Hepatic inositol 1,4,5 trisphosphate receptor type 1 mediates fatty liver
Feriod CN, Oliveira AG, Guerra MT, Nguyen L, Richards KM, Jurczak MJ, Ruan H, Camporez JP, Yang X, Shulman GI, Bennett AM, Nathanson MH, Ehrlich BE. Hepatic inositol 1,4,5 trisphosphate receptor type 1 mediates fatty liver. Hepatology Communications 2017, 1: 23-35. PMID: 28966992, PMCID: PMC5613674, DOI: 10.1002/hep4.1012.Peer-Reviewed Original ResearchLipid droplet formationFatty liverLiver diseaseHuman fatty liver diseaseFatty liver diseaseNon-alcoholic steatohepatitisDegree of steatosisCalcium signalingHuman liver biopsiesReceptor type 1ER calcium releaseType 1 isoformMitochondrial calcium signalingLiver biopsyHepatic triglyceridesCalcium handlingHepatic expressionKnockout miceTrisphosphate receptor type 1Malignant formUS populationCalcium releaseType 1LiverCommon type