2023
Management of Anal Incontinence With Implantable Sacral Neuromodulation
Esposito A, Mongiu A. Management of Anal Incontinence With Implantable Sacral Neuromodulation. Diseases Of The Colon & Rectum 2023, 66: 758-762. PMID: 36989061, DOI: 10.1097/dcr.0000000000002890.Peer-Reviewed Original ResearchWhat Every Colorectal Surgeon Needs to Know About Colorectal Surgery Practice and the American Medical Association
Mongiu A, Tyler K, Surgeons O. What Every Colorectal Surgeon Needs to Know About Colorectal Surgery Practice and the American Medical Association. Diseases Of The Colon & Rectum 2023, 66: 755-757. PMID: 36799762, DOI: 10.1097/dcr.0000000000002777.Peer-Reviewed Original ResearchSo You Want to be a Program Director? Career Paths of Colon and Rectal Surgery Residency Program Directors
Esposito A, Coppersmith N, Flom E, Chung M, Reddy V, Leeds I, Longo W, Pantel H, Yoo P, Mongiu A. So You Want to be a Program Director? Career Paths of Colon and Rectal Surgery Residency Program Directors. Journal Of Surgical Education 2023, 80: 588-596. PMID: 36658062, DOI: 10.1016/j.jsurg.2022.12.009.Peer-Reviewed Original Research
2022
How Far Is Too Far? Cost-Effectiveness Analysis of Regionalized Rectal Cancer Surgery
Leeds I, Xu Z, Loria A, Pantel H, Mongiu A, Longo W, Reddy V. How Far Is Too Far? Cost-Effectiveness Analysis of Regionalized Rectal Cancer Surgery. Diseases Of The Colon & Rectum 2022, 66: 467-476. PMID: 36538713, DOI: 10.1097/dcr.0000000000002636.Peer-Reviewed Original ResearchConceptsMultivariable probabilistic sensitivity analysesCost-effectiveness standardsIncremental cost-effectiveness ratioProbabilistic sensitivity analysesCost-effectiveness analysisCost-effectiveness ratioTotal societal costsSensitivity analysisDecision analysis modelEl análisisSocietal perspectiveIncremental costPacientes con cáncerSocietal costsLos costosLargo plazoPolicy levelDecision analysisTotal costCostDo Cultures From Percutaneously Drained Intra-abdominal Abscesses Change Treatment? A Retrospective Review
Esposito A, Zhang Y, Nagarkatti N, Laird W, Coppersmith N, Reddy V, Leeds I, Mongiu A, Longo W, Hao R, Pantel H. Do Cultures From Percutaneously Drained Intra-abdominal Abscesses Change Treatment? A Retrospective Review. Diseases Of The Colon & Rectum 2022, 66: 451-457. PMID: 36538708, DOI: 10.1097/dcr.0000000000002644.Peer-Reviewed Original ResearchConceptsIntra-abdominal abscessPercutaneous drainAntimicrobial therapyLos pacientesAbdominal abscessSingle university-affiliated institutionRetrospective medical record reviewEmpiric antibiotic regimensSolid organ transplantsMedical record reviewUniversity-affiliated institutionCulture dataAntibiotic coursesAbdominal infectionAntibiotic regimensActive smokersMedian ageActive chemotherapyRecord reviewEvidence-based practiceMedian lengthUtility of cultureFemale sexIntraoperative culturesInclusion criteriaNatural Orifice Placement of EEA: the NOPE technique
Pantel H, Longo W, Leeds I, Mongiu A, Reddy V. Natural Orifice Placement of EEA: the NOPE technique. Techniques In Coloproctology 2022, 26: 921-921. PMID: 35729461, DOI: 10.1007/s10151-022-02638-5.Peer-Reviewed Original ResearchDo You Get What You Pay For? The Relationship of Price and Quality in Hospital Provided Procedures
Esposito AC, Laird WD, Zhang Y, Cerullo M, Li AX, Coppersmith NA, Reddy V, Leeds I, Mongiu A, Longo W, Pantel H. Do You Get What You Pay For? The Relationship of Price and Quality in Hospital Provided Procedures. Journal Of Surgical Research 2022, 278: 140-148. PMID: 35598497, DOI: 10.1016/j.jss.2022.04.035.Peer-Reviewed Original Research
2017
Complex sclerosing lesions and radial sclerosing lesions on core needle biopsy: Low risk of carcinoma on excision in cases with clinical and imaging concordance
Nakhlis F, Lester S, Denison C, Wong SM, Mongiu A, Golshan M. Complex sclerosing lesions and radial sclerosing lesions on core needle biopsy: Low risk of carcinoma on excision in cases with clinical and imaging concordance. The Breast Journal 2017, 24: 133-138. PMID: 28685897, DOI: 10.1111/tbj.12859.Peer-Reviewed Original ResearchConceptsCore needle biopsyRadial sclerosing lesionsCore biopsyNeedle biopsyIpsilateral cancerObservation groupSclerosing lesionsUpgrade rateFuture breast cancer riskOverall upgrade rateRate of malignancyBreast cancer riskImage-guided breast biopsyExcision groupMedian ageClinical variablesMalignancy rateUncommon diagnosisNonpalpable lesionsCancer riskExcised specimensLower riskBiopsyLow lesionsBreast biopsyAn Unusual Cause of Intestinal Perforation
