Phenobarbital-inducible Aldehyde Dehydrogenase in the Rat cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats
Dunn TJ, Koleske AJ, Lindahl R, Pitot HC. Phenobarbital-inducible Aldehyde Dehydrogenase in the Rat cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats. Journal Of Biological Chemistry 1989, 264: 13057-13065. PMID: 2753900, DOI: 10.1016/s0021-9258(18)51595-7.Peer-Reviewed Original ResearchConceptsComplete nucleotide sequenceSpecific gene expressionAldehyde dehydrogenaseAmino acid sequenceGlutathione S-transferase YaRat cDNA sequenceStrong conservationCDNA sequenceNucleotide sequenceMRNA speciesAcid sequenceGene expressionCytosolic isozymeMolecular massAmino acidsCytochrome P-450eMultiple pathwaysMRNAResponsive allelesMRNA levelsSequenceRegulationCytochrome P-450bDehydrogenaseP-450e