2020
Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold
Kaur N, Han W, Li Z, Madrigal MP, Shim S, Pochareddy S, Gulden FO, Li M, Xu X, Xing X, Takeo Y, Li Z, Lu K, Imamura Kawasawa Y, Ballester-Lurbe B, Moreno-Bravo JA, Chédotal A, Terrado J, Pérez-Roger I, Koleske AJ, Sestan N. Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. Neuron 2020, 107: 1197-1211.e9. PMID: 32707082, PMCID: PMC7529949, DOI: 10.1016/j.neuron.2020.06.035.Peer-Reviewed Original ResearchConceptsNeural stem cellsDendritic spine formationNeural circuit formationRadial glia-like neural stem cellsMedial ganglionic eminenceRadial fibersAxon guidanceStem cellsCorticospinal neuronsGlobus pallidusMacroglial cellsGanglionic eminenceCircuit formationVentricular zoneSpine formationRnd3/RhoENeuronsMidline crossingExpression of Rnd3Rho GTPaseCellsExpressionUnexpected roleAtypical Rho GTPaseRnd3
1995
The RNA polymerase II holoenzyme and its implications for gene regulation
Koleske A, Young R. The RNA polymerase II holoenzyme and its implications for gene regulation. Trends In Biochemical Sciences 1995, 20: 113-116. PMID: 7709429, DOI: 10.1016/s0968-0004(00)88977-x.Peer-Reviewed Original ResearchConceptsRNA polymerase II holoenzymeTranscription initiation apparatusGeneral transcription factorsRNA polymerase holoenzymeGene regulationPol IIPolymerase holoenzymeTranscriptional regulatorsTranscription factorsB proteinGene expressionLarge complexesSRB componentsHoloenzymeRegulationRecent evidenceComplexesSuppressorRegulatorProteinExpression