An Adenosine Receptor-Krüppel-like Factor 4 Protein Axis Inhibits Adipogenesis*
Eisenstein A, Carroll S, Johnston-Cox H, Farb M, Gokce N, Ravid K. An Adenosine Receptor-Krüppel-like Factor 4 Protein Axis Inhibits Adipogenesis*. Journal Of Biological Chemistry 2014, 289: 21071-21081. PMID: 24928509, PMCID: PMC4110311, DOI: 10.1074/jbc.m114.566406.Peer-Reviewed Original ResearchConceptsKruppel-like factor 4Regulator of stem cell maintenanceRegulator of adipocyte differentiationStem cell maintenanceInhibit differentiationRegulator of adipogenesisAdenosine receptorsKnockdown of KLF4Adipose tissue of obese subjectsAdipose tissue developmentExtracellular ligandsA2B adenosine receptorsKruppel-like factor 4 expressionCell maintenanceExpression of Kruppel-like factor 4Signaling cascadesSignaling moleculesAdipocyte differentiationAdipose biologyStromal vascular cellsTissue developmentAdipocyte progenitorsInhibit adipogenesisObese subjectsA2bAR activation