsSymptomsInfectionMonthsAssociation of Initial SARS-CoV-2 Test Positivity With Patient-Reported Well-being 3 Months After a Symptomatic Illness
Wisk L, Gottlieb M, Spatz E, Yu H, Wang R, Slovis B, Saydah S, Plumb I, O’Laughlin K, Montoy J, McDonald S, Lin Z, Lin J, Koo K, Idris A, Huebinger R, Hill M, Gentile N, Chang A, Anderson J, Hota B, Venkatesh A, Weinstein R, Elmore J, Nichol G, Santangelo M, Ulrich A, Li S, Kinsman J, Krumholz H, Dorney J, Stephens K, Black K, Morse D, Morse S, Fernandes A, Sharma A, Stober T, Geyer R, Lyon V, Adams K, Willis M, Ruiz L, Park J, Malone K, Shughart H, Schaeffer K, Shughart L, Arab A, Grau D, Patel A, Watts P, Kelly M, Hunt A, Hannikainen P, Chalfin M, Cheng D, Miao J, Shutty C, Chavez S, Kane A, Marella P, Gallegos G, Martin K, L'Hommedieu M, Chandler C, Diaz Roldan K, Villegas N, Moreno R, Eguchi M, Rodriguez R, Kemball R, Chan V, Chavez C, Wong A, Hall A, Briggs-Hagen M. Association of Initial SARS-CoV-2 Test Positivity With Patient-Reported Well-being 3 Months After a Symptomatic Illness. JAMA Network Open 2022, 5: e2244486. PMID: 36454572, PMCID: PMC9716377, DOI: 10.1001/jamanetworkopen.2022.44486.Peer-Reviewed Original ResearchConceptsCOVID-19 positive groupCOVID-19-negative groupSARS-CoV-2 infectionCOVID-19 testCOVID-19 resultsSymptomatic illnessSymptomatic SARS-CoV-2 infectionNegative COVID-19 resultsSARS-CoV-2 statusSARS-CoV-2 test positivityPositive COVID-19 testSARS-CoV-2 testNegative COVID-19 testLongitudinal registry studyOutcomes Measurement Information SystemPatient-reported outcomesHealth care usePositive COVID-19 resultMultivariable regression analysisMeasurement Information SystemCOVID-19 testingNegative test resultsCohort studyRegistry studyPROMIS scoresMapping emergency department asthma visits to identify poor-quality housing in New Haven, CT, USA: a retrospective cohort study
Samuels EA, Taylor RA, Pendyal A, Shojaee A, Mainardi AS, Lemire ER, Venkatesh AK, Bernstein SL, Haber AL. Mapping emergency department asthma visits to identify poor-quality housing in New Haven, CT, USA: a retrospective cohort study. The Lancet Public Health 2022, 7: e694-e704. PMID: 35907420, PMCID: PMC9387147, DOI: 10.1016/s2468-2667(22)00143-8.Peer-Reviewed Original ResearchConceptsEmergency department useRetrospective cohort studyEmergency departmentDepartment useCohort studyAsthma-related emergency departmentPoor housing conditionsAsthma incidence ratesEmergency department asthmaTertiary emergency departmentAsthma-related morbidityEmergency department visitsPoor quality housingHealth Sciences CenterHousing conditionsHousing inspectionDepartment visitsPatient ageRegression modelsAsthma incidenceUnique patientsIncidence rateAsthmaPatient addressesElevated incidenceDevelopment of a Novel Emergency Department Quality Measure to Reduce Very Low-Risk Syncope Hospitalizations
Probst MA, Janke AT, Haimovich AD, Venkatesh AK, Lin MP, Kocher KE, Nemnom MJ, Thiruganasambandamoorthy V. Development of a Novel Emergency Department Quality Measure to Reduce Very Low-Risk Syncope Hospitalizations. Annals Of Emergency Medicine 2022, 79: 509-517. PMID: 35487840, PMCID: PMC9117517, DOI: 10.1016/j.annemergmed.2022.03.008.Peer-Reviewed Original ResearchConceptsNationwide Emergency Department SampleLow-risk cohortHospitalization ratesUnexplained syncopeHeart diseaseED patient dataEmergency department evaluationHospital-level factorsSerious adverse eventsAdult ED patientsEmergency Department SampleSyncope hospitalizationsOutpatient managementAdult patientsAdverse eventsProspective cohortDepartment evaluationED patientsRelated hospitalizationsRisk stratificationED volumeSyncopePatientsHospitalizationMedian rateStudy protocol for the Innovative Support for Patients with SARS-COV-2 Infections Registry (INSPIRE): A longitudinal study of the medium and long-term sequelae of SARS-CoV-2 infection
