A scalable and cost-efficient rRNA depletion approach to enrich RNAs for molecular biology investigations
Singh A, Xue A, Tai J, Mbadugha F, Obi P, Mascarenhas R, Tyagi A, Siena A, Chen Y. A scalable and cost-efficient rRNA depletion approach to enrich RNAs for molecular biology investigations. RNA 2024, 30: rna.079761.123. PMID: 38485192, PMCID: PMC11098455, DOI: 10.1261/rna.079761.123.Peer-Reviewed Original ResearchConceptsDepleting rRNACellular processesAbundance of rRNAMolecular biological investigationsNon-rRNA transcriptsComplex regulatory networkInvestigate gene expressionRRNA removalRRNA moleculesHistone mRNARegulatory networksSmall RNAsPositive selectionRRNARNA inputBiological investigationsTranscriptome analysisLong noncoding RNAsGene expressionRegulatory mechanismsRNAOff-target effectsNoncoding RNAsCircular RNAsTranscription