Pernar LI, Mongiu A, Sheu EG. An Unusual Cause of Intestinal Perforation. JAMA Surgery 2017, 152: 199-200. PMID: 27926750, DOI: 10.1001/jamasurg.2016.4614.Peer-Reviewed Original Research
2010
Reconstruction of late‐onset transplant ureteral stricture disease
Helfand BT, Newman JP, Mongiu AK, Modi P, Meeks JJ, Gonzalez CM. Reconstruction of late‐onset transplant ureteral stricture disease. BJU International 2010, 107: 982-987. PMID: 20825404, DOI: 10.1111/j.1464-410x.2010.09559.x.Peer-Reviewed Original ResearchConceptsTransplant ureteral stricturesUreteral strictureGraft failureImmunosuppressive drug regimenKidney-pancreas transplantationStable allograft functionBaseline clinical characteristicsSerum creatinine levelsUrinary tract infectionLarge patient cohortUreteral stricture diseaseTime of reconstructionAllograft functionPostoperative complicationsRenal transplantationClinical characteristicsCreatinine levelsDrug regimenTract infectionsBalloon dilationMedian ageRepeat dilationStricture recurrenceSurgical managementOpen reconstruction
2009
Lower urinary tract symptoms, benign prostatic hyperplasia, and obesity
Mongiu AK, McVary KT. Lower urinary tract symptoms, benign prostatic hyperplasia, and obesity. Current Urology Reports 2009, 10: 247-253. PMID: 19570484, DOI: 10.1007/s11934-009-0041-8.Peer-Reviewed Original ResearchConceptsLower urinary tract symptomsBenign prostatic hyperplasiaBPH/lower urinary tract symptomsUrinary tract symptomsLifestyle modificationTract symptomsProstatic hyperplasiaGlobal public health challengeParticular polymorphismsCommon neoplastic conditionPrevalence of obesityClinical trial methodologyPublic health challengeStrong independent relationshipProstate sizePhysical inactivityTrial methodologyNeoplastic conditionsEpidemiological studiesObesityHealth challengesIndependent relationshipIndividual treatmentHyperplasiaSymptomsVariation in Institutional Review Board Responses to a Standard Protocol for a Multicenter Randomized, Controlled Surgical Trial
Helfand BT, Mongiu AK, Roehrborn CG, Donnell RF, Bruskewitz R, Kaplan SA, Kusek JW, Coombs L, McVary KT, Investigators M. Variation in Institutional Review Board Responses to a Standard Protocol for a Multicenter Randomized, Controlled Surgical Trial. Journal Of Urology 2009, 181: 2674-2679. PMID: 19375101, PMCID: PMC4720253, DOI: 10.1016/j.juro.2009.02.032.Peer-Reviewed Original ResearchConceptsInstitutional review boardStudy protocolSurgical trialsReview boardMulticenter trialLocal institutional review board reviewIdentical study protocolMulticenter surgical trialInstitutional review board approvalInvasive surgical therapiesBenign prostatic hyperplasiaMulticenter clinical trialReview board approvalSurgical therapyMedical therapyMulticenter RandomizedSurgical interventionProstatic hyperplasiaClinical trialsBoard approvalInstitutional review board reviewTrialsType of responseSecond reviewTherapyOutcomes of radical prostatectomy for patients with clinical stage T1a and T1b disease
Helfand BT, Mongiu AK, Kan D, Kim D, Loeb S, Roehl KA, Meeks JJ, Smith ND, Catalona WJ. Outcomes of radical prostatectomy for patients with clinical stage T1a and T1b disease. BJU International 2009, 104: 304-309. PMID: 19239451, DOI: 10.1111/j.1464-410x.2009.08421.x.Peer-Reviewed Original ResearchConceptsRadical retropubic prostatectomyClinical stage T1c diseaseStage T1c diseaseT1b diseaseT1c diseaseGleason scoreB diseasePathological featuresProstate cancerLower preoperative prostate-specific antigen levelsFavorable long-term functional outcomesPreoperative prostate-specific antigen levelLower cancer-specific survivalProstate-specific antigen levelLong-term functional outcomeClinical stage T1aStage T1b diseaseT1a/bT1b prostate cancerAdverse pathological featuresCancer-specific survivalOrgan-confined diseaseYear of surgeryOverall survival rateAggressive pathological featuresSmall bowel perforation during suprapubic tube exchange.