O’Laughlin K, Thompson M, Hota B, Gottlieb M, Plumb ID, Chang AM, Wisk LE, Hall AJ, Wang RC, Spatz ES, Stephens KA, Huebinger RM, McDonald SA, Venkatesh A, Gentile N, Slovis BH, Hill M, Saydah S, Idris AH, Rodriguez R, Krumholz HM, Elmore JG, Weinstein RA, Nichol G, . Study protocol for the Innovative Support for Patients with SARS-COV-2 Infections Registry (INSPIRE): A longitudinal study of the medium and long-term sequelae of SARS-CoV-2 infection. PLOS ONE 2022, 17: e0264260. PMID: 35239680, PMCID: PMC8893622, DOI: 10.1371/journal.pone.0264260.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionLong-term sequelaePatient-reported outcomesRelative riskAcute SARS-CoV-2 infectionSARS-CoV-2 negative participantsHealth system encountersPredictors of sequelaeHealth recordsInstitutional review board approvalLongitudinal studyDigital health recordsReview board approvalSARS-CoV-2Secure online platformClinical outcomesStudy protocolNegative participantsViral testsSimilar symptomatologyNew diagnosisBoard approvalSequelaeSelf-administered surveyInfection
2021
Feasibility and acceptability of electronic administration of patient reported outcomes using mHealth platform in emergency department patients with non-medical opioid use
Hawk K, Malicki C, Kinsman J, D’Onofrio G, Taylor A, Venkatesh A. Feasibility and acceptability of electronic administration of patient reported outcomes using mHealth platform in emergency department patients with non-medical opioid use. Addiction Science & Clinical Practice 2021, 16: 66. PMID: 34758881, PMCID: PMC8579535, DOI: 10.1186/s13722-021-00276-0.Peer-Reviewed Original ResearchConceptsNon-medical opioid useOpioid use disorderOpioid useEmergency departmentED patientsED visitsPrescription medicationsMHealth platformUrban academic emergency departmentEligible adult patientsEmergency department patientsPathways of careTransitions of careAcademic emergency departmentAbsence of patientsElectronic surveyCollection of PROsMeasures of feasibilityOverdose risk behaviorsHalf of participantsMobile health platformNear-term outcomesElectronic health recordsAdult patientsHospital dischargeScenarios to improve CT head utilization in the emergency department delineated by critical results reporting
Tu LH, Venkatesh AK, Malhotra A, Taylor RA, Sheth KN, Forman HP, Yaesoubi R. Scenarios to improve CT head utilization in the emergency department delineated by critical results reporting. Emergency Radiology 2021, 29: 81-88. PMID: 34617133, DOI: 10.1007/s10140-021-01947-w.Peer-Reviewed Original ResearchConceptsAdult ED encountersCommon chief complaintChief complaintEmergency departmentED encountersPatient selectionHead examsLoss of consciousnessAcademic medical centerChest painBlood sugarRetrospective studyHead injuryMental statusNew headacheMedical CenterPsychiatric evaluationConclusionOur studyBetter outcomesAdvanced imagingAlcohol intoxicationTotal encountersComplaintsHeadacheSignificant differencesCOVID-19 Vaccine Acceptance and Access Among Black and Latinx Communities
Balasuriya L, Santilli A, Morone J, Ainooson J, Roy B, Njoku A, Mendiola-Iparraguirre A, Duffany K, Macklin B, Higginbottom J, Fernández-Ayala C, Vicente G, Venkatesh A. COVID-19 Vaccine Acceptance and Access Among Black and Latinx Communities. JAMA Network Open 2021, 4: e2128575. PMID: 34643719, PMCID: PMC8515205, DOI: 10.1001/jamanetworkopen.2021.28575.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccine acceptanceCOVID-19 vaccineCOVID-19 vaccine accessVaccination accessVaccine acceptanceVaccine accessQualified health centersCommunity health workersCOVID-19 vaccinationCOVID-19Health care practitionersHealth care systemPublic health officialsEquitable uptakeHealth centersHealth workersMAIN OUTCOMEFocus groupsInductive content analysis approachCare practitionersHealth departmentsHealth care employeesQualitative studyLocal community-based organizationsDisproportionate deathsHead and Neck CTA Utilization: Analysis of Ordering Frequency and Nonroutine Results Communication, With Focus on the 50 Most Common Emergency Department Clinical Presentations.
