1999
REGULATION OF NUCLEAR LOCALIZATION: A Key to a Door
Kaffman A, O'Shea E. REGULATION OF NUCLEAR LOCALIZATION: A Key to a Door. Annual Review Of Cell And Developmental Biology 1999, 15: 291-339. PMID: 10611964, DOI: 10.1146/annurev.cellbio.15.1.291.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTranscriptional responseNuclear envelopeDiverse biological processesMovement of proteinsEukaryotic cellsNuclear localizationBiological processesMovement of macromoleculesIntracellular changesCytoplasmRegulationCellsNucleusProteinMacromoleculesEnvelopeLocalizationTransfer of informationResponse
1998
The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus
Kaffman A, Rank N, O'Neill E, Huang L, O'Shea E. The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature 1998, 396: 482-486. PMID: 9853758, DOI: 10.1038/24898.Peer-Reviewed Original ResearchMeSH KeywordsBiological TransportCell NucleusCloning, MolecularCytoplasmDNA-Binding ProteinsEscherichia coliFungal ProteinsGTP PhosphohydrolasesKaryopherinsMutationNuclear ProteinsPhosphorylationProtein BindingRan GTP-Binding ProteinReceptors, Cytoplasmic and NuclearSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsConceptsTranscription factor Pho4Nuclear exportYeast transcription factor Pho4Phosphorylation of Pho4Cyclin-dependent kinasesPho80-Pho85Yeast RanProtein exportPho4Transcription factorsReplication factorsPhosphate availabilityPhosphorylationMsn5ProteinKinaseNuclear complexNucleus2ExportNucleusCyclinGTPCytoplasmBindsMechanismPhosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121
Kaffman A, Rank N, O’Shea E. Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121. Genes & Development 1998, 12: 2673-2683. PMID: 9732266, PMCID: PMC317126, DOI: 10.1101/gad.12.17.2673.Peer-Reviewed Original ResearchMeSH KeywordsBinding SitesCell NucleusCloning, MolecularCytoplasmDNA-Binding ProteinsEscherichia coliFungal ProteinsKineticsMembrane Transport ProteinsPhosphatesPhosphorylationReceptors, Cytoplasmic and NuclearRecombinant ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription Factors
1996
Regulation of PHO4 Nuclear Localization by the PHO80-PHO85 Cyclin-CDK Complex
O'Neill E, Kaffman A, Jolly E, O'Shea E. Regulation of PHO4 Nuclear Localization by the PHO80-PHO85 Cyclin-CDK Complex. Science 1996, 271: 209-212. PMID: 8539622, DOI: 10.1126/science.271.5246.209.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceCell NucleusCulture MediaCyclin-Dependent KinasesCyclinsCytoplasmDipeptidesDNA-Binding ProteinsFungal ProteinsGene Expression Regulation, FungalMembrane Transport ProteinsMolecular Sequence DataMutationPhosphate Transport ProteinsPhosphatesPhosphorylationRepressor ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsConceptsPho80-Pho85 cyclin