Different Signaling Roles of SHPTP2 in Insulin-induced GLUT1 Expression and GLUT4 Translocation ∗
Hausdorff S, Bennett A, Neel B, Birnbaum M. Different Signaling Roles of SHPTP2 in Insulin-induced GLUT1 Expression and GLUT4 Translocation ∗. Journal Of Biological Chemistry 1995, 270: 12965-12968. PMID: 7768884, DOI: 10.1074/jbc.270.22.12965.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAnimalsBase SequenceBiological TransportDNA PrimersGlucose Transporter Type 1Glucose Transporter Type 4InsulinIntracellular Signaling Peptides and ProteinsMiceMicroinjectionsMolecular Sequence DataMonosaccharide Transport ProteinsMuscle ProteinsProtein Tyrosine Phosphatase, Non-Receptor Type 1Protein Tyrosine Phosphatase, Non-Receptor Type 11Protein Tyrosine Phosphatase, Non-Receptor Type 6Protein Tyrosine PhosphatasesRNA, MessengerSignal TransductionConceptsGLUT4 translocationNon-transmembrane protein tyrosine phosphataseSrc homology 2 domainGlutathione S-transferase fusion proteinS-transferase fusion proteinC-terminal SH2 domainCell surface GLUT1Insulin receptor substrate-1Cell surfaceProtein tyrosine phosphataseInsulin-stimulated mitogenesisTranslocation of GLUT4Insulin-stimulated expressionReceptor substrate-1Insulin-induced DNA synthesisInsulin-stimulated increaseNIH 3T3 fibroblastsSH2 domainSHPTP2Signaling roleSubstrate-1Fusion proteinInsulin stimulationMetabolic pathwaysIndependent pathways