2011
Cognitive functions in primary CNS lymphoma after single or combined modality regimens
Correa DD, Shi W, Abrey LE, Deangelis LM, Omuro AM, Deutsch MB, Thaler HT. Cognitive functions in primary CNS lymphoma after single or combined modality regimens. Neuro-Oncology 2011, 14: 101-108. PMID: 22013168, PMCID: PMC3245999, DOI: 10.1093/neuonc/nor186.Peer-Reviewed Original ResearchConceptsWhole brain radiotherapyPrimary CNS lymphomaQuality of lifeHD-MTXWhite matter diseaseModality regimenCNS lymphomaHigh-dose methotrexate-based chemotherapyCognitive impairmentExtensive white matter diseaseMethotrexate-based chemotherapySubset of patientsBaseline neuropsychological evaluationBrain radiotherapyDisease remissionModality regimensMost cognitive domainsStandard treatmentTreatment completionCognitive dysfunctionSufficient severityPatientsNeuropsychological evaluationCognitive functionSubstantial risk
2008
Brain tumors and dementia
Omuro AM, Delattre J. Brain tumors and dementia. Handbook Of Clinical Neurology 2008, 89: 877-886. PMID: 18631803, DOI: 10.1016/s0072-9752(07)01277-8.Peer-Reviewed Original ResearchConceptsCognitive dysfunctionBrain tumorsAdult brain tumor patientsMinor cognitive dysfunctionBrain tumor patientsQuality of lifeDiffuse cognitive dysfunctionSuch patientsTumor patientsPatient's lifeCognitive impairmentPatientsCognitive endpointsCognitive functionDysfunctionCommon typeDementiaTumorsDeleterious impactMildDiagnosisImpairmentTrialsEndpoint