TM-15GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO
Venneti S, Dunphy M, Zhang H, Pitter K, Campos C, Carlin S, Lyashchenko S, Plöessl C, Rohle D, Omuro A, Cross J, Brennan C, Weber W, Holland E, Mellinghoff I, Kung H, Lewis J, Thompson C. TM-15GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO. Neuro-Oncology 2014, 16: v216-v216. PMCID: PMC4218624, DOI: 10.1093/neuonc/nou278.14.Peer-Reviewed Original ResearchChemo/radiation therapyClear tumor delineationGlioma animal modelPlasma amino acidsClinical managementIDH1 mutant gliomasAltered glutamine metabolismRadiation therapyAnimal modelsHuman gliomasPten-nullGliomasHigh avidityPET imagingLow uptakeDetection of gliomaTumor delineationHigh uptakeAnaplerotic substrateGlutamine metabolismMetabolic stateVivoBrainGlutamine uptakeMetabolism