Adrenergic nerves activate an angio-metabolic switch in prostate cancer
Zahalka AH, Arnal-Estapé A, Maryanovich M, Nakahara F, Cruz CD, Finley LWS, Frenette PS. Adrenergic nerves activate an angio-metabolic switch in prostate cancer. Science 2017, 358: 321-326. PMID: 29051371, PMCID: PMC5783182, DOI: 10.1126/science.aah5072.Peer-Reviewed Original ResearchMeSH KeywordsAlkyl and Aryl TransferasesAnimalsCarrier ProteinsElectron Transport Complex IVEndothelium, VascularGene DeletionHumansMaleMembrane ProteinsMiceMitochondrial ProteinsNeovascularization, PathologicNerve FibersNorepinephrineOxidative PhosphorylationProstateProstatic NeoplasmsReceptors, Adrenergic, beta-2Signal TransductionTumor Microenvironment