Featured Publications
Deep Vein Thrombosis: Update on Mechanical Thrombectomy and Intravascular US.
Sailer A, Revzin MV, Pollak J, Ayyagari R, Mojibian HR, Nezami N, Pellerito JS, Marino AG. Deep Vein Thrombosis: Update on Mechanical Thrombectomy and Intravascular US. RadioGraphics 2022, 42: e184-e185. PMID: 36190870, DOI: 10.1148/rg.220031.Peer-Reviewed Original ResearchSequelae of Eating Disorders at Imaging
Solomon N, Sailer A, Dixe de Oliveira Santo I, Pillai A, Heng LXX, Jha P, Katz DS, Zulfiqar M, Sugi M, Revzin MV. Sequelae of Eating Disorders at Imaging. RadioGraphics 2022, 42: 1377-1397. PMID: 35930473, DOI: 10.1148/rg.220018.Peer-Reviewed Educational MaterialsConceptsMedical historyPatient's medical historyHigh mortality rateOverview of managementClinical presentationMedical complicationsRelated complicationsImaging findingsPhysical examinationUncommon sequelaMedical attentionOnline supplemental materialPsychiatric disordersMedical treatmentMortality rateOrgan systemsSequelaeDisordersDiagnosisComplicationsPatientsPathophysiologySocial stigmaLaboratory resultsRadiologistsIncidental Ovarian and Uterine Findings on Cross-sectional Imaging
Revzin MV, Sailer A, Moshiri M. Incidental Ovarian and Uterine Findings on Cross-sectional Imaging. Radiologic Clinics Of North America 2021, 59: 661-692. PMID: 34053612, DOI: 10.1016/j.rcl.2021.03.013.Peer-Reviewed Original ResearchConceptsUterine findingsCross-sectional imaging examinationsIncidental adnexal massesBenign ovarian cystsCross-sectional imagingPostmenopausal womenOvarian cystsSurgical interventionGynecologic disordersAdnexal massesUnnecessary imagingIncidental findingImaging examinationsDisordersImagingManagement recommendationsFindingsIncidentalomasHigh frequencyCystsDiagnosis
2023
Intestinal Epithelial Digestive, Transport, and Barrier Protein Expression Is Increased in Environmental Enteric Dysfunction
Abtahi S, Sailer A, Roland J, Haest X, Chanez-Paredes S, Ahmad K, Sadiq K, Iqbal N, Ali S, Turner J. Intestinal Epithelial Digestive, Transport, and Barrier Protein Expression Is Increased in Environmental Enteric Dysfunction. Laboratory Investigation 2023, 103: 100036. PMID: 36870290, PMCID: PMC10121737, DOI: 10.1016/j.labinv.2022.100036.Peer-Reviewed Original Research
2019
Differential regulation of claudin-2 and claudin-15 expression in children and adults with malabsorptive disease
Ong MLDM, Yeruva S, Sailer A, Nilsen SP, Turner JR. Differential regulation of claudin-2 and claudin-15 expression in children and adults with malabsorptive disease. Laboratory Investigation 2019, 100: 483-490. PMID: 31605016, PMCID: PMC7047618, DOI: 10.1038/s41374-019-0324-8.Peer-Reviewed Original ResearchConceptsCommon variable immunodeficiencyInflammatory bowel diseaseClaudin-15 expressionCeliac diseaseMalabsorptive diseaseClaudin-2 expressionClaudin-2Claudin-15Host diseaseDuodenal biopsiesBowel diseaseVariable immunodeficiencyHealthy childrenHealthy controlsNutrient cotransportPostnatal developmentGVHDDiseaseSpecific claudinsQuantitative immunofluorescence microscopyAdultsChildrenImmunofluorescence microscopyDifferential regulationExpression changes
2018
Environmental Enteropathy in Undernourished Pakistani Children: Clinical and Histomorphometric Analyses
Syed S, Yeruva S, Herrmann J, Sailer A, Sadiq K, Iqbal N, Kabir F, Ahmed K, Qureshi S, Moore SR, Turner J, Ali SA. Environmental Enteropathy in Undernourished Pakistani Children: Clinical and Histomorphometric Analyses. American Journal Of Tropical Medicine And Hygiene 2018, 98: 1577-1584. PMID: 29611507, PMCID: PMC6086170, DOI: 10.4269/ajtmh.17-0306.Peer-Reviewed Original ResearchConceptsCeliac diseaseUnderwent upper endoscopyB cell aggregatesHost disease patientsUse therapeutic foodAge-matched specimensResource-poor countriesT lymphocytosisIntraepithelial lymphocytosisDuodenal biopsiesUpper endoscopyVillous atrophyLymphocytic activationEnvironmental enteropathyImmunological featuresDisease patientsMalnourished infantsHealthy controlsNutritional supplementationNutrition interventionsT lymphocytesLamina propriaInsufficient responseTherapeutic foodBirth cohort
2017
Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia
Amadi B, Besa E, Zyambo K, Kaonga P, Louis-Auguste J, Chandwe K, Tarr PI, Denno DM, Nataro JP, Faubion W, Sailer A, Yeruva S, Brantner T, Murray J, Prendergast AJ, Turner JR, Kelly P. Impaired Barrier Function and Autoantibody Generation in Malnutrition Enteropathy in Zambia. EBioMedicine 2017, 22: 191-199. PMID: 28750860, PMCID: PMC5552244, DOI: 10.1016/j.ebiom.2017.07.017.Peer-Reviewed Original ResearchConceptsSevere acute malnutritionHealthy childrenVillus heightIntestinal barrier failureImpaired barrier functionBacterial translocationImmune dysregulationIntestinal damageIntestinal secretionPersistent diarrheaAcute malnutritionAutoantibody generationHistological lesionsMalnourished childrenTranslocation markersCrypt depthNormal rangeHealthy adultsIgG concentrationsClaudin-4Adult controlsAnalysis of markersBarrier functionMalnutritionEpithelial surface