2019
Germinal center B cell initiation, GC maturation, and the coevolution of its stromal cell niches
Haberman AM, Gonzalez DG, Wong P, Zhang T, Kerfoot SM. Germinal center B cell initiation, GC maturation, and the coevolution of its stromal cell niches. Immunological Reviews 2019, 288: 10-27. PMID: 30874342, PMCID: PMC10234181, DOI: 10.1111/imr.12731.Peer-Reviewed Original Research
2000
A B-cell receptor-specific selection step governs immature to mature B cell differentiation
Levine M, Haberman A, Sant'Angelo D, Hannum L, Cancro M, Janeway C, Shlomchik M. A B-cell receptor-specific selection step governs immature to mature B cell differentiation. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 2743-2748. PMID: 10688906, PMCID: PMC16000, DOI: 10.1073/pnas.050552997.Peer-Reviewed Original ResearchConceptsImmature B cellsMature B cellsB cell receptor repertoirePositive selection eventsB cell differentiationReceptor repertoireSelection eventsCell differentiationB cellsChain pairsCell receptor repertoirePeripheral B cellsReceptor specificityTime cellsMajor forceCell fractionCellsAdaptive immune responsesRepertoireConventional B cellsAvailable repertoireSelection stepImmune responseB cell fractionsSignificant skewing