Mongiu AK, Helfand BT, Kielb SJ. Small bowel perforation during suprapubic tube exchange. Canadian Journal Of Urology 2009, 16: 4519-21. PMID: 19222896.Peer-Reviewed Original ResearchConceptsSuprapubic tube placementTube placementTube exchangeRecurrent urinary tract infectionsSmall bowel perforationUrinary tract infectionCommon urological proceduresBowel perforationCatheter blockageRare complicationTract infectionsSerious complicationsAdjacent organsLower incidenceUrological proceduresComplicationsInjuryPerforationPlacementInitial placementHematuriaPatientsIleumInfectionIncidence
2008
Ureterovaginal Fistula Formation After Oocyte Retrieval
Mongiu AK, Helfand BT, Kielb SJ. Ureterovaginal Fistula Formation After Oocyte Retrieval. Urology 2008, 73: 444.e1-444.e3. PMID: 18384861, DOI: 10.1016/j.urology.2008.02.042.Peer-Reviewed Original ResearchConceptsOocyte retrievalTransvaginal ultrasound-guided oocyte retrievalUltrasound-guided oocyte retrievalPercutaneous nephrostomy tubeType of injuryOverall complicationsRare complicationPrompt diagnosisUreterovaginal fistulaVaginal hemorrhageFistula formationNephrostomy tubeUltrasound guidanceComplicationsFistulaInjuryHemorrhageUreterInfectionPhysiciansDiagnosis
2002
Intermediate filament–membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength
Huen A, Park J, Godsel L, Chen X, Bannon L, Amargo E, Hudson T, Mongiu A, Leigh I, Kelsell D, Gumbiner B, Green K. Intermediate filament–membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength. Journal Of Cell Biology 2002, 159: 1005-1017. PMID: 12499357, PMCID: PMC2173978, DOI: 10.1083/jcb.200206098.Peer-Reviewed Original ResearchMeSH KeywordsActin CytoskeletonActinsBiotinylationCadherinsCell AdhesionCell LineCell MembraneCytoskeletal ProteinsCytoskeletonDesmogleinsDesmoplakinsDesmosomesDetergentsDNA, ComplementaryGreen Fluorescent ProteinsHumansIntermediate FilamentsKeratinocytesKeratoderma, PalmoplantarL-Lactate DehydrogenaseLuminescent ProteinsMicroscopy, FluorescenceProtein BindingProtein Structure, TertiaryTime FactorsTransfectionTumor Cells, CulturedConceptsMembrane attachmentAdherens junctionsIntermediate filamentsIntercellular adhesive strengthCell surface distributionDetergent-insoluble poolIF cytoskeletonPlasma membraneIntercellular adhesionLatrunculin AActin filamentsJunctional plaquesA431 cellsTerminal truncationDesmosomal proteinsCell aggregatesTissue integrityWeakly adherentLactate dehydrogenase releaseReduced adhesionFacilitate formationCell sheetsNormal keratinocytesSpecific decreaseDehydrogenase release