Tu LH, Malhotra A, Venkatesh AK, Taylor RA, Sheth KN, Forman HP, Yaesoubi R. Head and Neck CTA Utilization: Analysis of Ordering Frequency and Nonroutine Results Communication, With Focus on the 50 Most Common Emergency Department Clinical Presentations. American Journal Of Roentgenology 2021, 218: 544-551. PMID: 34585611, DOI: 10.2214/ajr.21.26543.Peer-Reviewed Original ResearchConceptsNeck CTAED visitsEmergency departmentNonroutine communicationSingle health care systemAdult ED visitsSubset of reportsRadiologist communicationResult communicationPatient's chief concernHealth care systemFrequency of headCTA utilizationAcute findingsClinical presentationED settingPatient selectionIncidental findingClinical impactCTA examinationsCare systemCTAVisitsHigher numberNegative resultsDisparities in Accessing and Reading Open Notes in the Emergency Department Upon Implementation of the 21st Century CURES Act
Sangal RB, Powers E, Rothenberg C, Ndumele C, Ulrich A, Hsiao A, Venkatesh AK. Disparities in Accessing and Reading Open Notes in the Emergency Department Upon Implementation of the 21st Century CURES Act. Annals Of Emergency Medicine 2021, 78: 593-598. PMID: 34353651, DOI: 10.1016/j.annemergmed.2021.06.014.Peer-Reviewed Original ResearchConceptsProportion of patientsPatient portal accessEmergency departmentOpen notesClinical notesPortal accessPublic insuranceUrgent care centersCentury Cures ActDifferent patient demographicsSingle health systemPatient demographicsPrimary outcomeCures ActPatient utilizationPatient visitsCare centerObservational studyPatientsDigital health toolsAge 18Health systemHealth toolsUnique barriersNon-English speakersEarly Care of Adults With Suspected Sepsis in the Emergency Department and Out-of-Hospital Environment: A Consensus-Based Task Force Report
Yealy DM, Mohr NM, Shapiro NI, Venkatesh A, Jones AE, Self WH. Early Care of Adults With Suspected Sepsis in the Emergency Department and Out-of-Hospital Environment: A Consensus-Based Task Force Report. Annals Of Emergency Medicine 2021, 78: 1-19. PMID: 33840511, DOI: 10.1016/j.annemergmed.2021.02.006.Peer-Reviewed Original Research
2020
Association between patient-physician gender concordance and patient experience scores. Is there gender bias?
Chekijian S, Kinsman J, Taylor RA, Ravi S, Parwani V, Ulrich A, Venkatesh A, Agrawal P. Association between patient-physician gender concordance and patient experience scores. Is there gender bias? The American Journal Of Emergency Medicine 2020, 45: 476-482. PMID: 33069544, DOI: 10.1016/j.ajem.2020.09.090.Peer-Reviewed Original ResearchConceptsPatient satisfaction surveyFemale patientsProvider scoresOverall assessment scoreEmergency departmentPatient satisfactionPhysician genderPatient-physician gender concordanceFemale physiciansAssessment scoresGender concordancePatient satisfaction survey dataSatisfaction surveyEffect of patientFemale emergency physiciansPatient experience scoresLogistic regression modelsCross-sectional analysisElectronic health recordsPatients' oddsAdult patientsPatient genderEmergency physiciansLower oddsEmergency careMedicaid expansion and resource utilization in the emergency department
Janke AT, Danagoulian S, Venkatesh AK, Levy PD. Medicaid expansion and resource utilization in the emergency department. The American Journal Of Emergency Medicine 2020, 38: 2586-2590. PMID: 31982222, DOI: 10.1016/j.ajem.2019.12.050.Peer-Reviewed Original ResearchMeSH KeywordsAdultChest PainComputed Tomography AngiographyCoronary AngiographyDiagnostic Techniques, CardiovascularDisease ManagementEchocardiography, StressEligibility DeterminationEmergency Service, HospitalExercise TestFemaleHealth PolicyHospitalizationHumansMaleMedicaidMedically UninsuredMiddle AgedMyocardial Perfusion ImagingOdds RatioPatient Protection and Affordable Care ActUnited StatesConceptsChest pain visitsOdds of admissionAdvanced cardiac imagingPain visitsAffordable Care ActChest painED visitsMedicaid expansionED visit dataCardiac imagingEmergency department visitsEligibility expansionsSubgroup of patientsExpansion statesLikelihood of admissionProportion of visitsNon-expansion statesMedicaid eligibility expansionsDepartment visitsClinician's discretionEmergency departmentMedicaid patientsAdmissionProvider behaviorVisits
2018
Opening of Psychiatric Observation Unit Eases Boarding Crisis
Parwani V, Tinloy B, Ulrich A, D'Onofrio G, Goldenberg M, Rothenberg C, Patel A, Venkatesh A. Opening of Psychiatric Observation Unit Eases Boarding Crisis. Academic Emergency Medicine 2018, 25: 456-460. PMID: 29266537, DOI: 10.1111/acem.13369.Peer-Reviewed Original ResearchConceptsED LOSLength of stayMedian ED LOSTotal LOSPsychiatric admission ratesCrisis intervention unitSecondary outcomesPrimary outcomeObservation unitAdmission ratesPrimary analysisTertiary care academic medical centerPsychiatric chief complaintsBehavioral health staffInpatient psychiatric bedsAcute psychiatric careAcademic medical centerHours of careEmergency department boardingAdult EDAdult patientsPreintervention periodChief complaintPediatric hospitalInpatient admissions