2023
Teaching an old dog new tricks: A new tool for protein tyrosine phosphatase substrate discovery
Bennett A. Teaching an old dog new tricks: A new tool for protein tyrosine phosphatase substrate discovery. Journal Of Biological Chemistry 2023, 299: 104731. PMID: 37080392, PMCID: PMC10193000, DOI: 10.1016/j.jbc.2023.104731.Peer-Reviewed Original ResearchConceptsIdentification of substratesSubstrate discoveryProtein tyrosineProtein substratesInteraction networksBreast cancer cell modelsCancer cell modelsFunctional interactionNovel targetVersatile new toolNew toolCell modelComplete understandingRecent studiesOld dog new tricksNew tricksInteractorsPTP1B.PTP1BPTPMutationsSubstrateEnzymeTyrosinePathway
2013
Mitogen-Activated Protein Kinase Phosphatases in Metabolism
Lawan A, Bennett A. Mitogen-Activated Protein Kinase Phosphatases in Metabolism. 2013, 221-238. DOI: 10.1007/978-1-4614-7855-3_12.Peer-Reviewed Original ResearchMitogen-activated protein kinaseMetabolic homeostasisProtein kinaseTissue-specific mannerFamily of enzymesDirect dephosphorylationPathophysiological signalingMAPK activityMAPK inactivationMetabolic signalingImportant playersMKPHomeostasisKinaseCritical roleSignalingBody of evidenceMetabolismDephosphorylationComplex networksComparable levelsEnzymeMitogenPathwayRegulation